Abstract: Systems and methods for dynamic collection of probes may employ a probe collector process that runs in conjunction with (or following) a memory garbage collection operation. In response to receiving data indicating that a probe is to be removed from an application and encountering the probe during execution of the application, the probe may be marked for removal. The probe collector process may subsequently remove the probe by replacing some or all of the probe code with NOP instructions. If the probe code for a probe marked for removal includes a call to a probe stub, the probe collector process may replace the call with a NOP instruction. In response to receiving data indicating that the removed probe should be reactivated, the NOP instruction(s) may be replaced with the previously removed probe code. Probe code for probes that are not marked for removal or that are reactivated may be executed.