Abstract: The present invention describes the action of a new family of drugs against a number of Leishmania species and Trypanosona cruzi, for the treatment of cutaneous, mucocutaneous and visceral leishmaniosis as well as tripanosomosis. In vitro assays and studies conducted in animal models and in human patients demonstrated that the compounds had a higher activity compared to drugs in clinical use against Leishmania mexicana amazonensis, L. donovani infantum, L. braziliensis braziliensis and Trypanosoma cruzi. The pharmaceutical activity of compositions based on such family of compounds was evidenced and supports its human and veterinary application for the treatment of the above-mentioned diseases by using different administration routes.

Abstract: A microcidal composition consisting of a water-soluble polymer and the active principle 1-(5-bromophur-2-yl)-2-bromo-2-nitroethene is provided to be used as chemical sterilizer of culture media for the control of bacterial and fungal contaminants. This technical solution, even can be used for the sterilization of solid and liquid culture media, is particularly useful in the production of “in vitro” cultivated plants, and surprisingly was found that its utilization can substitute completely the previous process of sterilization that this media require and even more, the addition of the necessary hormones in the rootage process of “in vitro” plants of crops.