Patents by Inventor Ning Ke
Ning Ke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240086690Abstract: The present disclosure relates to a spike event decision-making device, method, chip, and electronic device to eliminate inherent delays of an output spike event of the neuromorphic chip when reading decisions. The spike event decision-making device includes a first counting module configured to count a number of input spike events of the spiking neural network, a second counting module configured to count some or all of the output spike events of the spiking neural network; and a decision-making module configured to generate a decision-making result according to numbers of spike events fired by neurons in an output layer of the spiking neural network when the number counted by the first counting module reaches a first predetermined value, or when the total count counted by the second counting module reaches a second predetermined value.Type: ApplicationFiled: January 14, 2022Publication date: March 14, 2024Applicants: Chengdu SynSense Technology Co., Ltd., ShenZhen SynSense Technology Co., Ltd.Inventors: Peng ZHOU, Yannan XING, Ning QIAO, Yudi REN, Zheng KE, Yalun HU, Bo LI, Yuhang LIU, Xiwen GONG, Sadique UI Ameen SHEIK, Dylan RICHARD MUIR, Tugba DEMIRCI
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Patent number: 11722550Abstract: An input device is shared between a first remote desktop having a first display image, which is displayed on a first display of a first client device, and a second remote desktop having a second display image, which is displayed on a second display of a second client device. Upon detecting that an input pointer of the input device currently displayed within the first display image on the first display, is moved across an edge of the first remote desktop that corresponds to a virtual boundary between the first remote desktop and the second remote desktop, instructions are issued to a first remote computing device that is hosting the first remote desktop to discontinue receiving inputs made with the input device and a second remote computing device that is hosting the second remote desktop to begin receiving inputs made with the input device.Type: GrantFiled: August 8, 2019Date of Patent: August 8, 2023Assignee: VMware, Inc.Inventors: Lin Lv, Yunfei San, Yunxia Cheng, Jack Liu, Ning Ke, Yang Liu, Jian Ken Song
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Publication number: 20210006615Abstract: An input device is shared between a first remote desktop having a first display image, which is displayed on a first display of a first client device, and a second remote desktop having a second display image, which is displayed on a second display of a second client device. Upon detecting that an input pointer of the input device currently displayed within the first display image on the first display, is moved across an edge of the first remote desktop that corresponds to a virtual boundary between the first remote desktop and the second remote desktop, instructions are issued to a first remote computing device that is hosting the first remote desktop to discontinue receiving inputs made with the input device and a second remote computing device that is hosting the second remote desktop to begin receiving inputs made with the input device.Type: ApplicationFiled: August 8, 2019Publication date: January 7, 2021Inventors: Lin LV, Yunfei SAN, Yunxia CHENG, Jack LIU, Ning KE, Yang LIU, Jian Ken SONG
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Patent number: 10620188Abstract: Methods of identifying whether a biologically active agent affects an oncogene addicted pathway within a cancer cell, by introducing a biologically active agent suspected of affecting an oncogene addicted pathway to a first well and a negative control to a second well, and introducing a stimulating agent that stimulates the oncogene addicted pathway to both wells; monitoring cell-substrate impedance of the two wells and optionally determining cell indices from impedance values; generating an impedance based curve for each of the two wells from the impedance values or from the cell indices; comparing the impedance-based curves to determine a degree of similarity; and if significantly different concluding the biologically active agent affects the oncogene addicted pathway within the cancer cells.Type: GrantFiled: June 2, 2017Date of Patent: April 14, 2020Assignee: ACEA Biosciences, Inc.Inventors: Yama A. Abassi, Li Zhao, Ning Ke, Xiaobo Wang, Xiao Xu
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Patent number: 10215748Abstract: Use of impedance devices in methods of generating a time dependent cellular profiles (TCRP) for the modulation of oncogene addicted cells and comparing the impedance-based TCRP to controls or knowns to identify signature time dependent cellular profiles.Type: GrantFiled: February 23, 2012Date of Patent: February 26, 2019Assignee: ACEA Biosciences, Inc.Inventors: Yama A. Abassi, Li Zhao, Ning Ke, Xiaobo Wang, Xiao Xu
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Publication number: 20170269062Abstract: Methods of identifying whether a biologically active agent affects an oncogene addicted pathway within a cancer cell, by introducing a biologically active agent suspected of affecting an oncogene addicted pathway to a first well and a negative control to a second well, and introducing a stimulating agent that stimulates the oncogene addicted pathway to both wells; monitoring cell-substrate impedance of the two wells and optionally determining cell indices from impedance values; generating an impedance based curve for each of the two wells from the impedance values or from the cell indices; comparing the impedance-based curves to determine a degree of similarity; and if significantly different concluding the biologically active agent affects the oncogene addicted pathway within the cancer cells.Type: ApplicationFiled: June 2, 2017Publication date: September 21, 2017Inventors: Yama A. Abassi, Li Zhao, Ning Ke, Xiaobo Wang, Xiao Xu
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Patent number: 9200246Abstract: An insert device and co-culture device assembly incorporating the insert device, which includes an insert chamber with two fluid impermeable side walls that extend from a microporous bottom to an open top to form an inner cavity. The first side wall is shaped to form a convex arc that follows between about half of a circumference of the well and less than an entire circumference of the well. The second side wall joins ends of the first side wall and protrudes inward towards a center of the convex arc. A flange extends outward from or beneath the top and is notched to form a gap adjacent to the second side wall, which forms an access port allowing access to the lower chamber with a micropipette tip when the insert device is inserted into a well of a single or multi-well plate.Type: GrantFiled: December 1, 2011Date of Patent: December 1, 2015Assignee: ACEA Biosciences, Inc.Inventors: Donald Thomas, Wei Li, Ning Ke, Nan Li, Adrian Papas, Manfred Watzele, Alexander Seiler, Tianxing Wang, Yama Abassi, Xiaobo Wang
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Publication number: 20130143254Abstract: An insert device and co-culture device assembly incorporating the insert device, which includes an insert chamber with two fluid impermeable side walls that extend from a microporous bottom to an open top to form an inner cavity. The first side wall is shaped to form a convex arc that follows between about half of a circumference of the well and less than an entire circumference of the well. The second side wall joins ends of the first side wall and protrudes inward towards a center of the convex arc. A flange extends outward from or beneath the top and is notched to form a gap adjacent to the second side wall, which forms an access port allowing access to the lower chamber with a micropipette tip when the insert device is inserted into a well of a single or multi-well plate.Type: ApplicationFiled: December 1, 2011Publication date: June 6, 2013Applicants: ROCHE DIAGNOSTICS OPERATIONS, INC., ACEA BIOSCIENCES, INC.Inventors: Donald Thomas, Wei Li, Ning Ke, Nan Li, Adrian Papas, Manfred Watzele, Alexander Seiler, Tianxing Wang, Yama Abassi, Xiaobo Wang
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Publication number: 20120322050Abstract: Use of impedance devices in methods of generating a time dependent cellular profiles (TCRP) for the modulation of oncogene addicted cells and comparing the impedance-based TCRP to controls or knowns to identify signature time dependent cellular profiles.Type: ApplicationFiled: February 23, 2012Publication date: December 20, 2012Inventors: Yama A. Abassi, Li Zhao, Ning Ke, Xiabo Wang, Xiao Xu
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Patent number: 8119410Abstract: A novel human member of the Bcl-2 family Bcl-B has been identified, which is closest in amino-acid sequence homology to the Boo (Diva) protein. The Bcl-B protein is widely expressed in adult human tissues. The Bcl-B protein modulates apoptosis. Bcl-B also binds Bcl-2, BCl-XL, and Bax but not Bak. Bcl-B displays a unique pattern of selectivity for binding and regulating the function of other members of the Bcl-2 family.Type: GrantFiled: November 15, 2010Date of Patent: February 21, 2012Assignee: Sanford-Burnham Medical Research InstituteInventors: John C. Reed, Ning Ke, Adam Godzik
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Publication number: 20110190168Abstract: A novel human member of the Bcl-2 family Bcl-B has been identified, which is Closest in amino-acid sequence homology to the Boo (Diva) protein. The Bcl-B protein is Widely expressed in adult human tissues. The Bcl-B protein modulates apoptosis. Bcl-B also binds Bcl-2, BCl-XL, and Bax but not Bak. Bcl-B displays a unique pattern of selectivity for binding and regulating the function of other members of the Bcl-2 family.Type: ApplicationFiled: November 15, 2010Publication date: August 4, 2011Applicant: Sanford-Burnham Medical Research InstituteInventors: John C. Reed, Ning Ke, Adam Godzik
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Patent number: 7846681Abstract: A novel human member of the Bcl-2 family Bcl-B has been identified, which is closest in amino-acid sequence homology to the Boo (Diva) protein. The Bcl-B protein is widely expressed in adult human tissues. The Bcl-B protein modulates apoptosis. Bcl-B also binds Bcl-2. BCl-XL, and Bax but not Bak. Bcl-B displays a unique pattern of selectivity for binding and regulating the function of other members of the Bcl-2 family. Accordingly, provided herein is a method for identifying a molecule that binds to the Bcl-B polypeptide, by contacting the Bcl-B polypeptide with a test molecule and determining whether the test molecule binds to the polypeptide.Type: GrantFiled: April 20, 2009Date of Patent: December 7, 2010Assignee: Sanford-Burnham Medical Research InstituteInventors: John C. Reed, Ning Ke, Adam Godzik
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Publication number: 20090305904Abstract: A novel human member of the Bcl-2 family Bcl-B has been identified, which is closest in amino-acid sequence homology to the Boo (Diva) protein. The Bcl-B protein is widely expressed in adult human tissues. The Bcl-B protein modulates apoptosis. Bcl-B also binds Bcl-2. BCl-XL, and Bax but not Bak. Bcl-B displays a unique pattern of selectivity for binding and regulating the function of other members of the Bcl-2 family.Type: ApplicationFiled: April 20, 2009Publication date: December 10, 2009Inventors: John C. Reed, Ning Ke, Adam Godzik
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Publication number: 20090133136Abstract: An inducible siRNA expression polynucleotide and methods for its use are provided. The expression polynucleotide comprises a bicistronic expression cassette that encodes a repressor and a detectable marker, wherein the repressor controls expression of siRNA expression in the absence of an inducer.Type: ApplicationFiled: January 18, 2006Publication date: May 21, 2009Applicant: Immusol IncorporatedInventors: Demin Zhou, Jon E. Chatterton, Ning Ke, Jing Zhang, Joshua Bliesath, Henry Li, Flossie Wong-Staal
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Patent number: 7521548Abstract: A novel human member of the Bcl-2 family Bcl-B has been identified, which is closest in amino-acid sequence homology to the Boo (Diva) protein. The Bcl-B protein is widely expressed in adult human tissues. The Bcl-B protein modulates apoptosis. Bcl-B also binds Bcl-2, BCI-XL, and Bax but not Bak. Bcl-B displays a unique pattern of selectivity for binding and regulating the function of other members of the Bcl-2 family.Type: GrantFiled: February 7, 2002Date of Patent: April 21, 2009Assignee: Burnham Institute for Medical ResearchInventors: John C. Reed, Ning Ke, Adam Godzik
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Publication number: 20070184459Abstract: The present invention provides methods for identifying agents useful for inhibiting cancer cells by binding to various nuclear receptor proteins, or to the genes or RNA encoding such proteins.Type: ApplicationFiled: February 3, 2006Publication date: August 9, 2007Inventors: Henry Li, Ning Ke, Mirta Grifman, Gisela Claasen, Xiuyuan Hu, Kristen Defife, Cellia Habita, Wufang Fan, Kristina Rhoades, Philip Tan, Flossie Wong-Staal
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Publication number: 20070087984Abstract: The present invention is directed to methods of identifying agents useful for inhibiting cancer cells. The agents bind to one of the proteins described herein, or to a gene or mRNA encoding such protein. The invention is also directed to methods for inhibiting cancer cells by administering an agent that binds to one of the proteins described herein, or to a gene or mRNA encoding such protein.Type: ApplicationFiled: August 24, 2004Publication date: April 19, 2007Inventors: Xiuyuan Hu, Henry Li, Ning Ke, Mirta Grifman, Cheryl Rogers, Kristen Difife, Cellia Habita, Wufang Fan, Kristina Rhoades, Philip Tan, Richard Tritz, Flossie Wong-Staal
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Publication number: 20060234249Abstract: The present invention provides novel assays for assessing cancerous cell growth. The invention is useful for the identification and validation of oncogenes and tumor suppressors, as well as for the identification and validation of therapeutic compounds for the treatment of cancer.Type: ApplicationFiled: April 15, 2005Publication date: October 19, 2006Applicant: Immusol IncorporatedInventors: Ning Ke, De-Hua Yu, Aaron Albers, Gisela Claassen, Henry (Qi-Xiang) Li, Flossie Wong-Staal
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Publication number: 20050026172Abstract: Libraries for generating small interfering RNA (siRNA) are provided where the members of the library are optimized to inhibit the expression of genes that encode a predetermined family of proteins. The members of the library target at least mRNA encoding all members of the family of proteins. Methods for generating siRNA libraries of the present invention are also provided.Type: ApplicationFiled: February 10, 2004Publication date: February 3, 2005Applicant: Immusol, Inc.Inventors: Henry Li, Jon Chatterton, Wufang Fan, Ning Ke, Flossie Wong-Staal
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Publication number: 20040146858Abstract: The present invention relates to methods and compositions for the elucidation of gene function and the identification of novel genes. Specifically, the present invention relates to methods and compositions for improved functional genomic screening, functional inactivation of specific essential or non-essential genes, and identification of genes that are modulated in response to specific stimuli or encode recognizable phenotypic traits. In particular, the compositions of the present invention include, but are not limited to, expression cassettes comprising a novel dual promoter transcription system, that utilizes modified promoters, preferably containing complementary termination sequences, positioned across a coding sequence and in opposite orientation to each other. In addition, the present invention includes libraries comprising the expression cassettes of the invention, including vectors for transforming cells, such as replication-deficient retroviral vectors.Type: ApplicationFiled: July 23, 2003Publication date: July 29, 2004Applicant: Immusol, Inc.Inventors: Henry Li, Jon E. Chatterton, Ning Ke, Flossie Wong-Staal