Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: A light scanning device comprises a rotatable polygon-shaped structure comprising a frame, a plurality of mirror bonding plates configured to reflect light, and one or more flexures. At least some mirror bonding plates of the plurality of mirror bonding plates are adjustably attached to the frame based on corresponding flexures of the one or more flexures. A plurality of adjustment mechanisms is inserted between the frame and corresponding mirror bonding plates of the plurality of mirror bonding plates, where the plurality of adjustment mechanisms is configured to adjust tilt angles of the corresponding mirror bonding plates.

Abstract: A laser device for providing light to a LiDAR system comprises a plurality of seed lasers configured to provide multiple seed light beams, at least two of the seed light beams having different wavelengths. An amplifier is optically coupled to the plurality of seed lasers to receive the multiple seed light beams. A power pump is configured to provide pump power to the amplifier, where the amplifier amplifies the multiple seed light beams using the pump power to obtain amplified light beams. A second light coupling unit is configured to demultiplex the amplified light beams to obtain a plurality of output light beams, at least two of the output light beams having wavelengths corresponding to the wavelengths of the at least two seed light beams.

Abstract: The present invention relates to compositions and methods for improving the appearance of the skin. Compositions comprises at least water, glycerin, sodium PCA, erythritol, Carrageenan (Chondrus Crispus extract), xanthan Gum; hydrolyzed collagen, hexapeptide-9 and a physiologically acceptable medium. Methods comprise applying the compositions to the skin to improve the appearance of aging skin, increasing skin moisturization, refining skin pores and decreasing aging skin pigmentation defects.