Patents by Inventor Nissim Darvish
Nissim Darvish has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140067041Abstract: A flow reducing implant for reducing blood flow in a blood vessel having a cross sectional dimension, the flow reducing implant comprising a hollow element adapted for placement in the blood vessel defining a flow passage therethrough, said flow passage comprising at least two sections, one with a larger diameter and one with a smaller diameter, wherein said smaller diameter is smaller than a cross section of the blood vessel. A plurality of tabs anchor, generally parallel to the blood vessel wall, are provided in some embodiments of the invention.Type: ApplicationFiled: September 13, 2013Publication date: March 6, 2014Applicant: Neovasc Medical Ltd.Inventors: Shmuel Ben-Muvhar, IIan Shalev, Jonathan Tsehori, Nissim Darvish
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Patent number: 8655444Abstract: A method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart, comprising at least a portion having an activation, and applying a non-excitatory electric field having a given duration, at a delay after the activation, to the portion, which causes the force of contraction to be increased by a least 5%.Type: GrantFiled: October 29, 2012Date of Patent: February 18, 2014Assignee: Impulse Dynamics, N.V.Inventors: Shlomo Ben-Haim, Nissim Darvish, Maier Fenster, Yuval Mika
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Publication number: 20130317593Abstract: A method for deploying an expandable implant in a body passage of varying diameter includes selecting a balloon having a radial dimension that varies, when the balloon is inflated, in accordance with the varying diameter of the body passage. The balloon is inserted, in a deflated state, into the body passage, with the expandable implant fitted radially around the balloon. The balloon is inflated so as to cause the implant to open, responsively to the varying radial dimension of the balloon, into an expanded shape that approximately matches the varying diameter of the body passage, thus anchoring the implant in the body passage.Type: ApplicationFiled: November 12, 2012Publication date: November 28, 2013Applicant: NEOVASC MEDICAL LTD.Inventors: Shmuel Ben-Muvhar, Ilan Shalev, Jonathan Tsehori, Nissim Darvish
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Patent number: 8556954Abstract: Methods of using flow reducing implants for treatment of abnormal growths in the body are described. In embodiments of the claimed subject matter, a source blood vessel feeding the abnormal growth is first determined, and a flow reducing implant is then inserted into the source blood vessel to reduce the blood flow through the source blood vessel. The flow reducing implant includes at least one flared section for contacting a blood vessel wall, and at least one narrowed section defining a flow passage. Anchor tabs that lie generally in a plane of the flared section may also be employed.Type: GrantFiled: October 21, 2009Date of Patent: October 15, 2013Assignee: Neovasc Medical LtdInventors: Shmuel Ben Muvhar, Ilan Shalev, Jonathan Tsehori, Nissim Darvish
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Patent number: 8346363Abstract: A pancreatic controller, comprising: a glucose sensor, for sensing a level of glucose or insulin in a body serum; at least one electrode, for electrifying an insulin producing cell or group of cells; a power source for electrifying said electrode with a pulse that does not initiate an action potential in said cell and has an effect of increasing insulin secretion; and a controller which receives the sensed level and controls said power source to electrify said electrode to have a desired effect on said level.Type: GrantFiled: December 27, 2005Date of Patent: January 1, 2013Assignee: MetaCure LimitedInventors: Nissim Darvish, Tami Harel, Bella Felsen
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Patent number: 8321013Abstract: A method of modifying the force of contraction of at least a portion of a heart chamber is provided. A non-excitatory electric field of given duration is applied, at a delay after an activation of the heart, which increase the force of contraction by at least 5%. Apparatus is also provided for pacing with hemodynamic improvement. Circuitry applies an extended pacing signal to electrodes to pace the heart, the extended pacing signal having an overall duration greater than 8 ms from a time of initiation of application of that portion of the signal that initiates action potential propagation. The signal includes a train of biphasic pulses having pulse durations of at least 1 ms, and the signal has an amplitude that is at least three times as great as a threshold for pacing the heart and that is sufficient neither for cardioversion nor for defibrillation. Other embodiments are also described.Type: GrantFiled: October 31, 2007Date of Patent: November 27, 2012Assignee: Impulse Dynamics, N.V.Inventors: Nissim Darvish, Bella Felsen, Itzhak Shemer, Judith Kornfeld, Shlomo Ben-Haim, Maier Fenster, Yuval Mika
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Patent number: 8311629Abstract: A method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart, comprising at least a portion having an activation, and applying a non-excitatory electric field having a given duration, at a delay after the activation, to the portion, which causes the force of contraction to be increased by a least 5%.Type: GrantFiled: October 18, 2006Date of Patent: November 13, 2012Assignee: Impulse Dynamics, N.V.Inventors: Shlomo Ben-Haim, Nissim Darvish, Maier Fenster, Mike Yuval
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Patent number: 8306616Abstract: A method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart, comprising at least a portion having an activation, and applying a non-excitatory electric field having a given duration, at a delay after the activation, to the portion, which causes the force of contraction to be increased by a least 5%.Type: GrantFiled: October 31, 2007Date of Patent: November 6, 2012Assignee: Impulse Dynamics, N.V.Inventors: Shlomo Ben-Haim, Nissim Darvish, Maier Fenster, Mike Yuval
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Patent number: 8306617Abstract: A method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart, comprising at least a portion having an activation, and applying a non-excitatory electric field having a given duration, at a delay after the activation, to the portion, which causes the force of contraction to be increased by a least 5%.Type: GrantFiled: October 31, 2007Date of Patent: November 6, 2012Assignee: Impulse Dynamics N.V.Inventors: Shiomo Ben-Haim, Nissim Darvish, Maier Fenster, Mike Yuval
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Patent number: 8301247Abstract: A method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart, comprising at least a portion having an activation, and applying a non-excitatory electric field having a given duration, at a delay after the activation, to the portion, which causes the force of contraction to be increased by a least 5%.Type: GrantFiled: October 31, 2007Date of Patent: October 30, 2012Assignee: Impulse Dynamics, N.V.Inventors: Shlomo Ben-Haim, Nissim Darvish, Maier Fenster, Mika Yuval
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Patent number: 8260416Abstract: A method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart, comprising at least a portion having an activation, and applying a non-excitatory electric field having a given duration, at a delay after the activation, to the portion, which causes the force of contraction to be increased by a least 5%.Type: GrantFiled: October 31, 2007Date of Patent: September 4, 2012Assignee: Impulse Dynamics, N.V.Inventors: Shlomo Ben-Haim, Nissim Darvish, Maier Fenster, Mika Yuval
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Patent number: 8219201Abstract: An apparatus that comprises at least one electrode adapted to be placed adjacent to a portion of smooth muscle (200) and a controller for electrifying the electrode with a non-excitatory electric field (210) which does not generate excitation of the smooth muscle. The non-excitatory electric field affects the activity of the smooth muscle in a manner that controls a level of a chemical in the blood stream.Type: GrantFiled: April 17, 2007Date of Patent: July 10, 2012Assignee: Metacure LimitedInventors: Shlomo Ben-Haim, Nissim Darvish, Yuval Mika, Maier Fenster, Bella Felzen, Isaac Shemer
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Patent number: 8019421Abstract: A pancreatic controller, comprising: at least one electrode adapted for electrifying at least a portion of a pancreas; and a controller programmed to electrify said electrode so as to positively control at least the effect of at least two members of a group consisting of blood glucose level, blood insulin level and blood level of another pancreatic hormone. In one example, the controller controls insulin, glucagon and/or glucose blood levels.Type: GrantFiled: September 5, 2002Date of Patent: September 13, 2011Assignee: MetaCure LimitedInventors: Nissim Darvish, Tami Harel, Bella Felsen, Offer Glasberg
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Patent number: 8014858Abstract: Apparatus (18) is provided for defibrillating a heart (20) of a person. The apparatus (18) includes one or more electrodes (100) that are adapted to be coupled to the heart, and a control unit (90) that is adapted to drive the electrodes to apply electrical pulses to the heart at a rate which is typically greater than about 10 Hz. The control unit terminates the electrical pulses, so that the heart beats without fibrillation. Other embodiments are also described.Type: GrantFiled: May 25, 2000Date of Patent: September 6, 2011Assignee: Impulse Dynamics N.V.Inventors: Shlomo Ben-Haim, Nissim Darvish, Yuval Mika, Benny Rousso, Bella Felzen, Andre Routh
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Patent number: 7966071Abstract: A method of promoting the healing of a lesion in a smooth muscle (200), comprises selecting a smooth muscle portion having a lesion, and applying a non-excitory electric field (210) to the portion, which reduces the mechanical activity of the portion.Type: GrantFiled: October 31, 2007Date of Patent: June 21, 2011Assignee: Metacure LimitedInventors: Shlomo Ben-Haim, Nissim Darvish, Yuval Mika, Maier Fenster, Bella Felzen, Isaac Shemer
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Publication number: 20110112625Abstract: A method for deploying an expandable implant in a body passage of varying diameter includes selecting a balloon having a radial dimension that varies, when the balloon is inflated, in accordance with the varying diameter of the body passage. The balloon is inserted, in a deflated state, into the body passage, with the expandable implant fitted radially around the balloon. The balloon is inflated so as to cause the implant to open, responsively to the varying radial dimension of the balloon, into an expanded shape that approximately matches the varying diameter of the body passage, thus anchoring the implant in the body passage.Type: ApplicationFiled: May 27, 2010Publication date: May 12, 2011Applicant: NEOVASC MEDICAL LTD.Inventors: Shmuel Ben-Muvhar, Ilan Shalev, Jonathan Tsehori, Nissim Darvish
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Publication number: 20110029000Abstract: Disclosed is a suturing assembly for suturing in vivo tissue. The suturing assembly comprises a first suture thread positioned along a first surface of an in vivo tissue having a first surface and a second surface and at least one suture needle configured to pass through in vivo tissue. The suturing assembly additionally comprises a suture catch located on at least one side of the at least one suture needle, the suture catch configured to releasably catch the suture and draw the suture through the in vivo tissue during a first passage through the in vivo tissue such that the suture is formed into a first loop on a surface of the in vivo tissue.Type: ApplicationFiled: October 26, 2008Publication date: February 3, 2011Applicant: BLUE SURGICAL LTD.Inventors: Gilad Lavi, Eli Bar, Gil Griefner, Nissim Darvish
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Patent number: 7765008Abstract: A method of promoting the healing of a lesion in a smooth muscle (200), comprises selecting a smooth muscle portion having a lesion, and applying a non-excitory electric field (210) to the portion, which reduces the mechanical activity of the portion.Type: GrantFiled: October 31, 2007Date of Patent: July 27, 2010Assignee: Metacure LimitedInventors: Shlomo Ben-Haim, Nissim Darvish, Yuval Mika, Maier Fenster, Bella Felzen, Isaac Shemer
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Publication number: 20100114299Abstract: A flow reducing implant for reducing blood flow in a blood vessel having a cross sectional dimension, the flow reducing implant comprising a hollow element adapted for placement in the blood vessel defining a flow passage therethrough, said flow passage comprising at least two sections, one with a larger diameter and one with a smaller diameter, wherein said smaller diameter is smaller than a cross section of the blood vessel. A plurality of tabs anchor, generally parallel to the blood vessel wall, are provided in some embodiments of the invention.Type: ApplicationFiled: October 21, 2009Publication date: May 6, 2010Applicant: NEOVASC MEDICAL LTD.Inventors: Shmuel Ben Muvhar, Ilan Shalev, Jonathan Tsehori, Nissim Darvish
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Patent number: 7647102Abstract: A cardiac contractility modulating (CCM) device (30) includes an anti-arrhythmic therapy unit (38) for detecting a cardiac arrhythmia in a heart (2) of a patient based on processing electrical signals related to cardiac activity sensed at the heart, and for delivering anti-arrhythmic therapy to the heart. The device includes a cardiac contractility modulating (CCM) unit (40) capable of delivering cardiac contractility modulating (CCM) signals to the heart for modulating the contractility of a portion of the heart. The device may provide to the anti-arrhythmic therapy unit control signals associated with the delivery of the CCM signals to the heart. The control signals may be used to prevent interference of the CCM signals with the detecting of the cardiac arrhythmia. The device (30) includes a power source. The device may be an implantable device or a non-implantable device. The device may also include a pacing unit.Type: GrantFiled: November 18, 2005Date of Patent: January 12, 2010Assignee: Impulse Dynamics N.V.Inventors: Andre G. Routh, Edward Haluska, Nissim Darvish, David Prutchi, Ziv Belsky