Patents by Inventor Niv Antonovsky

Niv Antonovsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED AUTOTROPHIC BACTERIA FOR CO2 CONVERSION TO ORGANIC MATERIALS
    Publication number: 20240117386
    Abstract: A recombinant bacteria which is genetically modified to express formate dehydrogenase (FDH), phosphoribulokinase (prk) and Ribulose-Bisphosphate Carboxylase/oxygenase (RuBisCo) is disclosed. The bacteria may be modified to be autotrophic.
    Type: Application
    Filed: October 22, 2020
    Publication date: April 11, 2024
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Ron MILO, Shmuel GLEIZER, Niv ANTONOVSKY, Elad NOOR, Arren BAR-EVEN, Yehudit ZOHAR, Roee BEN NISSAN, Elad HERZ, Yinon Moise BAR-ON
  • RECOMBINANT MICROORGANISMS CAPABLE OF CARBON FIXATION
    Publication number: 20190211342
    Abstract: A microorganism which is genetically modified so that it produces a first essential biomass precursor by metabolizing CO2 using a recombinant carbon fixation enzyme is disclosed. The microorganism produces a second biomass precursor by metabolizing an organic carbon source and not by metabolizing CO2. The microorganism does not use the organic carbon source for producing the first essential biomass precursor.
    Type: Application
    Filed: March 25, 2019
    Publication date: July 11, 2019
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Ron MILO, Niv ANTONOVSKY, Elad NOOR, Arren BAR-EVEN, Yehudit ZOHAR, Lior ZELCBUCH, Shmuel GLEIZER, Shira AMRAM
  • Recombinant microorganisms capable of carbon fixation
    Patent number: 10294482
    Abstract: A microorganism which is genetically modified so that it produces a first essential biomass precursor by metabolizing CO2 using a recombinant carbon fixation enzyme is disclosed. The microorganism produces a second biomass precursor by metabolizing an organic carbon source and not by metabolizing CO2. The microorganism does not use the organic carbon source for producing the first essential biomass precursor.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: May 21, 2019
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Ron Milo, Niv Antonovsky, Elad Noor, Arren Bar-Even, Yehudit Zohar, Lior Zelcbuch, Shmuel Gleizer, Shira Amram
  • METHODS OF PRODUCTION OF PRODUCTS OF METABOLIC PATHWAYS
    Publication number: 20170268030
    Abstract: A plurality of isolated polynucleotide sequences encoding enzymes of the astaxanthin pathway is disclosed. The polynucleotides include: (i) a polynucleotide which encodes Phytoene dehydrogenase (crtI) and a first transcriptional regulatory sequence; (ii) a polynucleotide which encodes Beta-lycopene cyclase (lcy-B) and a second transcriptional regulatory sequence; (iii) a polynucleotide which encodes Beta-carotene ketolase (crtW) and a third transcriptional regulatory sequence; and wherein the first, second and third regulatory sequence are selected such that the expression of the Icy-B and the crtW is greater than a level of expression of the crtI. Methods of generating astaxanthin using the plurality of polynucleotide are also disclosed as well as bacterial cells comprising high levels of astaxanthin.
    Type: Application
    Filed: June 2, 2017
    Publication date: September 21, 2017
    Inventors: Ron MILO, Lior ZELCBUCH, Niv ANTONOVSKY
  • Methods of production of products of metabolic pathways
    Patent number: 9719122
    Abstract: A plurality of isolated polynucleotide sequences encoding enzymes of the astaxanthin pathway is disclosed. The polynucleotides include: (i) a polynucleotide which encodes Phytoene dehydrogenase (crtI) and a first transcriptional regulatory sequence; (ii) a polynucleotide which encodes Beta-lycopene cyclase (lcy-B) and a second transcriptional regulatory sequence; (iii) a polynucleotide which encodes Beta-carotene ketolase (crtW) and a third transcriptional regulatory sequence; and wherein the first, second and third regulatory sequence are selected such that the expression of the Icy-B and the crtW is greater than a level of expression of the crtI. Methods of generating astaxanthin using the plurality of polynucleotide are also disclosed as well as bacterial cells comprising high levels of astaxanthin.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: August 1, 2017
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Ron Milo, Lior Zelcbuch, Niv Antonovsky
  • RECOMBINANT MICROORGANISMS CAPABLE OF CARBON FIXATION
    Publication number: 20170183665
    Abstract: A microorganism which is genetically modified so that it produces a first essential biomass precursor by metabolizing CO2 using a recombinant carbon fixation enzyme is disclosed. The microorganism produces a second biomass precursor by metabolizing an organic carbon source and not by metabolizing CO2. The microorganism does not use the organic carbon source for producing the first essential biomass precursor.
    Type: Application
    Filed: May 21, 2015
    Publication date: June 29, 2017
    Inventors: Ron MILO, Niv ANTONOVSKY, Elad NOOR, Arren BAR-EVEN, Yehudit ZOHAR, Lior ZELCBUCH, Shmuel GLEIZER, Shira AMRAM
  • METHODS OF PRODUCTION OF PRODUCTS OF METABOLIC PATHWAYS
    Publication number: 20150211040
    Abstract: A plurality of isolated polynucleotide sequences encoding enzymes of the astaxanthin pathway is disclosed. The polynucleotides include: (i) a polynucleotide which encodes Phytoene dehydrogenase (crtI) and a first transcriptional regulatory sequence; (ii) a polynucleotide which encodes Beta-lycopene cyclase (lcy-B) and a second transcriptional regulatory sequence; (iii) a polynucleotide which encodes Beta-carotene ketolase (crtW) and a third transcriptional regulatory sequence; and wherein the first, second and third regulatory sequence are selected such that the expression of the Icy-B and the crtW is greater than a level of expression of the crtI. Methods of generating astaxanthin using the plurality of polynucleotide are also disclosed as well as bacterial cells comprising high levels of astaxanthin.
    Type: Application
    Filed: July 17, 2013
    Publication date: July 30, 2015
    Inventors: Ron Milo, Lior Zelcbuch, Niv Antonovsky