Patents by Inventor Noah Palm

Noah Palm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETING HOST-BACTERIA INTERACTIONS FOR THE TREATMENT OF MICROBIOTA-MEDIATED DISEASES
    Publication number: 20230407291
    Abstract: The present invention generally relates to compositions and methods for modulating specific paired host protein-microbiota interactions and the use thereof for the prevention and treatment of diseases and disorders.
    Type: Application
    Filed: November 17, 2021
    Publication date: December 21, 2023
    Inventors: Connor Rosen, Noah Palm, Aaron Ring
  • Basehit, a high-throughput assay to identify proteins involved in host-microbe interaction
    Patent number: 11668021
    Abstract: The invention provides a BASEHIT screening method for identifying proteins that are involved in host-microbe interactions which may function as therapeutic targets.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: June 6, 2023
    Assignee: YALE UNIVERSITY
    Inventors: Connor Rosen, Noah Palm, Aaron Ring
  • MICROBIOTA METABOLITES THAT SHAPE HOST PHYSIOLOGY
    Publication number: 20230043198
    Abstract: Methods of identifying test compounds or mixtures of test compounds from microbiota that bind to a fusion protein, such as a G-protein coupled receptor, are described. Also described are methods for high throughput screening of microbiota metabolites that are capable of activating G-protein coupled receptors.
    Type: Application
    Filed: December 9, 2019
    Publication date: February 9, 2023
    Applicant: Yale University
    Inventors: Noah PALM, Aaron RING, Haiwei CHEN
  • Compositions and methods for identifying secretory antibody-bound microbes
    Patent number: 11299790
    Abstract: The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: April 12, 2022
    Assignee: Yale University
    Inventors: Richard Flavell, Noah Palm, Marcel de Zoete
  • COMPOSITIONS AND METHODS FOR TREATING AN INFLAMMATORY DISEASE OR DISORDER
    Publication number: 20210170014
    Abstract: The invention relates to compositions and methods for treating inflammatory diseases and disorders in a subject in need thereof. In certain aspects, the invention relates to immunogenic compositions (e.g., vaccines) to diminish the number or pathogenic effects of one or more bacteria associated with the development or progression of an inflammatory disease or disorder.
    Type: Application
    Filed: February 18, 2021
    Publication date: June 10, 2021
    Inventors: Richard Flavell, Noah Palm, Marcel De Zoete
  • BASEHIT, a high-throughput assay to identify proteins involved in host-microbe interaction
    Publication number: 20210079558
    Abstract: The invention provides a BASEHIT screening method for identifying proteins that are involved in host-microbe interactions which may function as therapeutic targets.
    Type: Application
    Filed: May 9, 2018
    Publication date: March 18, 2021
    Inventors: Connor Rosen, Noah Palm, Aaron Ring
  • Compositions and methods for treating an inflammatory disease or disorder
    Patent number: 10925953
    Abstract: The invention relates to compositions and methods for treating inflammatory diseases and disorders in a subject in need thereof. In certain aspects, the invention relates to immunogenic compositions (e.g., vaccines) to diminish the number or pathogenic effects of one or more bacteria associated with the development or progression of an inflammatory disease or disorder.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: February 23, 2021
    Assignee: Yale University
    Inventors: Richard Flavell, Noah Palm, Marcel De Zoete
  • Compositions and Methods for Identifying Secretory Antibody-Bound Microbes
    Publication number: 20200370098
    Abstract: The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Application
    Filed: August 14, 2020
    Publication date: November 26, 2020
    Inventors: Richard Flavell, Noah Palm, Marcel de Zoete
  • Compositions and methods for identifying secretory antibody-bound microbes
    Patent number: 10774392
    Abstract: The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: September 15, 2020
    Assignee: Yale University
    Inventors: Richard Flavell, Noah Palm, Marcel de Zoete
  • Compositions and Methods for Identifying Secretory Antibody-Bound Microbes
    Publication number: 20200002751
    Abstract: The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Application
    Filed: August 14, 2019
    Publication date: January 2, 2020
    Inventors: Richard Flavell, Noah Palm, Marcel de Zoete
  • Compositions and methods for identifying secretory antibody-bound microbes
    Patent number: 10428392
    Abstract: The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: October 1, 2019
    Assignee: YALE UNIVERSITY
    Inventors: Richard Flavell, Noah Palm, Marcel de Zoete
  • Compositions and Methods for Treating an Inflammatory Disease or Disorder
    Publication number: 20190083599
    Abstract: The invention relates to compositions and methods for treating inflammatory diseases and disorders in a subject in need thereof. In certain aspects, the invention relates to immunogenic compositions (e.g., vaccines) to diminish the number or pathogenic effects of one or more bacteria associated with the development or progression of an inflammatory disease or disorder.
    Type: Application
    Filed: August 28, 2015
    Publication date: March 21, 2019
    Inventors: Richard Flavell, Noah Palm, Marcel De Zoete
  • Compositions and methods for identifying secretory antibody-bound microbes
    Publication number: 20180030517
    Abstract: The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Application
    Filed: July 31, 2017
    Publication date: February 1, 2018
    Inventors: Richard Flavell, Noah Palm, Marcel de Zoete
  • Compositions and methods for identifying secretory antibody-bound microbes
    Patent number: 9758838
    Abstract: The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: September 12, 2017
    Assignee: YALE UNIVERSITY
    Inventors: Richard Flavell, Noah Palm, Marcel de Zoete
  • Compositions and Methods for Identifying Secretory Antibody-Bound Microbes
    Publication number: 20160017409
    Abstract: The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Application
    Filed: March 12, 2014
    Publication date: January 21, 2016
    Inventors: Richard Flavell, Noah Palm, Marcel de Zoete