Patents by Inventor Nobuhiko Hayakawa

Nobuhiko Hayakawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIGONUCLEOTIDE PRODUCTION METHOD
    Publication number: 20240018180
    Abstract: Oxidizing an oligonucleotide precursor having a phosphite ester bond or a phosphonate ester bond with an oxidant, wherein the oxidant is a compound represented by the formula (I) excluding 2,2-dipyridyl disulfide: wherein the symbols are as defined in the specification is useful for producing an oligonucleotide having a phosphate ester bond.
    Type: Application
    Filed: August 11, 2023
    Publication date: January 18, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Nobuhiko HAYAKAWA, Taisuke ICHIMARU, Satoshi INOUE, Daisuke TAKAHASHI
  • Substituted benzenesulfonamides as inhibitors of alpha-4 beta-7 integrin activity
    Patent number: 10562898
    Abstract: Provided is a compound having ?4 integrin inhibitory action. The compound is a sulfonamide derivative represented by the following formula (I), or pharmaceutically acceptable salt thereof: where R1 to R5, e to h, D, and B represent those as described in the specification.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: February 18, 2020
    Assignee: EA PHARMA CO., LTD.
    Inventors: Munetaka Tokumasu, Masatsugu Noguchi, Mizuki Kawahira, Kana Iwasaki, Nobuhiko Hayakawa, Wataru Miyanaga, Yuki Saitou, Yui Yamaura, Ayatoshi Ando, Atsushi Tsuruta, Misato Noguchi
  • SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
    Publication number: 20190040059
    Abstract: Provided is a compound having ?4 integrin inhibitory action. The compound is a sulfonamide derivative represented by the following formula (I), or pharmaceutically acceptable salt thereof: where R1 to R5, e to h, D, and B represent those as described in the specification.
    Type: Application
    Filed: February 6, 2017
    Publication date: February 7, 2019
    Applicant: EA PHARMA CO., LTD.
    Inventors: Munetaka TOKUMASU, Masatsugu NOGUCHI, Mizuki KAWAHIRA, Kana IWASAKI, Nobuhiko HAYAKAWA, Wataru MIYANAGA, Yuki SAITOU, Yui YAMAURA, Ayatoshi ANDO, Atsushi TSURUTA, Misto NOGUCHI
  • IMIDAZOPYRIDAZINE COMPOUNDS
    Publication number: 20120323002
    Abstract: By searching various compounds having an inhibiting activity against IL-12/IL-23 production, the present invention provides a pharmaceutical composition or a therapeutic or preventive agent for diseases related to IL-12/IL-23 excessive production each of which comprises the compound(s) of the present invention. More specifically, the present invention provides an imidazopyridazine compound having an inhibiting activity against IL-12/IL-23 production or pharmaceutically acceptable salts thereof; and a useful pharmaceutical composition or a useful therapeutic or preventive agent for diseases related to IL-12/IL-23 excessive production each of which comprises said compound or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: June 25, 2012
    Publication date: December 20, 2012
    Applicant: AJINOMOTO CO., INC.
    Inventors: Takashi YAMAMOTO, Ayatoshi ANDO, Nobuhiko HAYAKAWA, Masatsugu NOGUCHI, Hikaru NISHIO, Agung EVIRYANTI, Ryohei YOKOYAMA, Shunsuke KAGEYAMA, Kanna KURIBAYASHI
  • Pyrazolo-pyrimidine compounds
    Patent number: 8314098
    Abstract: The present invention has searched for a variety of compounds which show IL-12/IL-23 production-inhibitory activities and herein provides a pharmaceutical composition and an agent for preventing or treating IL-12/IL-23 excess production-related diseases, which comprise the compound.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: November 20, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Takashi Yamamoto, Ayatoshi Andou, Nobuhiko Hayakawa, Masatsugu Noguchi, Kanna Kuribayashi, Agung Eviryanti, Ryohei Yokoyama, Shunsuke Fukuda, Toshihiko Sugiura, Shunsuke Kageyama, Yoichiro Shima, Misato Noguchi
  • PYRAZOLO-PYRIMIDINE COMPOUNDS
    Publication number: 20110294781
    Abstract: The present invention has searched for a variety of compounds which show IL-12/IL-23 production-inhibitory activities and herein provides a pharmaceutical composition and an agent for preventing or treating IL-12/IL-23 excess production-related diseases, which comprise the compound.
    Type: Application
    Filed: June 27, 2011
    Publication date: December 1, 2011
    Applicant: AJINOMOTO CO., INC.
    Inventors: Takashi YAMAMOTO, Ayatoshi Andou, Nobuhiko Hayakawa, Masatsugu Noguchi, Kanna Kuribayashi, Agung Eviryanti, Ryohei Yokoyama, Shunsuke Fukuda, Toshihiko Sugiura, Shunsuke Kageyama, Yoichiro Shima, Misato Noguchi