Patents by Inventor Nobuhiko Kayagaki

Nobuhiko Kayagaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-CLEAVED ICASPASE SUBSTRATE ANTIBODIES AND METHODS OF USE
    Publication number: 20230399417
    Abstract: Provided herein are antibodies that bind to cleaved inflammatory caspase (iCaspase) substrates and methods of screening for such antibodies. Also provided herein are detection methods using such antibodies for detecting a cleaved iCaspase substrate.
    Type: Application
    Filed: April 14, 2023
    Publication date: December 14, 2023
    Inventors: Christopher W. DAVIES, Nobuhiko KAYAGAKI, James T. KOERBER
  • METHODS AND COMPOSITIONS FOR TARGETING RELT
    Publication number: 20080057066
    Abstract: Anti-RELT monoclonal antibodies, and methods for using the antibodies, are provided. Methods of using RELT polypeptides and nucleic acids in modulating immune cell development and in modulating cytokine production are also provided.
    Type: Application
    Filed: February 12, 2007
    Publication date: March 6, 2008
    Inventors: Vishva Dixit, Nobuhiko Kayagaki, Yan Wu
  • Monoclonal antibody reacting specifically reacting with Fas ligand and production process thereof
    Patent number: 6946255
    Abstract: The invention provides monoclonal antibodies, which specifically react with a Fas ligand, or active fragments thereof, a production process of the monoclonal antibodies, which specifically react with a Fas ligand, hybridomas separately producing a monoclonal antibody, which specifically reacts with a Fas ligand present on a cell surface, a method of detecting a Fas ligand in a solution, and a kit for use in detecting a Fas ligand, comprising plurality of monoclonal antibodies against Fas ligand in combination.
    Type: Grant
    Filed: March 21, 1996
    Date of Patent: September 20, 2005
    Assignee: Ko Okumura
    Inventors: Nobuhiko Kayagaki, Hideo Yagita, Ko Okumura, Motomi Nakata
  • Antibodies to Fas-L for treatment of hepatitis
    Patent number: 6068841
    Abstract: The invention provides therapeutic agents for hepatitis, comprising an antibody against a human Fas ligand, or an active fragment thereof as an active ingredient. The therapeutic agents for hepatitis according to the invention are particularly effective for the treatment of hepatitis caused by the death of hepatocytes due to apoptosis among many kinds of hepatitis.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: May 30, 2000
    Assignee: Sumitomo Electric Industries, Ltd.
    Inventors: Ken-ichiro Seino, Nobuhiko Kayagaki, Hideo Yagita, Ko Okumura, Motomi Nakata