Patents by Inventor Nobuhisa Watanabe

Nobuhisa Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6218392
    Abstract: A fused pyridazine compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof which exhibits an inhibitory activity against cyclic GMP phosphodiesterase (hereinafter referred to as “cGMP-PDE”). The compounds are useful as preventive and therapeutic agents for diseases for which a cGMP-PDE inhibiting action is efficacious, for example, ischemic heart diseases such as angina pectoris, myocardial infarct and chronic and acute cardiac failure, pulmonary hypertension, arteriosclerosis and bronchial asthma.
    Type: Grant
    Filed: September 29, 1998
    Date of Patent: April 17, 2001
    Assignee: Eisai Co., Ltd.
    Inventors: Nobuhisa Watanabe, Yasuhiro Kabasawa, Yasutaka Takase, Fumihiro Ozaki, Keiji Ishibashi, Kazuki Miyazaki, Masayuki Matsukura, Shigeru Souda, Kazutoshi Miyake, Hiroki Ishihara, Kohtaro Kodama, Hideyuki Adachi
  • Patent number: 5854745
    Abstract: When an electronic component is picked up at an electronic component feeding part and then positioned and mounted at a predetermined mounting position on a transparent panel, mounting position marks formed at the mounting position on the transparent panel are registered with positioning marks formed on the electronic component, to thereby recognize the relative position from a surface opposite to a surface of the transparent panel where the electronic component is to be mounted, so that the position of the electronic component is corrected based on the result of the recognition before the electronic component is mounted at the predetermined mounting position on the transparent panel.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: December 29, 1998
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Nobuhiko Muraoka, Shinji Kanayama, Shinzo Eguchi, Masaru Ichihara, Shuichi Hirata, Nobuhisa Watanabe
  • Patent number: 5849741
    Abstract: A fused pyridazine compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof which exhibits an inhibitory activity against cyclic GMP phosphodiesterase (hereinafter referred to as "cGMP-PDE").The compounds are useful as preventive and therapeutic agents for diseases for which a cGMP-PDE inhibiting action is efficacious, for example, ischemic heart diseases such as angina pectoris, myocardial infarct and chronic and acute cardiac failure, pulmonary hypertension, arteriosclerosis and bronchial asthma.
    Type: Grant
    Filed: April 9, 1996
    Date of Patent: December 15, 1998
    Assignee: Eisai Co., Ltd.
    Inventors: Nobuhisa Watanabe, Yasuhiro Kabasawa, Yasutaka Takase, Fumihiro Ozaki, Keiji Ishibashi, Kazuki Miyazaki, Masayuki Matsukura, Shigeru Souda, Kazutoshi Miyake, Hiroki Ishihara, Kohtaro Kodama, Hideyuki Adachi
  • Patent number: 5833723
    Abstract: In a hydrogen generating apparatus comprising a housing (10) in which a catalyst (11) is filled up into an inner space (10a), a supplying tube (12) opening to the inner space, a blowing tube (14) by which a reformed gas generated in the inner space with reacting is removed from the inner space, the methanol supplying means (20, 21) connected to the supplying tube and the oxygen supplying means (30, 31, 32) connected to the supplying tube, the heating means (13) placed in near an opening part of the supplying tube are provided and when starting, a time period for obtaining the sufficient amounts of hydrogen generated can be shorten.
    Type: Grant
    Filed: November 15, 1996
    Date of Patent: November 10, 1998
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Yasuo Kuwabara, Hiroshige Ota, Akira Matsuoka, Takumi Hayashi, Nobuhisa Watanabe
  • Patent number: 5801180
    Abstract: The present invention provides a nitrogenous heterocyclic compound represented by the following general formula (1) or a pharmacologically acceptable salt thereof which is useful for various ischemic heart diseases and the like: ##STR1## ?in formula (1), ring A represents a benzene ring, a pyridine ring or a cyclohexane ring; ring B represents a pyridine ring, a pyrimidine ring or an imidazole ring, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent each a hydrogen atom, a halogen atom or a group such as a lower alkoxy group; R.sup.5 represents a group represented by the formula --NR.sup.11 R.sup.12 (wherein R.sup.11 and R.sup.12 represent each a hydrogen atom or a group such as a lower alkyl group) or the like; and R.sup.6 represents a group represented by the formula ##STR2## (wherein R.sup.19 represents a hydrogen atom, a lower alkyl group or the like; R.sup.20, R.sup.21 and R.sup.22 represent each a hydrogen atom, a halogen atom, a hydroxyl group or the like; and r represents 0 or an integer of 1 to 8)!.
    Type: Grant
    Filed: July 31, 1997
    Date of Patent: September 1, 1998
    Assignee: Eisai Co., Ltd.
    Inventors: Yasutaka Takase, Nobuhisa Watanabe, Makoto Matsui, Hironori Ikuta, Teiji Kimura, Takao Saeki, Hideyuki Adachi, Tadakazu Tokumura, Hisatoshi Mochida, Yasunori Akita, Shigeru Souda
  • Patent number: 5713125
    Abstract: Electronic parts are mounted onto a substrate. A parts supply device holds a plurality of electronic parts and moves to be positioned at a predetermined parts take-out position. The parts supply device includes a readable and writable memory for storing data indicative of the plurality of electronic parts held therein. A reading device reads the data stored in the readable and writable memory provided in the parts supply device when the parts supply device moves relative to the reading device to the predetermined parts take-out position. The electronic part is extracted from the parts supply device position at the predetermined parts take-out position and mounted on a substrate.
    Type: Grant
    Filed: January 4, 1995
    Date of Patent: February 3, 1998
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Nobuhisa Watanabe, Masatoshi Yanagawa, Noriaki Yoshida, Takashi Noyama, Masao Iritani, Shinji Morimoto
  • Patent number: 5707998
    Abstract: The present invention relates to a nitrogen-containing heterocyclic compound exhibiting an inhibitory activity against cGMP-PDE. The compound represented by the formula (I) or a pharmacologically acceptable salt thereof: ##STR1## wherein R.sup.1 represents a group represented by the formula: --NR.sup.4 R.sup.5 (wherein R.sup.4 and R.sup.5 each represent hydrogen, lower alkyl or the like) or the like; R.sup.2 represents a group represented by the formula: ##STR2## (wherein R.sup.8 represents a carboxyl group which may be protected, or the like) or the like; and R.sup.3 represents a group represented by the formula: ##STR3## (wherein R.sup.6 and R.sup.7 each represent hydrogen, lower alkyl or the like) or the like.
    Type: Grant
    Filed: September 25, 1995
    Date of Patent: January 13, 1998
    Assignee: Eisai Co., Ltd.
    Inventors: Yasutaka Takase, Nobuhisa Watanabe, Hideyuki Adachi, Kohtaro Kodama, Hiroki Ishihara, Takao Saeki, Shigeru Souda
  • Patent number: 5693652
    Abstract: The present invention provides a nitrogenous heterocyclic compound represented by the following general formula (1) or a pharmacologically acceptable salt thereof which is useful for various ischemic heart diseases and the like: ##STR1## ?in formula (1), ring A represents a benzene ring, a pyridine ring or a cyclohexane ring: ring B represents a pyridine ring, a pyrimidine ring or an imidazole ring, R.sup.1, R.sup.2, R.sup.3 R.sup.4, R.sup.5 and R.sup.6 are described herein.
    Type: Grant
    Filed: March 23, 1995
    Date of Patent: December 2, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Yasutaka Takase, Nobuhisa Watanabe, Makoto Matsui, Hironori Ikuta, Teiji Kimura, Takao Saeki, Hideyuki Adachi, Tadakazu Tokumura, Hisatoshi Mochida, Yasunori Akita, Shigeru Souda
  • Patent number: 5679304
    Abstract: A method of manufacturing a panel button includes providing a molding die including a transferable molding die defining a cavity, a core molding die having a runner, a sprue and a gate and a stationary molding die having a sprue. A hollow space is provided in a bottom of the cavity wherein a push button is formed. A projecting portion is inserted into the cavity and is formed on the underside of the core molding die. Two hollow coaxial spaces are connected to each other, one to form a boss, the other to form an elastic arm. A plastic sheet is introduced into the cavity and is sandwiched between the transferable molding die and the core molding die. The plastic sheet has an unbonding portion at a position where the push button is to be formed. A molten resin material is injected into the cavity through the runner, sprue and gate. The thus formed panel button includes the push button on the plastic sheet.
    Type: Grant
    Filed: February 1, 1995
    Date of Patent: October 21, 1997
    Assignee: Yoshida Industry Co., Ltd.
    Inventors: Nobuhisa Watanabe, Mikihiro Kuramitsu
  • Patent number: 5667129
    Abstract: An IC component mounting method includes sucking each of different types of IC components at a supply position to which the IC component having an electrode-provided face thereof to be bonded to a circuit board, recognizing an image of the IC component to detect a sucking position at which a sucking nozzle does not interfere with an electrode of the IC component, detecting a height of the sucking position, positioning the sucking nozzle at the sucking position while the position of the sucking nozzle in a vertical direction is controlled, sucking the IC component by a mounting head, recognizing a position of the IC component sucked by the mounting head, and recognizing a reference position of the circuit board or an IC component-mounting position thereof, and positioning the IC component at the IC component-mounting position of the circuit board and then mounting the IC component on the circuit board.
    Type: Grant
    Filed: May 1, 1995
    Date of Patent: September 16, 1997
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Koichi Morita, Yoshihiko Misawa, Keiji Saeki, Akira Kabeshita, Nobuhisa Watanabe
  • Patent number: 5668136
    Abstract: A benzene, pyridine or pyrimidine derivative having the below shown formula is novel and useful as an anti-arteriosclerotic agent. ##STR1## wherein R.sup.1 stands for a lower alkyl group, an amino group which may be substituted, or the like; R.sup.2 stands for a group represented by the formula: ##STR2## (wherein R.sup.16 stands for an alkyl group having 1 to 6 carbon atoms, or the like) or the like; R.sup.3 stands for a group represented by the formula: --O--(CH.sub.2).sub.m --Y (Y stands for an imidazolyl or piperazinyl group, or the like and m is 1 to 6) or the like; R.sup.5 stands for a hydrogen atom, a lower alkyl group, or the like; A stands for a group represented by the formula: ##STR3## (wherein R.sup.6 stands for a hydrogen atom, a lower alkyl group, or the like), --N.dbd., or the like; and B stands for a group represented by the formula: ##STR4## (wherein R.sup.4 stands for a hydrogen or the like), --N.dbd., or the like.
    Type: Grant
    Filed: September 11, 1991
    Date of Patent: September 16, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Teiji Kimura, Nobuhisa Watanabe, Yasutaka Takase, Kenji Hayashi, Makoto Matsui, Hironori Ikuta, Youji Yamagishi, Kozo Akasaka, Hiroshi Tanaka, Issei Ohtsuka, Takao Saeki, Motoji Kogushi, Tohru Fujimori, Isao Saito
  • Patent number: 5630085
    Abstract: A microcomputer includes an instruction decoder and a program counter. The instruction decoder decodes fetched instructions and outputs a control signal ordering execution of the fetched instruction. The control signal from the instruction decoder includes a component controlling fetch cycles which triggers a fetch cycle at the beginning of each instruction cycle to fetch the operand for the instruction currently being executed and midway through each instruction cycle to fetch the OP code for the next instruction. The program counter is responsive to the triggering of each fetch cycle to increment its counter value so as to keep the counter value consistent with the address being accessed in each fetch cycle.
    Type: Grant
    Filed: June 28, 1993
    Date of Patent: May 13, 1997
    Assignee: Sony Corporation
    Inventor: Nobuhisa Watanabe
  • Patent number: 5621907
    Abstract: A microcomputer includes an instruction decoder and a program counter. The instruction decoder decodes fetched instructions and outputs a control signal ordering execution of the fetched instruction. The control signal from the instruction decoder includes a component controlling fetch cycles which triggers a fetch cycle at the beginning of each instruction cycle to fetch the operand for the instruction currently being executed and midway through each instruction cycle to fetch the OP code for the next instruction. The program counter is responsive to the triggering of each fetch cycle to increment its counter value so as to keep the counter value consistent with the address being accessed in each fetch cycle.
    Type: Grant
    Filed: February 1, 1995
    Date of Patent: April 15, 1997
    Assignee: Sony Corporation
    Inventor: Nobuhisa Watanabe
  • Patent number: 5614627
    Abstract: It relates to a quinazoline compound useful as a medicine exhibiting an inhibitory action on calmodulin-dependent cGMP-PDE.A quinazoline compound represented by the general formula (I) or a pharmacologically acceptable salt thereof: ##STR1## (wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 may be the same or different from each other and each represents a hydrogen atom, a lower alkyl group or the like; and R.sup.6 and R.sup.7 may be the same or different from each other and each represents a hydrogen atom, a carboxyl alkyl group or the like).
    Type: Grant
    Filed: June 27, 1995
    Date of Patent: March 25, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Yasutaka Takase, Nobuhisa Watanabe, Hideyuki Adachi, Kohtaro Kodama, Hiroki Ishihara, Takao Saeki, Shigeru Souda
  • Patent number: 5576322
    Abstract: The invention is directed to certain 2,4-diaminoquinazoline compounds, their pharmaceutically acceptable salts, the pharmaceutical compositions comprising those compounds and their therapeutic methods of use. The compounds possess anti-ischemic activity.
    Type: Grant
    Filed: February 18, 1994
    Date of Patent: November 19, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Yasutaka Takase, Nobuhisa Watanabe, Makoto Matsui, Hironori Ikuta, Teiji Kimura, Takao Saeki, Hideyuki Adachi, Tadakazu Tokumura, Hisatoshi Mochida, Yasunori Akita, Shigeru Souda
  • Patent number: 5575059
    Abstract: A TCP mounting apparatus includes a tool storing and holding section having arranged therein a plurality of different kinds of bonding tools which suction tape carrier packages of respective different shapes to heat and pressure bond the tape carrier packages to a liquid crystal panel. The bonding tools are stored at predetermined positions within the tool storing and holding section, and the tool storing and holding section includes a heater for heating the stored and held bonding tools and detector for detecting a presence and absence of the stored bonding tools at each position. A head part is also provided for extracting any selected one of the bonding tools stored and held in the tool storing and holding section. The head part also includes a heater for heating an extracted bonding tool. A conveyor mechanism moves and positions the head part to the predetermined positions of the tool storing and holding section.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: November 19, 1996
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Nobuhiko Muraoka, Nobuhisa Watanabe, Shinjiro Tsuji, Ikuko Obata
  • Patent number: 5462958
    Abstract: The present invention provides a novel benzene derivative useful as a preventive and medically treating medicine for arteriosclerosis, and a cholesterol O-acyl transferase inhibitor comprising the benzene derivative as an active ingredient.The benzene derivative according to the present invention is represented by the following general formula (I): ##STR1## wherein R.sup.1 represents a carboxyl group which may be protected or a group represented by the formula: ##STR2## wherein R.sup.5 represents a lower alkyl group or a hydroxyalkyl group and R.sup.6 represents a hydrogen atom or a hydroxyl group; R.sup.2 represents a hydrogen atom, a lower alkyl group or the like; R.sup.3 and R.sup.4 each represent a hydrogen atom or a hydroxyl group; and p is an integer of 1 to 6.
    Type: Grant
    Filed: May 19, 1994
    Date of Patent: October 31, 1995
    Assignee: Eisai Co., Ltd.
    Inventors: Kenji Hayashi, Nobuhisa Watanabe, Koichi Nose, Hiroshi Tanaka, Issei Ohtsuka, Motoji Kokushi, Hironobu Hiyoshi, Hiroko Kobayashi, Toshie Yamada, Toru Horie
  • Patent number: 5400497
    Abstract: An apparatus is for mounting electronic parts onto a substrate. The apparatus includes a parts supply device for holding a plurality of electronic parts and for moving to be positioned at a predetermined parts take-out position. The parts supply device includes a readable and writable memory for storing data indicative of the plurality of electronic parts held therein. The apparatus further includes a reading device for reading the data stored in the readable and writable memory provided in the parts supply device when the parts supply device moves relative to the reading device to the predetermined parts take-out position. The electronic part is extracted from the parts supply device position at the predetermined parts take-out position and mounted on a substrate.
    Type: Grant
    Filed: June 4, 1993
    Date of Patent: March 28, 1995
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Nobuhisa Watanabe, Masatoshi Yanagawa, Noriaki Yoshida, Takashi Noyama, Masao Iritani, Shinji Morimoto
  • Patent number: 5167031
    Abstract: A clock pulse generator for a one-chip microprocessor permits the microprocessor to be operated on two different power sources by effectively using a single source of clock pulses, a clock pulse divider and gate circuits to gate a specific sequence of pulses to the microprocessor. The period of a slowest clock pulse signal after division is integrally related to the periods of the faster clock pulse signals so that the pulse signals are synchronously provided.
    Type: Grant
    Filed: May 10, 1988
    Date of Patent: November 24, 1992
    Assignee: Sony Corporation
    Inventor: Nobuhisa Watanabe
  • Patent number: 5157772
    Abstract: To speed up data transfer, one embodiment of the invention features a transmission gate arrangement which pre-charges and transfers data in internal and external buses with the same timing and which further initializes the internal bus and a device such as an ALU, every bus cycle. A second embodiment speeds the data transfer in the buses by providing two data transfer paths through the interconnected buses and reducing the combined resistances of the internal and external buses.
    Type: Grant
    Filed: May 10, 1988
    Date of Patent: October 20, 1992
    Assignee: Sony Corporation
    Inventor: Nobuhisa Watanabe