Patents by Inventor Nobutaka Oohata

Nobutaka Oohata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic lipopeptide acylase
    Patent number: 6825003
    Abstract: The present invention provides a cyclic lipopeptide acylase which may effectively deacylate the acyl side chain of a cyclic lipopeptide compound, specifically FR901379 Substance or its analog thereof shown by the following general formula [I], and a process for production of a cyclic peptide compound which comprises the use of said acylase.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: November 30, 2004
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Satoshi Ueda, Miho Tanaka, Masami Ezaki, Kazutoshi Sakamoto, Seiji Hashimoto, Nobutaka Oohata, Masaru Tsuboi, Michio Yamashita
  • Process for the deacylation of cyclic lipopeptides
    Patent number: 6573084
    Abstract: There is provided a cyclic lipopeptide acylase which is capable of deacylating the acyl side chain of a cyclic lipopeptide compound, e.g. Substance FR901379 or its analog, of the following general formula [I] with effectiveness as well a method of producing a cyclic peptide compound which comprises using the acylase. [wherein R1 is acyl; R2 is hydroxy or acyloxy; R3 is hydrogen or hydroxy; R4 is hydrogen or hydroxy; R5 is hydrogen or hydroxysulfonyloxy; and R6 is hydrogen or carbamoyl.
    Type: Grant
    Filed: September 6, 2000
    Date of Patent: June 3, 2003
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Satoshi Ueda, Miho Tanaka, Masami Ezaki, Kazutoshi Sakamoto, Seiji Hashimoto, Nobutaka Oohata, Masaru Tsuboi, Michio Yamashita
  • Process for the deacylation of cyclic lipopeptides
    Patent number: 6537789
    Abstract: There is provided a cyclic lipopeptide acylase which is capable of deacylating the acyl side chain of a cyclic lipopeptide compound, e.g. Substance FR901379 or its analog, of the following general formula [I] with effectiveness as well a method of producing a cyclic peptide compound which comprises using the acylase. [wherein R1 is acyl; R2 is hydroxy or acyloxy; R3 is hydrogen or hydroxy; R4 is hydrogen or hydroxy; R5 is hydrogen or hydroxysulfonyloxy; and R6 is hydrogen or carbamoyl.
    Type: Grant
    Filed: September 6, 2000
    Date of Patent: March 25, 2003
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Satoshi Ueda, Miho Tanaka, Masami Ezaki, Kazutoshi Sakamoto, Seiji Hashimoto, Nobutaka Oohata, Masaru Tsuboi, Michio Yamashita
  • Cyclic lipopeptide acylase
    Publication number: 20020115133
    Abstract: The present invention provides a cyclic lipopeptide acylase which may effectively deacylate the acyl side chain of a cyclic lipopeptide compound, specifically FR901379 Substance or its analog thereof shown by the following general formula [I], and a process for production of a cyclic peptide compound which comprises the use of said acylase.
    Type: Application
    Filed: January 18, 2002
    Publication date: August 22, 2002
    Applicant: Fujisawa Pharmaceutical Co. Ltd.
    Inventors: Satoshi Ueda, Miho Tanaka, Masami Ezaki, Kazutoshi Sakamoto, Seiji Hashimoto, Nobutaka Oohata, Masaru Tsuboi, Michio Yamashita
  • Cyclic lipopeptide acylase
    Patent number: 6372474
    Abstract: The present invention provides a cyclic lipopeptide acrylase which may effectively deacylate the acyl side chain of a cyclic lipopeptide compound, specifically FR901379 Substance or its analog thereof shown by the following general formula [I], and a process for production of a cyclic peptide compound which comprises the use of said acylase.
    Type: Grant
    Filed: September 12, 2000
    Date of Patent: April 16, 2002
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Satoshi Ueda, Miho Tanaka, Masami Ezaki, Kazutoshi Sakamoto, Seiji Hashimoto, Nobutaka Oohata, Masaru Tsuboi, Michio Yamashita
  • Process for the deacylation of cyclic lipopeptides
    Patent number: 6207434
    Abstract: There is provided a cyclic lipopeptide acylase which is capable of deacylating the acyl side chain of a cyclic lipopeptide compound, e.g. Substance FR901379 or its analog, of the general formula [I] with effectiveness as well a method of producing a cyclic peptide compound which comprises using the acylase.
    Type: Grant
    Filed: September 3, 1998
    Date of Patent: March 27, 2001
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Satoshi Ueda, Miho Tanaka, Masami Ezaki, Kazutoshi Sakamoto, Seiji Hashimoto, Nobutaka Oohata, Masaru Tsuboi, Michio Yamashita
  • Cyclic lipopeptide acylase
    Patent number: 6146872
    Abstract: The present invention provides a cyclic lipopeptide acylase which may effectively deacylate the acyl side chain of a cyclic lipopeptide compound, specifically FR901379 Substance or its analog thereof shown by the following general formula [I], and a process for production of a cyclic peptide compound which comprises the use of said acylase.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: November 14, 2000
    Assignee: Fukisawa Pharmaceutical Co., Ltd.
    Inventors: Satoshi Ueda, Miho Tanaka, Masami Ezaki, Kazutoshi Sakamoto, Seiji Hashimoto, Nobutaka Oohata, Masaru Tsuboi, Michio Yamashita
  • Anthraquinone derivatives and preparation thereof
    Patent number: 5187195
    Abstract: Anthraquinone compounds of the formula: ##STR1## wherein: R.sup.1 is hydrogen, hydroxy or acyloxy,R.sup.2 is hydrogen or acyl,R.sup.3 is acyl,R.sup.4 is hydrogen or acyl,R.sup.5 is hydrogen or acyl,R.sup.6 is hydrogen or acyl, andR.sup.7 is hydrogen or acylhave been found to possess endothelin antagonistic properties and are producible by various synthetic and fermentation processes.
    Type: Grant
    Filed: June 26, 1990
    Date of Patent: February 16, 1993
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Nobutaka Oohata, Motoaki Nishikawa, Sumio Kiyoto, Shigehiro Takase, Keiji Hemmi, Hidetsugu Murai, Masakuni Okuhara