Patents by Inventor Nobutoshi Ojima

Nobutoshi Ojima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic agents
    Patent number: 5292750
    Abstract: Compounds are described which are useful for lowering the activity of .alpha..sub.2 -PI, for the treatment of myocardial infarctions and cerebral infarctions, as urokinase secretion accelerators, as antithrombotic agents and to accelerate the fibrinolysis accelerating effect.
    Type: Grant
    Filed: September 8, 1992
    Date of Patent: March 8, 1994
    Assignee: Nippon Shinyaku Co. Ltd.
    Inventors: Yoshiaki Yoshikuni, Nobutoshi Ojima, Kazuya Mori
  • Therapeutic agents
    Patent number: 5192772
    Abstract: Compounds are described which are useful for lowering the activity of .alpha..sub.2 -PI, for the treatment of myocardial infarctions and cerebral infarctions, as urokinase secretion accelerators, as antithrombotic agents and to accelerate the fibrinolysis accelerating effect.
    Type: Grant
    Filed: August 12, 1991
    Date of Patent: March 9, 1993
    Assignee: Nippon Shinyaku Co. Ltd.
    Inventors: Yoshiaki Yoshikuni, Nobutoshi Ojima, Kazuya Mori
  • Method for manufacturing 2-amino-2-deoxy-D-mannitol
    Patent number: 4894344
    Abstract: 2-amino-2-deoxy-D-mannitol is produced from a microorganism strain of the genus Streptomyces or a mutant strain thereof in improved yields and purity.
    Type: Grant
    Filed: November 28, 1988
    Date of Patent: January 16, 1990
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Makoto Sugiyama, Yoji Ezure, Nobutoshi Ojima, Kiyotaka Konno, Takashi Seto, Teruya Nakamura, Manabu Itoh
  • Glucosylmoranoline derivatives and use thereof for inhibiting increase in blood sugar levels
    Patent number: 4859767
    Abstract: Compounds of formula I are useful in the prophylaxis or treatment of hyperglycemic symptoms ##STR1## wherein R is alkyl substituted by one or more hydroxy.
    Type: Grant
    Filed: October 10, 1986
    Date of Patent: August 22, 1989
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Makoto Sugiyama, Yoji Ezure, Yoshiaki Yoshikuni, Takayuki Ozaki, Nobutoshi Ojima
  • Physiologically active substances named SEN-366
    Patent number: 4751217
    Abstract: A compound of the formula (I): ##STR1## in which: is a single bond or a double bond,X is hydrogen or hydroxy,n is 0 or 1,Z is ##STR2## when in ring B is a double bond, and, when in ring B is a single bond, Z is wherein W is hydrogen, lower acyl, unsubstituted arylcarbonyl, lower alkyl or substituted arylcarbonyl.These compounds are useful as platelet aggregation inhibitors.
    Type: Grant
    Filed: October 22, 1985
    Date of Patent: June 14, 1988
    Assignees: Nippon Shinyaku Co., Ltd., Takara Shuzo Co., Ltd.
    Inventors: Masanobu Kawamata, Yoji Ezure, Nobutoshi Ojima, Kiyotaka Konno, Teruya Nakamura, Hideyuki Yasuda
  • Moranoline derivatives
    Patent number: 4363802
    Abstract: Bisglucosyl moranoline of the formula (I) ##STR1## is useful in inhibiting increase of blood sugar in sugar-loaded animals and humans, and particularly for treatment of diabetes mellitus.
    Type: Grant
    Filed: November 30, 1981
    Date of Patent: December 14, 1982
    Assignee: Nippon Shinyaku Co. Ltd.
    Inventors: Shingo Matsumura, deceased, Hiroshi Enomoto, Yoshiaki Aoyagi, Yoji Ezure, Yoshiaki Yoshikuni, Shigeaki Maruo, Nobutoshi Ojima, Kiyotaka Konno
  • Moranoline derivatives and process for preparation thereof
    Patent number: 4338433
    Abstract: Moranolines are produced which are useful for controlling blood sugar levels.
    Type: Grant
    Filed: December 8, 1980
    Date of Patent: July 6, 1982
    Assignee: Nippon Shinyaku Co. Ltd.
    Inventors: Shingo Matsumura, Hiroshi Enomoto, Yoshiaki Aoyagi, Yoji Ezure, Yoshiaki Yoshikuni, Masahiro Yagi, Nobutoshi Ojima