Patents by Inventor Nobuya Kitaguchi
Nobuya Kitaguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10112000Abstract: The present invention relates to a method for reducing a ?-amyloid concentration in blood. Specifically, the present invention relates to a method for reducing a ?-amyloid concentration in blood, comprising the steps of; removing blood out of a body, passing the blood that is removed through a hollow fiber membrane, and returning the blood that is passed through into the body, wherein the blood containing a ?-amyloid-albumin complex is passed through the hollow fiber membrane to allow ?-amyloid to adsorb to the hollow fiber membrane so that the ?-amyloid concentration in blood is reduced.Type: GrantFiled: July 8, 2011Date of Patent: October 30, 2018Assignees: ASAHI KASEI MEDICAL CO., LTD., SCHOOL JURIDICAL PERSON FUJITA EDUCATIONAL INSTITUTIONInventors: Nobuya Kitaguchi, Kazunori Kawaguchi
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Patent number: 9061108Abstract: An object is to provide a material capable of removing A? from a body fluid efficiently and use of the material, which are developed for the purpose of establishing a therapeutic or preventive method for Alzheimer's disease. Provided is an amyloid ? protein remover, containing a carrier made of any one material selected from the group consisting of cellulose, silica, polyvinyl alcohol, and activated carbon, wherein the carrier does not have an alkyl chain on the surface thereof or has an alkyl chain having 1 to 18 carbon atoms on the surface thereof.Type: GrantFiled: October 22, 2013Date of Patent: June 23, 2015Assignees: FUJITA HEALTH UNIVERSITY, KANEKA CORPORATIONInventors: Nobuya Kitaguchi, Kazunori Kawaguchi
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Publication number: 20140335149Abstract: The object of the present invention is to provide a means for utilizing cells that have effects on wound healing as wound-healing promoting materials by efficiently concentrating such cells within a short period of time. The present invention provides a wound-healing promoting material which comprises a sheet-like porous body having on its surface at least leukocytes and/or platelets, a method for producing the same, a device for producing the same, and a method for treating wound sites using the same.Type: ApplicationFiled: July 29, 2014Publication date: November 13, 2014Inventors: Ushio IWAMOTO, Yasuo TOKUSHIMA, Nobuya KITAGUCHI
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Publication number: 20140042098Abstract: An object is to provide a material capable of removing A? from a body fluid efficiently and use of the material, which are developed for the purpose of establishing a therapeutic or preventive method for Alzheimer's disease. Provided is an amyloid ? protein remover, containing a carrier made of any one material selected from the group consisting of cellulose, silica, polyvinyl alcohol, and activated carbon, wherein the carrier does not have an alkyl chain on the surface thereof or has an alkyl chain having 1 to 18 carbon atoms on the surface thereof.Type: ApplicationFiled: October 22, 2013Publication date: February 13, 2014Applicants: KANEKA CORPORATION, FUJITA HEALTH UNIVERSITYInventors: Nobuya Kitaguchi, Kazunori Kawaguchi
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Publication number: 20120031840Abstract: The present invention relates to a method for reducing a ?-amyloid concentration in blood. Specifically, the present invention relates to a method for reducing a ?-amyloid concentration in blood, comprising the steps of; removing blood out of a body, passing the blood that is removed through a hollow fiber membrane, and returning the blood that is passed through into the body, wherein the blood containing a ?-amyloid-albumin complex is passed through the hollow fiber membrane to allow ?-amyloid to adsorb to the hollow fiber membrane so that the ?-amyloid concentration in blood is reduced.Type: ApplicationFiled: July 8, 2011Publication date: February 9, 2012Applicants: SCHOOL JURIDICAL PERSON FUJITA EDUCATIONAL INSTITUTION, ASAHI KASEI KURARAY MEDICAL CO., LTD.Inventors: Nobuya KITAGUCHI, Kazunori KAWAGUCHI
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Publication number: 20110274594Abstract: An object is to provide a material capable of removing A? from a body fluid efficiently and use of the material, which are developed for the purpose of establishing a therapeutic or preventive method for Alzheimer's disease. Provided is an amyloid ? protein remover, containing a carrier made of any one material selected from the group consisting of cellulose, silica, polyvinyl alcohol, and activated carbon, wherein the carrier does not have an alkyl chain on the surface thereof or has an alkyl chain having 1 to 18 carbon atoms on the surface thereof.Type: ApplicationFiled: June 22, 2011Publication date: November 10, 2011Applicants: KANEKA CORPORATION, FUJITA HEALTH UNIVERSITYInventors: Nobuya Kitaguchi, Kazunori Kawaguchi
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Patent number: 7625760Abstract: An analyzing cartridge and method for using it to analyze a sample having a plurality of reservoirs and capillaries connected for communication between these reservoirs and is provided therein with a reagent required for analysis. The reservoirs are provided with openings leading to the outside of the cartridge, and the openings are covered with vents each consisting of a gas-permeable/non-liquid-permeable, hydrophobic, porous membrane. The analyzing cartridge requires only trace amounts of a sample and a reagent and no maintenance. It is provided with a non-fluid reagent in vent-carrying reservoirs thereby making it possible to formulate a very trace amount of reagent solution in the cartridge by injecting a reagent dissolving liquid into the reservoirs immediately before analyzing. A liquid feed control device controls the feeding of the liquid between the reservoirs via the capillaries when it is attached to the cartridge to allow or control the entry/exit of air via the vents.Type: GrantFiled: February 14, 2005Date of Patent: December 1, 2009Assignee: Asahi Kasei Kabushiki KaishaInventors: Nobuya Kitaguchi, Akira Kiguchi
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Publication number: 20060257456Abstract: The object of the present invention is to provide a means for utilizing cells that have effects on wound healing as wound-healing promoting materials by efficiently concentrating such cells within a short period of time. The present invention provides a wound-healing promoting material which comprises a sheet-like porous body having on its surface at least leukocytes and/or platelets, a method for producing the same, a device for producing the same, and a method for treating wound sites using the same.Type: ApplicationFiled: June 7, 2004Publication date: November 16, 2006Applicant: Asahi Kasei Medical Co., Ltd.Inventors: Ushio Iwamoto, Yasuo Tokushima, Nobuya Kitaguchi
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Publication number: 20060128016Abstract: It is intended to provide a scaffold material having favorable properties and being appropriate for cell proliferation and differentiation in regeneration therapy. Namely, a fibrin-containing biological scaffold material to be used in the case of employing a fibrin composition for the regeneration of a human tissue and cell proliferation, characterized by containing a mixture of a fibrinogen concentrate, which is obtained from human plasma by a quick and rough purification method, with a fibrinogen activator.Type: ApplicationFiled: August 25, 2003Publication date: June 15, 2006Inventors: Yasuo Tokushima, Nobuya Kitaguchi, Shuichiro Inadome, Takahiro Hori
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Publication number: 20050148091Abstract: An analyzing cartridge and method for using it to analyze a sample having a plurality of reservoirs and capillaries connected for communication between these reservoirs and is provided therein with a reagent required for analysis. The reservoirs are provided with openings leading to the outside of the cartridge, and the openings are covered with vents each consisting of a gas-permeable/non-liquid-permeable, hydrophobic, porous membrane. The analyzing cartridge requires only trace amounts of a sample and a reagent and no maintenance. It is provided with a non-fluid reagent in vent-carrying reservoirs thereby making it possible to formulate a very trace amount of reagent solution in the cartridge by injecting a reagent dissolving liquid into the reservoirs immediately before analyzing. A liquid feed control device controls the feeding of the liquid between the reservoirs via the capillaries when it is attached to the cartridge to allow or control the entry/exit of air via the vents.Type: ApplicationFiled: February 14, 2005Publication date: July 7, 2005Inventors: Nobuya Kitaguchi, Akira Kiguchi
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Patent number: 6458347Abstract: Disclosed is a drug complex of a drug having a hydroxyl group, which is capable of controlling the rate of the release of the drug therefrom in blood, the drug complex being represented by the following formula (1): A—B—C (1) wherein A represents at least one carrier selected from the group consisting of saccharides each having a carboxyl group, polyethylene glycols each having a carboxyl group, aliphatic carboxylic acids each having a carboxyl group, and derivatives thereof each having a carboxyl group; B represents at least one spacer comprised of a compound having a amino group and a carboxyl group; C represents at least one drug having a hydroxyl group, wherein the carrier A is bonded to the spacer B through an amide bond formed between the carboxyl group of the carrier A and the amino group of the spacer B; and the spacer B is bonded to the drug C through an ester bond formed between the carboxyl group of the spacer B and the hydroxyl group of the drug C.Type: GrantFiled: October 14, 1998Date of Patent: October 1, 2002Assignee: Asahi Kasei Kabushiki KaishaInventors: Shuichi Sugawara, Masahiro Kajiki, Hiroshi Kuriyama, Nobuya Kitaguchi
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Patent number: 4414079Abstract: The electrolytic reduction of a mixture of an acrylic ester and an aldehyde in the form of an aqueous emulsion in the presence of at least one phase-transfer catalyst using a lead or lead alloy cathode has been found to be very effective for preparing a 4-butanolide compound simply and safely in high yield with a high current efficiency.Type: GrantFiled: July 15, 1982Date of Patent: November 8, 1983Assignee: Asahi Kasei Kogyo Kabushiki KaishaInventors: Kazunori Yamataka, Toshiro Isoya, Nobuya Kitaguchi