Patents by Inventor Noona Ambartsumian

Noona Ambartsumian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-S100A4 antibody molecules and their uses
    Patent number: 9683032
    Abstract: Anti-S100A4 antibody molecules that are capable of inhibiting the biological activity of S100A4 in promoting tumor progression and/or in inducing tumor metastasis are described. The antibody molecules are also useful in the treatment of inflammatory conditions. The properties of the antibodies are demonstrated using in vitro and in vivo assays.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: June 20, 2017
    Assignee: Cancer Research Technology Limited
    Inventors: Jorg Klingelhöfer, Noona Ambartsumian, Mariam Grigorian, Eugene Lukanidin
  • ANTI-S100A4 ANTIBODY MOLECULES AND THEIR USES
    Publication number: 20160159888
    Abstract: Anti-S100A4 antibody molecules that are capable of inhibiting the biological activity of S100A4 in promoting tumour progression and/or in inducing tumour metastasis are described. The antibody molecules are also useful in the treatment of inflammatory conditions. The properties of the antibodies are demonstrated using in vitro and in vivo assays.
    Type: Application
    Filed: October 29, 2013
    Publication date: June 9, 2016
    Inventors: Jorg Klingelhöfer, Noona Ambartsumian, Mariam Grigorian, Eugene Lukanidin
  • Therapeutic compositions and methods for enhancing angiogenesis
    Publication number: 20030004110
    Abstract: The present inventors have surprisingly found that the Mts-1 protein stimulates angiogenesis. In particular, the present inventors have found that Mts-1 transgenic mice developed hemangiomas and stenosis. The present inventors have also found that addition of Mts-1 proteins to the culture media increases the motility of mouse endothelial cells. Further, the present inventors have found that injection of Mts1 proteins stimulates angiogenesis in the mouse corneas. Accordingly, the present invention provides methods of enhancing angiogenesis in a subject in need thereof by administering a therapeutically effective amount of an angiogenic Mts-1 component.
    Type: Application
    Filed: August 13, 2002
    Publication date: January 2, 2003
    Inventors: Eugene M. Lukanidin, Noona Ambartsumian
  • Therapeutic compositions and methods for enhancing angiogenesis
    Patent number: 6468960
    Abstract: The present inventors have surprisingly found that the Mts-1 protein stimulates angiogenesis. In particular, the present inventors have found that Mts-1 transgenic mice developed hemangiomas and stenosis. The present inventors have also found that addition of Mts-1 proteins to the culture media increases the motility of mouse endothelial cells. Further, the present inventors have found that injection of Mts1 proteins stimulates angiogenesis in the mouse corneas. Accordingly, the present invention provides methods of enhancing angiogenesis in a subject in need thereof by administering a therapeutically effective amount of an angiogenic Mts-1 component.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: October 22, 2002
    Assignee: Prolifia, Inc.
    Inventors: Eugene M. Lukanidin, Noona Ambartsumian