Patents by Inventor Norihiko Hirata
Norihiko Hirata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10013678Abstract: A battery secondary use management system for managing a secondary use destination of a battery in use by using information of the battery includes an expired use time prediction unit configured to obtain estimated degradation information of the battery in use and predict an expired use time of the battery in use on the basis of the estimated degradation information which is acquired, and a secondary use destination determining unit configured to determine in advance the secondary use destination of the battery in use before expiration of use on the basis of the expiration-of-use date which is predicted.Type: GrantFiled: July 14, 2014Date of Patent: July 3, 2018Assignee: Nissan Motor Co., Ltd.Inventors: Chizuru Matsuyama, Norihiko Hirata
-
Patent number: 9970043Abstract: A process for producing an optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane (2), comprising a step of asymmetric hydrolysis of 2-alkyl-1,1,3-trialokoxycarbonylpropane (1) by using an enzyme capable of selectively hydrolyzing an ester moiety of either one enantiomer of 2-alkyl-1,1,3-trialkoxycarbonylpropane (1), or by using a culture of a microorganism capable of producing the enzyme or a treated object thereof.Type: GrantFiled: November 30, 2016Date of Patent: May 15, 2018Assignee: GENENTECH, INC.Inventors: Norihiko Hirata, Kazuhiro Yamauchi
-
Publication number: 20170145468Abstract: A process for producing an optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane (2), comprising a step of asymmetric hydrolysis of 2-alkyl-1,1,3-trialokoxycarbonylpropane (1) by using an enzyme capable of selectively hydrolyzing an ester moiety of either one enantiomer of 2-alkyl-1,1,3-trialkoxycarbonylpropane (1), or by using a culture of a microorganism capable of producing the enzyme or a treated object thereof.Type: ApplicationFiled: November 30, 2016Publication date: May 25, 2017Applicant: GENENTECH, INC.Inventors: Norihiko HIRATA, Kazuhiro YAMAUCHI
-
Publication number: 20160162849Abstract: A battery secondary use management system for managing a secondary use destination of a battery in use by using information of the battery includes an expired use time prediction unit configured to obtain estimated degradation information of the battery in use and predict an expired use time of the battery in use on the basis of the estimated degradation information which is acquired, and a secondary use destination determining unit configured to determine in advance the secondary use destination of the battery in use before expiration of use on the basis of the expiration-of-use date which is predicted.Type: ApplicationFiled: July 14, 2014Publication date: June 9, 2016Inventors: Chizuru MATSUYAMA, Norihiko HIRATA
-
Publication number: 20150218602Abstract: A process for producing an optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane (2), comprising a step of asymmetric hydrolysis of 2-alkyl-1,1,3-trialokoxycarbonylpropane (1) by using an enzyme capable of selectively hydrolyzing an ester moiety of either one enantiomer of 2-alkyl-1,1,3-trialkoxycarbonylpropane (1), or by using a culture of a microorganism capable of producing the enzyme or a treated object thereof.Type: ApplicationFiled: February 10, 2015Publication date: August 6, 2015Inventors: Norihiko HIRATA, Kazuhiro YAMAUCHI
-
Patent number: 8969051Abstract: A process for producing an optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane (2), comprising a step of asymmetric hydrolysis of 2-alkyl-1,1,3-trialokoxycarbonylpropane (1) by using an enzyme capable of selectively hydrolyzing an ester moiety of either one enantiomer of 2-alkyl-1,1,3-trialkoxycarbonylpropane (1), or by using a culture of a microorganism capable of producing the enzyme or a treated object thereof.Type: GrantFiled: May 9, 2008Date of Patent: March 3, 2015Assignee: Sumitomo Chemical Company, LimitedInventors: Norihiko Hirata, Kazuhiro Yamauchi
-
Patent number: 8822724Abstract: A carboxamide can be produced in a high yield by a method for producing a carboxamide, for example, represented by formula (4): (wherein R1 and R3 are as defined below), the method comprising a step of allowing a carboxylic acid ester represented by formula (1): (wherein R1 represents an optionally substituented C1-C20 hydrocarbon group or an optionally substituented C3-C20 heterocyclic group, and R2 represents an optionally substituented C1-C20 hydrocarbon group), an amine represented by formula (2): R3—NH2??(2) (wherein R3 represents a hydrogen atom or an optionally substituented C1-C20 hydrocarbon group), and a formamide compound represented by formula (3): (wherein R3 is as defined above) to react in the presence of a metal alkoxide.Type: GrantFiled: July 13, 2011Date of Patent: September 2, 2014Assignee: Sumitomo Chemical Company, LimitedInventors: Junichi Tomokawa, Takahiro Kimura, Norihiko Hirata
-
Patent number: 8691548Abstract: The present invention relates to, for example, an ?-substituted ?-amino acid ester derivative asymmetric hydrolase including an enzyme of the following (a) or (b): (a) an enzyme comprising the amino acid sequence of SEQ ID NO:1 at least from position 1 to position 362, wherein the tyrosine at position 277 of SEQ ID NO:1 is substituted with alanine, tryptophan, isoleucine, or histidine, and having the ability to hydrolyze a substrate; or (b) an enzyme comprising the amino acid sequence of SEQ ID NO:1 at least from position 1 to position 362, wherein the tyrosine at position 277 of SEQ ID NO:1 is substituted with an amino acid other than tyrosine, and having the ability to hydrolyze a substrate.Type: GrantFiled: December 18, 2012Date of Patent: April 8, 2014Assignee: Sumitomo Chemical Company, LimitedInventors: Toshihiko Akiyama, Norihiko Hirata, Shinji Hourai
-
Publication number: 20130123505Abstract: A carboxamide can be produced in a high yield by a method for producing a carboxamide, for example, represented by formula (4): (wherein R1 and R3 are as defined below), the method comprising a step of allowing a carboxylic acid ester represented by formula (1): (wherein R1 represents an optionally substituented C1-C20 hydrocarbon group or an optionally substituented C3-C20 heterocyclic group, and R2 represents an optionally substituented C1-C20 hydrocarbon group), an amine represented by formula (2): R3—NH2 ??(2) (wherein R3 represents a hydrogen atom or an optionally substituented C1-C20 hydrocarbon group), and a formamide compound represented by formula (3): (wherein R3 is as defined above) to react in the presence of a metal alkoxide.Type: ApplicationFiled: July 13, 2011Publication date: May 16, 2013Inventors: Junichi Tomokawa, Takahiro Kimura, Norihiko Hirata
-
Patent number: 8409831Abstract: The present invention provides a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid with a high yield and high selectivity. Specifically, disclosed is a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid, wherein (1S)-2-chloro-2-fluorocyclopropanecarboxylic acid ester is hydrolyzed using an esterase derived from Burkholderia cepacia.Type: GrantFiled: July 7, 2009Date of Patent: April 2, 2013Assignees: Sumitomo Chemical Company, Limited, Daiichi Sankyo Company, LimitedInventors: Keisuke Hatakeyama, Takashi Miki, Norihiko Hirata
-
Patent number: 8242285Abstract: N-tert-butoxycarbonyl-2-pyrrolidinones represented by the following formula (1). In the formula (1), R1, R2, R3, R4, R5 and R6 independently represent a hydrogen atom, a halogen atom, a cyano group, a linear, branched or cyclic alkyl group having 1 to 10 carbon atoms, which may have a substituent, a linear, branched or cyclic alkenyl group having 2 to 10 carbon atoms, which may have a substituent, or the like, R1 and R2 may be linked to form a >C?O group along with the carbon atom to which both are attached, R3 and R4 may be linked to form a >C?O group along with the carbon atom to which both are attached, R5 and R6 may be linked to form a >C?O group along with the carbon atom to which both are attached, or any two among R1, R2, R3, R4, R5 and R6 may be linked to form a polymethylene group having 1 to 4 carbon atoms which may have a substituent.Type: GrantFiled: July 19, 2010Date of Patent: August 14, 2012Assignee: Sumitomo Chemical Company, LimitedInventors: Norihiko Hirata, Toshitsugi Uemura
-
Patent number: 8153830Abstract: A method of producing an asymmetric copper complex crystal comprising reacting an optically active salicylidene amino alcohol compound with a copper compound, then, performing a crystallization treatment in the presence of an alcohol solvent.Type: GrantFiled: October 11, 2007Date of Patent: April 10, 2012Assignee: Sumitomo Chemical Company, LimitedInventors: Norihiko Hirata, Takanori Yoshimiya, Yoshihiko Iwanaga
-
Patent number: 8138370Abstract: A method is provided for producing optically active ?-amino acid benzyl esters. The method includes reacting an optically active ?-amino acid and benzyl alcohols in the presence of an acid, wherein the reaction is carried out under reduced pressure without substantially using a solvent, while distilling off water generated by the progress of the reaction.Type: GrantFiled: August 20, 2007Date of Patent: March 20, 2012Assignee: Sumitomo Chemical Company, LimitedInventor: Norihiko Hirata
-
Publication number: 20110117616Abstract: The present invention provides a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid with a high yield and high selectivity. Specifically, disclosed is a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid, wherein (1S)-2-chloro-2-fluorocyclopropanecarboxylic acid ester is hydrolyzed using an esterase derived from Burkholderia cepacia.Type: ApplicationFiled: July 7, 2009Publication date: May 19, 2011Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Keisuke Hatakeyama, Takashi Miki, Norihiko Hirata
-
Patent number: 7928253Abstract: A method of producing 6,6-dimethyl-3 -oxabicyclo [3.1.0]hexan-2-one comprising subjecting a cyclopropane compound of the formula (1): (wherein, R1 represents an alkyl group, R2 represents an alkyl group having carbon atom(s) of 1 to 10, a haloalkyl group having carbon atom(s) of 1 to 10, or an aryl group having carbon atoms of 6 to 10 optionally substituted by an alkyl group having carbon atom(s) of 1 to 10, and when R2 represents the alkyl group, R1 and R2 are optionally the same or different each other.) to any of the following reactions a), b) and c): a) an acid treatment reaction after an alkali hydrolysis reaction b) an acid hydrolysis reaction c) an enzyme hydrolysis reaction , then, removing an aqueous layer.Type: GrantFiled: June 28, 2006Date of Patent: April 19, 2011Assignee: Sumitomo Chemical Company, LimitedInventors: Norihiko Hirata, Toshitsugi Uemura
-
Publication number: 20100324305Abstract: A process for producing lactams of formula (1) below, including the step of reacting lactones of formula (2) below with imides of any of formulae (3a), (3b) and (3c) below to thereby obtain corresponding carboxylic acids (step A); the step of esterifying the carboxylic acids into corresponding esters (step B); and the step of reacting the esters with amines to thereby obtain lactams of the formula (1) (step C). In the formulae (1)-(2) and (3a)-(3c), when R3 and R4 are simultaneously hydrogen atoms, R is a substituted methylene or optionally substituted polymethylene; when at least one of R3 and R4 is a substituent other than hydrogen atom, R is an optionally substituted methylene or polymethylene; each of R3, R4, R5 and R6 independently is a hydrogen atom, a halogen atom, cyano, etc.; each of A1, A2, A3, A4, A5, A6, A7, A8, A9 and A10 independently is a hydrogen atom, a halogen atom, nitro, etc.; and M is a hydrogen atom or an alkali metal atom.Type: ApplicationFiled: September 1, 2010Publication date: December 23, 2010Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Norihiko HIRATA, Toshitsugi UEMURA, Hideki USHIO
-
Publication number: 20100280259Abstract: N-tert-butoxycarbonyl-2-pyrrolidinones represented by the following formula (1). In the formula (1), R1, R2, R3, R4, R5 and R6 independently represent a hydrogen atom, a halogen atom, a cyano group, a linear, branched or cyclic alkyl group having 1 to 10 carbon atoms, which may have a substituent, a linear, branched or cyclic alkenyl group having 2 to 10 carbon atoms, which may have a substituent, or the like, R1 and R2 may be linked to form a >C?O group along with the carbon atom to which both are attached, R3 and R4 may be linked to form a >C?O group along with the carbon atom to which both are attached, R5 and R6 may be linked to form a >C?O group along with the carbon atom to which both are attached, or any two among R1, R2, R3, R4, R5 and R6 may be linked to form a polymethylene group having 1 to 4 carbon atoms which may have a substituent.Type: ApplicationFiled: July 19, 2010Publication date: November 4, 2010Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Norihiko Hirata, Toshitsugi Uemura
-
Publication number: 20100240107Abstract: A process for producing an optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane (2), comprising a step of asymmetric hydrolysis of 2-alkyl-1,1,3-trialokoxycarbonylpropane (1) by using an enzyme capable of selectively hydrolyzing an ester moiety of either one enantiomer of 2-alkyl-1,1,3-trialkoxycarbonylpropane (1), or by using a culture of a microorganism capable of producing the enzyme or a treated object thereof.Type: ApplicationFiled: May 9, 2009Publication date: September 23, 2010Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Norihiko Hirata, Kazuhiro Yamauchi
-
Publication number: 20100168463Abstract: A method of producing 6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one comprising subjecting a cyclopropane compound of the formula (1): (wherein, R1 represents an alkyl group, R2 represents an alkyl group having carbon atom(s) of 1 to 10, a haloalkyl group having carbon atom(s) of 1 to 10, or an aryl group having carbon atoms of 6 to 10 optionally substituted by an alkyl group having carbon atom(s) of 1 to 10, and when R2 represents the alkyl group, R1 and R2 are optionally the same or different each other.) to any of the following reactions a), b) and c): a) an acid treatment reaction after an alkali hydrolysis reaction b) an acid hydrolysis reaction c) an enzyme hydrolysis reaction , then, removing an aqueous layer.Type: ApplicationFiled: June 28, 2006Publication date: July 1, 2010Inventors: Norihiko Hirata, Toshitsugi Uemura
-
Publication number: 20100094036Abstract: A method of producing an asymmetric copper complex crystal comprising reacting an optically active salicylidene amino alcohol compound with a copper compound, then, performing a crystallization treatment in the presence of an alcohol solvent.Type: ApplicationFiled: October 11, 2007Publication date: April 15, 2010Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Norihiko Hirata, Takanori Yoshimiya, Yoshihiko Iwanaga