Patents by Inventor Norihiro Sato
Norihiro Sato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8785614Abstract: The present invention provides a method for detecting pancreatic carcinoma in a subject. The method includes contacting a nucleic acid-containing specimen from the subject with an agent that provides a determination of the methylation state of at least one gene or associated regulatory region of the gene and identifying aberrant methylation of regions of the gene or regulatory region, wherein aberrant methylation is identified as being different when compared to the same regions of the gene or associated regulatory region in a subject not having the pancreatic carcinoma, thereby detecting pancreatic carcinoma in the subject.Type: GrantFiled: January 9, 2009Date of Patent: July 22, 2014Assignee: The Johns Hopkins UniversityInventors: Michael G. Goggins, Norihiro Sato
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Publication number: 20110003284Abstract: The present invention provides a method for detecting pancreatic carcinoma in a subject. The method includes contacting a nucleic acid-containing specimen from the subject with an agent that provides a determination of the methylation state of at least one gene or associated regulatory region of the gene and identifying aberrant methylation of regions of the gene or regulatory region, wherein aberrant methylation is identified as being different when compared to the same regions of the gene or associated regulatory region in a subject not having the pancreatic carcinoma, thereby detecting pancreatic carcinoma in the subject.Type: ApplicationFiled: January 9, 2009Publication date: January 6, 2011Inventors: Michael G. Goggins, Norihiro Sato
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Patent number: 7485418Abstract: The present invention provides a method for detecting pancreatic carcinoma in a subject. The method includes contacting a nucleic acid-containing specimen from the subject with an agent that provides a determination of the methylation state of at least one gene or associated regulatory region of the gene and identifying aberrant methylation of regions of the gene or regulatory region, wherein aberrant methylation is identified as being different when compared to the same regions of the gene or associated regulatory region in a subject not having the pancreatic carcinoma, thereby detecting pancreatic carcinoma in the subject.Type: GrantFiled: March 17, 2004Date of Patent: February 3, 2009Assignee: The Johns Hopkins UniversityInventors: Michael G. Goggins, Norihiro Sato
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Patent number: 5997775Abstract: The electrically conductive, barium sulfate-containing composition consists of BaSO.sub.4 particles having a surface area of from 0.1 to 150 m.sup.2 /g. The BaSO.sub.4 particles each are provided with a SnO.sub.2 coating having a thickness of 2 to 80 nm and containing from 1 to 15% by weight of the Sb.sub.2 O.sub.3. The electrically conductive, barium sulfate-containing composition is made by a method including the steps of adding a first acidic solution containing 1 to 95% by weight SnCl.sub.4 and a basic solution to an aqueous dispersion from 50 to 800 g/l of BaSO.sub.4 to make a basic mixture having a pH from 9 to 15; then adding an acid to the basic mixture to form an acidic mixture having a pH from 4 to 1; then adding a second acid solution containing 0.5 to 60% by weight of SbCl.sub.Type: GrantFiled: November 21, 1997Date of Patent: December 7, 1999Assignee: Mitsui Kinzoku Mitsui Maining & Smelting Co. Ltd.Inventors: Takao Hayashi, Norihiro Sato, Manabu Hosoi, Nobuyoshi Kasahara, Clemens Aderhold, Wolf-Dieter Griebler, Jorg Hocken, Uwe Rosin, Gunther Rudolph
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Patent number: 5919518Abstract: A electrically-conductive barium sulfate filler and a method for preparing same are herein disclosed and it comprises a particulate core material composed of barium sulfate provided thereon with a coating film of tin dioxide which may be optionally doped with niobium or tentalum, the bare core material free of coating film having a specific surface area ranging from 0.1 to 150 m.sup.2 /g and the film having a thickness ranging from 2 to 80 nm.Type: GrantFiled: July 31, 1997Date of Patent: July 6, 1999Assignee: Mitsui Mining & Smelting Co., Ltd.Inventors: Takao Hayashi, Norihiro Sato, Nobuyoshi Kasahara, Katsuhiko Yoshimaru, Kouichi Kawaratani
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Patent number: 5698315Abstract: A electrically-conductive barium sulfate filler and a method for preparing same are herein disclosed and it comprises a particulate core material composed of barium sulfate provided thereon with a coating film of tin dioxide which may be optionally doped with niobium or tentalum, the bare core material free of coating film having a specific surface area ranging from 0.1 to 150 m.sup.2 /g and the film having a thickness ranging from 2 to 80 nm.Type: GrantFiled: May 23, 1996Date of Patent: December 16, 1997Assignee: Mitsui Mining & Smelting Co., Ltd.Inventors: Takao Hayashi, Norihiro Sato, Nobuyoshi Kasahara, Katsuhiko Yoshimaru, Kouichi Kawaratani
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Patent number: 5612087Abstract: A fibrous electrically-conductive filler herein provided comprises fibrous aluminum borate as a core material provided thereon with, in order, an optional titanium oxide intermediate layer and an antimony-free tin oxide layer. The fibrous electrically-conductive filler can be prepared by a method which comprises the steps of optionally forming an intermediate layer of titanium oxide by depositing titanium oxide hydrate on the surface of the core material and then calcining the titanium oxide hydrate layer; then forming a coating layer of tin oxide hydrate on the surface of the titanium oxide-coated fibrous aluminum borate or the fibrous aluminum borate as a core material and then calcining the coating layer at a temperature ranging from 150.degree. to 600.degree. C. in an inert gas atmosphere or a reducing atmosphere to form an antimony-free tin oxide layer.Type: GrantFiled: November 30, 1995Date of Patent: March 18, 1997Assignee: Mitsui Mining & Smelting Co., Ltd.Inventors: Takao Hayashi, Nobuyoshi Kasahara, Norihiro Sato, Kouichi Kawaratani
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Patent number: 5501907Abstract: A fibrous electrically-conductive filler herein provided comprises fibrous aluminum borate as a core material provided thereon with, in order, an optional titanium oxide intermediate layer and an antimony-free tin oxide layer. The fibrous electrically-conductive filler can be prepared by a method which comprises the steps of optionally forming an intermediate layer of titanium oxide by depositing titanium oxide hydrate on the surface of the core material and then calcining the titanium oxide hydrate layer; then forming a coating layer of tin oxide hydrate on the surface of the titanium oxide-coated fibrous aluminum borate or the fibrous aluminum borate as a core material and then calcining the coating layer at a temperature ranging from 150.degree. to 600.degree. C. in an inert gas atmosphere or a reducing atmosphere to form an antimony-free tin oxide layer.Type: GrantFiled: September 29, 1993Date of Patent: March 26, 1996Assignee: Mitsui Mining & Smelting Co., Ltd.Inventors: Takao Hayashi, Nobuyoshi Kasahara, Norihiro Sato, Kouichi Kawaratani
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Patent number: 5424055Abstract: The composite oxide comprises, by weight, 100 parts of zinc oxide and at least one member, incorporated therein, selected from seven specific oxides in their specific amounts such as 0.001 to 5.0 parts of lanthanum oxide, 1.0 to 10.0 parts of cobalt oxide, 1.0 to 30.0 parts of titanium oxide, the composite oxide being surface treated with a silicone oil or a fatty acid to provide a surface-treated composite oxide of the present invention which has excellent ultraviolet screening capability and high visible light transmittance, these superior properties being well balanced with each other, and can maintain said superior properties over a long period of time. In one embodiment, there is provided a process for producing the ultraviolet screening surface-treated composite oxide.Type: GrantFiled: March 22, 1993Date of Patent: June 13, 1995Assignee: Mitsui Mining & Smelting Co., Ltd.Inventors: Takao Hayashi, Norihiro Sato, Hosoi, Manabu, Nobuyoshi Kasahara, Katsuhiko Yoshimaru
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Patent number: 5312614Abstract: A method is provided for the high yield production of white, electrically conductive zinc oxide which comprises the simultaneous addition to a reactor of (1) an aqueous solution containing a water-soluble zinc compound and at least one water-soluble compound of a metal selected from the group consisting of tin, aluminum, gallium and indium, and (2) an aqueous alkaline solution, while maintaining the resulting neutralization reaction solution at a pH from 6 to 12.5 to obtain coprecipitates, and then calcining the coprecipitates in a reducing atmosphere to obtain said conductive zinc oxide.Type: GrantFiled: June 14, 1990Date of Patent: May 17, 1994Assignee: Metallgesellschaft AktiengesellschaftInventors: Takao Hayashi, Norihiro Sato, Chikara Omotani, Manabu Hosoi, Nobuyoshi Kasahara, Gunther Rudolph, Wolf-Dieter Griebler, Jorg Hocken
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Patent number: 5273822Abstract: A fibrous electrically-conductive filler comprises fibrous aluminum borate as a core material and a layer of a electrically-conductive substance which covers the core material or comprises fibrous aluminum borate as a core material, a layer of titanium oxide which covers the fibrous aluminum borate and a layer of a electrically-conductive substance which covers the titanium oxide layer. The fibrous electrically-conductive filler can be prepared by a process comprising the step of directly forming a layer of a electrically-conductive substance doped with antimony or fluorine on the surface of fibrous aluminum borate, or the steps of forming, on the surface of the fibrous aluminum borate, an intermediate layer of titanium oxide in an amount ranging from 2 to 50% by weight on the basis of the weight of the fibrous aluminum borate and then forming a layer of a electrically-conductive substance doped with antimony or fluorine on the surface of fibrous aluminum borate.Type: GrantFiled: November 26, 1991Date of Patent: December 28, 1993Assignees: Mitsui Mining & Smelting Co., Ltd., Metallgesellschaft AktiengesellschaftInventors: Takao Hayashi, Norihiro Sato, Chikara Omotani, Manabu Hosoi, Nobuyoshi Kasahara, Wolf-Dieter Griebler, Jorg Hocken, Gunther Rudolph
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Patent number: 5171364Abstract: A process for preparing a conductive, acicular zinc oxide, comprising the steps of: preparing a zinc oxide slurry comprising an acicular zinc oxide, a salt of at least one metal selected from the group consisting of aluminum, gallium, indium and tin and an aqueous solution of an alkali metal hydroxide and having a pH value maintained at 10 to 13, adjusting the pH value of said zinc oxide slurry to 5 to 9 while stirring, aging the slurry, separating the zinc oxide present in the slurry by filtration, washing and drying the separated zinc oxide, and then firing the dried zinc oxide at 500.degree. to 700.degree. C. in a reducing atmosphere.Type: GrantFiled: November 13, 1991Date of Patent: December 15, 1992Assignees: Mitsui Mining & Smelting Co. Ltd., Metallgesellschaft AktiengesellschaftInventors: Norihiro Sato, Takao Hayashi, Nobuyoshi Kasahara, Wolf-Dieter Griebler, Jorg Hocken, Gunther Rudolph
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Patent number: 5131952Abstract: An electrically conductive powder is provided which comprises particles of zinc sulfide coated with an elecctrically conductive coating of copper sulfide wherein the zinc sulfide particles have a BET surface area of 2 to 10 m.sup.2 /g and a purity of at least 97%, and is particularly useful to impart antistatic properties to plastics, synthetic fibers, laminated papers and the like.Type: GrantFiled: August 10, 1990Date of Patent: July 21, 1992Assignees: Metallgesellschaft Aktiengesellschaft, Mitsui Mining & Smelting Co., Ltd.Inventors: Takao Hayashi, Norihiro Sato, Manabu Hosoi, Nobuyoshi Kasahara, Clemens Aderhold, Wolf-Dieter Griebler, Jorg Hocken, Uwe Rosin, Gunther Rudolph
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Patent number: 5102650Abstract: Needle-like electrically conductive zinc oxide filler having low specific volume resistance and excellent electrical conductivity-imparting effect per unit weight thereof is provided, including a method for its preparation.Type: GrantFiled: June 26, 1990Date of Patent: April 7, 1992Assignees: Metallgesellschaft Aktiengesellschaft, Mitsui Mining & Smelting Co., Ltd.Inventors: Takao Hayashi, Norihiro Sato, Chikara Omotani, Manabu Hosoi, Nobuyoshi Kasahara, Gunther Rudolph, Wolf-Dieter Griebler, Jorg Hocken