Patents by Inventor Norihiro Tada

Norihiro Tada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mouse expressing an .beta.-Amyloid transgene
    Patent number: 6037521
    Abstract: The invention relates to an animal model of human Alzheimer's disease that is useful for determining the mechanism of the disease and for developing and testing potential therapeutic drugs. More particularly, the present invention relates to the creation of transgenic non-human mammalian animals having integrated into their genome an exogenous DNA construct that encodes a portion of a .beta.-amyloid precursor protein ("APP") and that is designed to overexpress in various types of animal tissues.
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: March 14, 2000
    Assignee: Hoechst Japan Limited
    Inventors: Masahiro Sato, Takashi Kobayashi, Norihiro Tada, Mikio Shoji, Takeshi Kawarabayashi
  • Transgenic mice as a model for metabolic bone diseases
    Patent number: 5849993
    Abstract: Transgenic mice carrying a recombinant DNA construct comprising the gene encoding diphtheria toxin A chain operably linked to a osteocalcin promoter. The transgenic mice can be used as a model for metabolic bone diseases since they have decreased bone mass associated with a marked reduction in the number of osteoblasts.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: December 15, 1998
    Assignee: Hoechst Japan Limited
    Inventors: Norihiro Tada, Masahiro Sato, Takashi Kobayashi, Toru Ikeda, Katsuiku Hirokawa