Patents by Inventor Norman H. Grant

Norman H. Grant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitor of mammalian collagenase and elastase
    Patent number: 4609667
    Abstract: A method of inhibiting mammalian elastase and collagenase by using [benzothiazolylthio]phenylacetyl-L-cysteines and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: March 21, 1985
    Date of Patent: September 2, 1986
    Assignee: American Home Products Corporation
    Inventors: Donald E. Clark, Norman H. Grant
  • Vaccine adjuvants
    Patent number: 4466957
    Abstract: There are disclosed mammalian vaccine compositions comprising an inactivated whole or subunit vaccine or toxoid and an adjuvant having the formula ##STR1## wherein R is hydrogen or lower alkyl, R.sub.1 is hydrogen, lower alkyl, lower alkoxy, trifluoromethyl or halo, R.sub.2 is hydrogen, chloro or nitro, n is 1 or 2 and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: February 25, 1982
    Date of Patent: August 21, 1984
    Assignee: American Home Products Corporation
    Inventors: Richard N. Hjorth, Bobby O. Moore, Norman H. Grant
  • Inhibitors of mammalian collagenase
    Patent number: 4367233
    Abstract: A method of inhibiting mammalian collagenase by using .alpha.-phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof, and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 2, 1981
    Date of Patent: January 4, 1983
    Assignee: American Home Products Corporation
    Inventors: Donald E. Clark, Norman H. Grant
  • Inhibitors of mammalian collagenase
    Patent number: 4361574
    Abstract: A method of inhibiting mammalian collagenase by using 3-(p-substituted phenyl)-thiazolo[3,2-a]benzimidazole-2-alkanoic acids and esters thereof, and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 2, 1981
    Date of Patent: November 30, 1982
    Assignee: American Home Products Corporation
    Inventors: Norman H. Grant, Donald E. Clark
  • Antisecretory polypeptides
    Patent number: 4210636
    Abstract: Three polypeptides of the formulae [des-Ala.sup.1 -Gly.sup.2 ], Ala.sup.5, Ser.sup.6 -SRIF, Met.sup.7 -SRIF and [des-Ala.sup.1 -Gly.sup.2 -Lys.sup.4 ], (3-mercapto-1-oxopropyl).sup.3 -SRIF possessing gastric anti-secretory activity are useful anti-ulcer agents.
    Type: Grant
    Filed: May 17, 1978
    Date of Patent: July 1, 1980
    Assignee: American Home Products Corporation
    Inventors: Eric L. Lien, Dimitrios Sarantakis, Norman H. Grant
  • Pentapeptide with morphine- like activity
    Patent number: 4128541
    Abstract: The pentapeptide: H-Tyr-Gly-Gly-Phe-Ser-OH, or a non-toxic salt thereof, exerts an analgesic effect in rats by injection into the lateral brain ventricle.
    Type: Grant
    Filed: December 27, 1976
    Date of Patent: December 5, 1978
    Assignee: American Home Products Corporation
    Inventors: Dimitrios Sarantakis, Norman H. Grant
  • Method for stimulating release of prolactin
    Patent number: 4061737
    Abstract: Prolactin release is stimulated by parenteral administration of a pentapeptide of the formula:H-Tyr-Gly-Gly-Phe-Met-OH IorH-Tyr-Gly-Gly-Phe-Leu-OH IIor a non-toxic pharmacologically acceptable acid addition salt thereof.
    Type: Grant
    Filed: December 27, 1976
    Date of Patent: December 6, 1977
    Assignee: American Home Products Corporation
    Inventors: Harvey E. Alburn, Eric L. Lien, Norman H. Grant
  • Hydroxamic acids of alicyclic amino acids
    Patent number: 3997594
    Abstract: The compounds are hydroxamic acids of alicyclic amino acids, and esters of said compounds, all of which have valuable pharmacodynamic properties in that they suppress the immune response in warm-blooded animals.
    Type: Grant
    Filed: July 28, 1975
    Date of Patent: December 14, 1976
    Assignee: American Home Products Corporation
    Inventors: Harvey E. Alburn, Donald E. Clark, Norman H. Grant, Milton Lapidus
  • Amides of 1-aminocyclopentane carboxylic acid
    Patent number: 3981915
    Abstract: The compounds are amides of 1-aminocyclopentanecarboxylic acid, having valuable pharmacodynamic properties in that they are active against Columbia SK polio virus in warm-blooded animals.
    Type: Grant
    Filed: August 6, 1973
    Date of Patent: September 21, 1976
    Assignee: American Home Products Corporation
    Inventors: Harvey E. Alburn, Norman H. Grant
  • Amides of 1-aminocyclo-pentanecarboxylic acid
    Patent number: 3976692
    Abstract: The compounds are amides of 1-aminocyclopentanecarboxylic acid, having valuable pharmacodynamic properties in that they possess analgesic activity in warm-blooded animals.
    Type: Grant
    Filed: March 21, 1975
    Date of Patent: August 24, 1976
    Assignee: American Home Products Corporation
    Inventors: Harvey E. Alburn, Norman H. Grant