Abstract: A multi-framework blockchain service may be implemented with a common interface to manage different types of blockchain networks. Requests to create a blockchain network may be received via an interface for the control plane that triggers the creation of the blockchain network according to an identified workflow. Various operations to change the blockchain network, including membership changes, node additions, governance changes, analytics changes, and monitoring changes may be allowed or denied by the control plane according to a distributed governance policy in effect for the blockchain network.

Abstract: A method of recovering lithium from energy process water includes the steps of: removing alkaline earth metals from the water; passing the treated water through a reactor column containing a titanium oxide molecular sieve that adsorbs lithium ions; eluting the lithium ions from the molecular sieve using a strong acid solution; and collecting the resulting lithium-rich eluate fluid from the reactor column. The reactor column may include a diffuser core at the inlet tapered from a wider base to a narrow inner end as well as a first screen through which the fluid flows. Fluid exits the inner volume of the column through an outlet tube including a mounted end and walls that taper from the mounted end to a narrower tip; the walls include a second screen through which the fluid flows.

Abstract: A multi-framework blockchain service may be implemented with a common interface to manage different types of blockchain networks. Requests to create a blockchain network may be received via an interface for the control plane that triggers the creation of the blockchain network according to an identified workflow. Various operations to change the blockchain network, including membership changes, node additions, governance changes, analytics changes, and monitoring changes may be allowed or denied by the control plane according to a distributed governance policy in effect for the blockchain network.

Abstract: Various improvements for video production switchers are disclosed. In a user input module, a Link button is operable to link key functions with a user controllable input device. A multicolor lighting arrangement may be provided, and possibly calibrated, for illuminating each button of a switcher with a controllable color and/or intensity. In an improved Pulse-Width Modulation (PWM) scheme, a PWM output is dependent on a pseudo-random number and a threshold. A display on a keyer module may be used to provide indications of a key source and type currently associated with the keyer module. A switcher menu system may be enhanced by providing a first display for accessing a full menu system, and a second display for accessing at least a portion of the full menu system. In a modular switcher panel, a panel structure carries button modules, at least one of which is interchangeable without displacing other button modules.

Abstract: Various improvements for video production switchers are disclosed. In a user input module, a Link button is operable to link key functions with a user controllable input device. A multicolor lighting arrangement may be provided, and possibly calibrated, for illuminating each button of a switcher with a controllable color and/or intensity. In an improved Pulse-Width Modulation (PWM) scheme, a PWM output is dependent on a pseudo-random number and a threshold. A display on a keyer module may be used to provide indications of a key source and type currently associated with the keyer module. A switcher menu system may be enhanced by providing a first display for accessing a full menu system, and a second display for accessing at least a portion of the full menu system. In a modular switcher panel, a panel structure carries button modules, at least one of which is interchangeable without displacing other button modules.

Abstract: Compounds and methods are provided for treating patients suffering from health condition associated with an expression state of a gene such as fertility disorders, cancer, proliferative diseases, vascular diseases, wounds requiring therapeutic intervention, inflammation, and pulmonary disorders by administering to said patient a compound capable of modulating egr-1 and/or an egr-1 response element consensus sequence thereby altering the expression state of said gene. Also described are new methods for screening compounds to identify effectors of egr-1 and/or egr-1 consensus sequence elements and methods for treating patients by administering such effectors to modulate egr-1 and/or egr-1 consensus sequences to thereby modify expression of genes associated therewith to in turn treat diseases or other physiological conditions associated with such gene expression.

Abstract: The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.

Abstract: The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.

Abstract: Described are new methods for promoting the expression of apolipoprotein A1 (APO A1) for increasing levels of HDL, and assays for screening and identifying compounds for regulating expression of the APO A1 protein.

Abstract: Compounds comprising nitric oxide derivatives of stilbenes, polyphenols and flavonoids and methods of their use are provided for treating patients suffering from any of hypercholesterolemia, vascular oxidative stress and endothelial dysfunction.

Abstract: Compounds and methods are provided for treating patients suffering from any of hypercholesterolemia, vascular oxidative stress and endothelial dysfunction.

Abstract: Methods for treating disease and health conditions associated with the presence of TGF-? including cancers, are provided comprising administering a therapeutically effective agent which acts as a TGF-? antagonist and cathepsin B inhibitor or lymphocytes transformed with a gene for expressing such an agent for overcoming the lymphocyte evading effect of TGF-?.

Abstract: An integrated network management system for multiple networks of different topology domains employs hierarchical pass-through routing and multi-network service management through the network.