Patents by Inventor Okechukwu Ukairo

Okechukwu Ukairo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR STUDYING INFLAMMATION-DRUG INTERACTIONS
    Publication number: 20160363584
    Abstract: The present disclosure provides compositions, systems, and tools for modeling liver inflammation and methods of using the same. The disclosure provides micropatterned hepatocyte-Kupffer cell co-cultures or Kupffer cell-treated hepatocyte co-cultures where hepatocytes maintain Kupffer cell-initiated activities during long-term culture. The in vitro liver inflammation models of the present disclosure may be useful for evaluating both acute as well as chronic inflammation-mediated toxicities of compounds in a pre-clinical setting.
    Type: Application
    Filed: January 8, 2016
    Publication date: December 15, 2016
    Inventors: John K. McGeehan, Okechukwu Ukairo, Onyi Irrechukwu, Michael McVay
  • SYSTEMS AND METHODS FOR STUDYING INFLAMMATION-DRUG INTERACTIONS
    Publication number: 20130266939
    Abstract: The present disclosure provides compositions, systems, and tools for modeling liver inflammation and methods of using the same. The disclosure provides micropatterned hepatocyte co-cultures where individual cell populations remain functionally stable during long-term culture. The in vitro liver inflammation models of the present disclosure may be useful for evaluating inflammation-mediated toxicities of compounds in a pre-clinical setting.
    Type: Application
    Filed: March 12, 2013
    Publication date: October 10, 2013
    Applicant: HEPREGEN CORPORATION
    Inventors: Michael McVay, Chitra Kanchagar, Okechukwu Ukairo, Salman Khetani