Patents by Inventor Olaf Haeusler

Olaf Haeusler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF OCTENYL-SUCCINATE STARCHES AS A BINDER IN WET GRANULATION
    Publication number: 20220409546
    Abstract: The present invention relates to the use of octenyl succinate starch, in particular sodium octenyl succinate starch as a binder in wet granulation, in particular for pharmaceutical solid dosage form and the granule obtainable by the method thereof.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 29, 2022
    Inventors: Philippe LEFEVRE, Olaf HAEUSLER, Nicolas DESCAMPS, Gregory LE BIHAN
  • USE OF SODIUM OCTENYL-SUCCINATE STARCHES AS A BINDER IN CONTINUOUS WET GRANULATION
    Publication number: 20220387322
    Abstract: The present invention relates to the use of sodium octenyl succinate starch as a binder in twin screw granulation, in particular for pharmaceutical solid dosage form and the granule obtainable by the method thereof.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 8, 2022
    Inventors: Olaf HAEUSLER, Lise VANDEVIVERE
  • Glucose polymers for peritoneal dialysis
    Patent number: 11498939
    Abstract: The invention relates to a novel glucose polymer which is particularly useful for administration by the parenteral route, and to the method for the production thereof. The invention also relates to compositions comprising such a glucose polymer, and to the methods for the production thereof. The invention further relates to the use thereof as a medicament, for example as an osmotic agent for peritoneal dialysis.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: November 15, 2022
    Assignee: ROQUETTE FRERES
    Inventors: Denis Simon, Olaf Haeusler, Solène Bock
  • Use of particular combinations of carbohydrates for stabilizing proteins, and protein compositions containing such combinations
    Patent number: 10822372
    Abstract: One subject of the present invention is the use of a combination of a polyol (i) consisting of 12 carbon atoms and of a polyol (ii) consisting of 4 to 6 carbon atoms, as protein stabilizer. Another subject of the present invention is protein compositions comprising such a combination. A final subject of the present invention is a process for preparing protein compositions using such a combination.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: November 3, 2020
    Assignee: ROQUETTE FRERES
    Inventors: Merveille Nono, Nicolas Descamps, Denis Simon, Olaf Haeusler
  • NOVEL GLUCOSE POLYMERS FOR PERITONEAL DIALYSIS
    Publication number: 20190300558
    Abstract: The invention relates to a novel glucose polymer which is particularly useful for administration by the parenteral route, and to the method for the production thereof. The invention also relates to compositions comprising such a glucose polymer, and to the methods for the production thereof. The invention further relates to the use thereof as a medicament, for example as an osmotic agent for peritoneal dialysis.
    Type: Application
    Filed: September 14, 2017
    Publication date: October 3, 2019
    Inventors: Denis SIMON, Olaf HAEUSLER
  • USE OF PARTICULAR COMBINATIONS OF CARBOHYDRATES FOR STABILIZING PROTEINS, AND PROTEIN COMPOSITIONS CONTAINING SUCH COMBINATIONS
    Publication number: 20180118779
    Abstract: One subject of the present invention is the use of a combination of a polyol (i) consisting of 12 carbon atoms and of a polyol (ii) consisting of 4 to 6 carbon atoms, as protein stabilizer. Another subject of the present invention is protein compositions comprising such a combination. A final subject of the present invention is a process for preparing protein compositions using such a combination.
    Type: Application
    Filed: March 30, 2016
    Publication date: May 3, 2018
    Inventors: Merveille Nono, Nicolas Descamps, Denis Simon, Olaf Haeusler
  • Modified starch derivative-based matrix for colon targeting
    Patent number: 9358205
    Abstract: A controlled-release oral pharmaceutical composition of at least an active agent, including: a) a lipophilic matrix consisting of lipophilic compounds and/or amphiphilic compounds; and b) an hydrophilic matrix, wherein the hydrophilic matrix includes at least an indigestible polysaccharide, the active ingredient being dispersed in the lipophilic and/or the hydrophilic matrix. The present invention also relates to a process for the preparation of such a pharmaceutical composition.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: June 7, 2016
    Assignee: Roquette Freres
    Inventors: Olaf Haeusler, Marie-Helene DeGrave, Daniel Wils, Stefanie Krenzlin, Juergen Siepmann
  • Water insoluble polymer: indigestible water-soluble polysaccharide film coatings for colon targeting
    Patent number: 9107819
    Abstract: A controlled release pharmaceutical dosage form for controlled release of an active ingredient, includes an active ingredient coated by a polymeric mixture of: at least a water insoluble polymer; and at least an indigestible water-soluble oligosaccharide. The use and method of making the same are also described.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: August 18, 2015
    Assignee: ROQUETTE FRERES
    Inventors: Olaf Haeusler, Daniel Wils, Juergen Siepmann, Youness Karrout
  • MODIFIED STARCH DERIVATIVE-BASED MATRIX FOR COLON TARGETING
    Publication number: 20130202691
    Abstract: A controlled-release oral pharmaceutical composition of at least an active agent, including: a) a lipophilic matrix consisting of lipophilic compounds and/or amphiphilic compounds; and b) an hydrophilic matrix, wherein the hydrophilic matrix includes at least an indigestible polysaccharide, the active ingredient being dispersed in the lipophilic and/or the hydrophilic matrix. The present invention also relates to a process for the preparation of such a pharmaceutical composition.
    Type: Application
    Filed: October 28, 2011
    Publication date: August 8, 2013
    Applicant: ROQUETTE FRERES
    Inventors: Olaf Haeusler, Marie-Helene Degrave, Daniel Wils, Stefanie Krenzlin, Juergen Siepmann
  • WATER INSOLUBLE POLYMER: INDIGESTIBLE WATER-SOLUBLE POLYSACCHARIDE FILM COATINGS FOR COLON TARGETING
    Publication number: 20110256230
    Abstract: A controlled release pharmaceutical dosage form for controlled release of an active ingredient, includes an active ingredient coated by a polymeric mixture of: at least a water insoluble polymer; and at least an indigestible water-soluble oligosaccharide. The use and method of making the same are also described.
    Type: Application
    Filed: October 27, 2009
    Publication date: October 20, 2011
    Applicant: ROQUETTE FRERES
    Inventors: Olaf Haeusler, Daniel Wils, Juergen Siepmann, Youness Karrout
  • WATER INSOLUBLE POLYMER: STARCH-BASED FILM COATINGS FOR COLON TARGETING
    Publication number: 20110200680
    Abstract: A controlled release delivery dosage form for controlled release of an active ingredient, includes an active ingredient coated in a polymeric mixture of: at least a water insoluble polymer and a starch composition including at least one component selected from the group consisting of a starch having an amylose content of between 20 and 45%, a modified starch having an amylose content of between 50 and 80% and a legume starch. The present invention also relates to the use and method for making the same.
    Type: Application
    Filed: October 27, 2009
    Publication date: August 18, 2011
    Applicant: Roquette Freres
    Inventors: Olaf Haeusler, Daniel Wils, Juergen Siepmann, Youness Karrout