Abstract: Methods, apparatus, systems and articles of manufacture to make and/or process diagnostic tests are disclosed. An example test device, such as a lateral flow immunoassay device, includes a conjugate pad including conjugates for a target analyte; and a test grid including a plurality of zones in a two-dimensional grid, the test grid including: a first test zone in the plurality of zones including at least one of first immobilized antibodies or first immobilized antigens to attach to the target analyte labeled with a first conjugate of the conjugates; and a second test zone in the plurality of zones including at least one of second immobilized antibodies or second immobilized antigens to attach to the target analyte labeled with a second conjugate of the conjugates.

Abstract: The present invention relates to a sensor device and method for obtaining physiological information of a subject. The sensor device comprises a PPG sensor (20), a motion sensor (30) and a device (10) for obtaining physiological information of the subject. The device comprises a processing unit (13) for generating an output signal carrying physiological information by (i) modulating the motion reference signal on a carrier signal of the first set of carrier signals or on a second carrier signal orthogonal to the first set of carrier signals to obtain a modulated signal and combining the modulated signal with the modulated PPG signals to obtain the output signal or (ii) demodulating the modulated PPG signals, performing artifact-reduction on the demodulated PPG signals using the motion reference signal to obtain artifact-reduced PPG signals and modulating the artifact-reduced PPG signals on the first set of carrier signals to obtain the output signal.

Abstract: The present invention relates to a sensor device and method for obtaining physiological information of a subject. The sensor device comprises a PPG sensor (20), a motion sensor (30) and a device (10) for obtaining physiological information of the subject. The device comprises a processing unit (13) for generating an output signal carrying physiological information by (i) modulating the motion reference signal on a carrier signal of the first set of carrier signals or on a second carrier signal orthogonal to the first set of carrier signals to obtain a modulated signal and combining the modulated signal with the modulated PPG signals to obtain the output signal or (ii) demodulating the modulated PPG signals, performing artifact-reduction on the demodulated PPG signals using the motion reference signal to obtain artifact-reduced PPG signals and modulating the artifact-reduced PPG signals on the first set of carrier signals to obtain the output signal.

Abstract: The present invention relates to a patient monitoring system for monitoring cardio pulmonary performance or the like by means of capacitive measurement. Further the invention relates to a method for monitoring cardio pulmonary performance or the like by means of a capacitive measurement.

Abstract: The invention relates to a blood oximeter for measuring the oxygenation and at least one other parameter of flowing blood in living tissue. According to the invention, the blood oximeter comprises two lightsources (2, 3) emitting light of different wavelengths into tissue, and preferably a light detector (4) for detecting a transmitted and/or reflected part of the light emitted into the tissue, wherein at least one of the light sources is a laser with a laser cavity emitting a laser beam, the laser being adapted to allow a part of the laser beam which is scattered by the tissue to re-enter into the laser cavity, and wherein a laser beam sensor (7, 8) for measuring the light emitted from the laser is provided, the laser beam sensor (7, 8), thus, obtaining a signal which varies in accordance with the self-mixing interferometric effect between the original laser beam and the scattered laser beam.

Abstract: In a medical pulse oximetry sensor (10) at least two light emitting diodes (16, 18) are disposed to emit red light and infrared light through a portion of a subject's anatomy with a typically high oxygenated blood throughput. Typically, this area is also relatively narrow, to allow the light to pass through the area with acceptable attenuation, such as a finger or an earlobe. Light emitted from the LEDs (16, 18) is incumbent upon an integrated circuit (22) printed from a single CMOS substrate (21). The integrated circuit (22) includes all preprocessing and post-processing elements needed to convert the detected light signals into a pulse oximetry measurement. These elements include a photodetector (20), a photo pre-amplifier (40), a sampler/holder (42), an analog to digital converter (44), a microprocessor (46) a rangefinder (48), a timing control circuit (50) and an LED control circuit (52).

Abstract: The medical communication system comprises a plurality of medical identification devices (12). Each identification device (12) is attached to one particular patient (14). A registration processor generates a unique patient identification data that is stored in an electronic patient identification code memory (54). Each identification device (12) includes an intra-body wireless communication device (16) which transmits the patient's identification on the patient's body. A medical device (22), which is linked to the patient (14) to measure a vital function, periodically automatically receives the patient's identification code to continually ensure association to a correct patient.

Abstract: In order to provide a technique for determining high-quality blood pressure values of a patient, especially in cases of unsupervised blood pressure measurements in a home environment, it is suggested to use a system (1) for determining the blood pressure of a patient (2) comprising a blood pressure measuring device (3, 4) for measuring a blood pressure value, an auxiliary device (6, 7, 8, 9) for measuring the motor activity of the patient (2) during a defined period of time prior to the blood pressure measurement, and a processing device (13, 14), said processing device (13, 14) being adapted to obtain the motor activity information and the blood pressure value, said processing device (13, 14) being further adapted to automatically assess the blood pressure value using the motor activity information, and said processing device (13, 14) being further adapted to provide a measuring result depending on the result of the assessment.

Abstract: A modulator for a communications system includes a spread spectrum coder and a pulse code modulator having a signal input port connectable to a signal output port of the spread spectrum coder. The modulator performs a robust and error free modulation and coding scheme by using a modified spread spectrum scheme combined with pulse code modulation. The communication system contains a low data rate, noise robust modulation and coding scheme using a very simple transmitter. This results in a very straightforward transmitter circuit, reducing size and costs of the transmitter.

Abstract: The invention relates to a system and method for measuring bioelectrical signals of a user. Furthermore the invention relates to a computer program for measuring bioelectrical signals of a user. In order to provide a technique for measuring bioelectrical signals with reduced motion artefacts a new method is provided, comprising the steps of determining the displacement of an electrode, the electrode being adapted for measuring a bioelectrical signal, and adjusting the position of said electrode depending on the determined displacement. The present invention can be used in any system for measuring bioelectrical signals, which uses electrodes, e.g. in any ECG measurement system. With the reduction of artefacts according to the present invention the performance of all those systems can be substantially increased.

Abstract: A magnetic induction tomography system and method for studying the electromagnetic properties of an object includes generator coils adapted for generating a primary magnetic field, and sensor coils adapted for sensing a secondary magnetic field. Actuators provide relative movement between the generator coils and/or the sensor coils on the one hand and the object to be studied on the other hand.

Abstract: A system for monitoring a physiological condition of an individual. The system (1) comprises sensing means (3) arranged to pick up a first signal (M) in a first mode of the system, said first signal being representative of the physiological condition and to forward the first signal to a signal processing unit (33). The system comprises an actuatable control unit (2) positioned remote from the signal processing unit, the control unit (2) being suitable to generate a second signal (T) arranged to be superimposed on the first signal (M). The signal processing unit (33, 37) is arranged to decode the second signal and to make the system enter into a second mode upon receipt of the second signal (T).

Abstract: The invention provides a synthetic jet eductor pump that includes a synthetic jet actuator coupled to a fluid conduit. The synthetic jet actuator may include a vibratable membrane, an actuating portion that vibrates the vibratable membrane, a pump chamber coupled to the vibratable membrane, and a pump conduit in fluid communication with the pump chamber such that vibration of the membrane draws fluid into and ejects fluid from the pump conduit to create a net momentum of fluid in a predetermined direction. The fluid conduit may include a jet receiving portion between intake and ejection portions thereof, wherein the jet receiving portion is in fluid communication with the pump conduit. The net momentum of fluid created by the synthetic jet actuator may be communicated to the fluid conduit at the jet receiving portion to create fluid flow in the fluid conduit from the intake portion to the ejection portion.

Abstract: The invention relates to a blood oximeter for measuring the oxygenation and at least one other parameter of flowing blood in living tissue. According to the invention, the blood oximeter comprises two lightsources (2, 3) emitting light of different wavelengths into tissue, and preferably a light detector (4) for detecting a transmitted and/or reflected part of the light emitted into the tissue, wherein at least one of the light sources is a laser with a laser cavity emitting a laser beam, the laser being adapted to allow a part of the laser beam which is scattered by the tissue to re-enter into the laser cavity, and wherein a laser beam sensor (7, 8) for measuring the light emitted from the laser is provided, the laser beam sensor (7, 8), thus, obtaining a signal which varies in accordance with the self-mixing interferometric effect between the original laser beam and the scattered laser beam.

Abstract: Doppler radar sensor (3) is used for generating a reference or target signal (SR, ST), which can be used for positioning of measuring sensors (2) for acquiring a vital parameter of a subject (5). With the invention a simple and reliable technique for positioning sensors (2) is provided. Furthermore a simple and reliable technique for reproducing the position of sensors (2) is provided.

Abstract: The invention provides a device and system for measuring core (11) body temperature, comprising two pairs of temperature sensors (8-1a, 8-1b, 8-2a, 8-2b), with a structure (2, 3, 4, 5, 6, 7) therebetween, and a heat flux modulator (9) for changing the heat flux through one pair (8-1a, 8-1b) more than the heat flux through the other pair (8-2a, 8-2b). By measuring the temperatures for the two pairs of temperature sensors, the core (11) body temperature may be derived. This device allows more design freedom, and it is easier to manufacture and gives a more accurate core temperature.

Abstract: A pulse detector that uses electromagnetic waves for detecting a patient pulse in conjunction with the administration of defibrillation and/or CPR. Electromagnetic waves are applied to a patient blood vessel and the reflected electromagnetic waves are analyzed for a Doppler shift, which is indicative of a pulse. In some applications the pulse detector can be used as a stand-alone device in conjunction with the administration of CPR. In other applications, the pulse detector is included with a defibrillator and provides pulsatile information that is analyzed in addition to ECG information in determining resuscitation therapy, or following defibrillation to ascertain its success.

Abstract: Apparatus and method for sensing HO activity, and in particular blood glucose level based on an analyte level determination, the analyte being carboxyhemoglobin. In a preferred embodiment, HO activity and/or blood glucose level are extrapolated from Hb-CO level by determining an intermediate CO level. The apparatus and method are preferably non invasive.

Abstract: In a medical pulse oximetry sensor (10) at least two light emitting diodes (16, 18) are disposed to emit red light and infrared light through a portion of a subject's anatomy with a typically high oxygenated blood throughput. Typically, this area is also relatively narrow, to allow the light to pass through the area with acceptable attenuation, such as a finger or an earlobe. Light emitted from the LEDs (16, 18) is incumbent upon an integrated circuit (22) printed from a single CMOS substrate (21). The integrated circuit (22) includes all preprocessing and post-processing elements needed to convert the detected light signals into a pulse oximetry measurement. These elements include a photodetector (20), a photo pre-amplifier (40), a sampler/holder (42), an analog to digital converter (44), a microprocessor (46) a rangefinder (48), a timing control circuit (50) and an LED control circuit (52).

Abstract: The invention relates to the area of rehabilitation for patients with motor disabilities, especially for hemiplegic patients. With the present invention a long term, e.g. day and night, patient activity monitoring can be established in a home environment. A core idea of the invention is to evaluate the functional use of a limb by determining the synchronicity of the patient's movements depending on the movement's cyclicity. With this approach a reliable assessment of limb usage can be made based on the daily living activities of the patient. With the present invention the progress of rehabilitation can be monitored and guidance can be provided to therapists and patients about the state of the rehabilitation process. It further makes them aware of a lack of limb usage.