Abstract: The invention relates to an insert (1) for a thermostatic expansion valve as a thermostatic expansion valve (2) comprising such an insert and to a method of assembling such a thermostatic expansion valve (2). The insert (1) comprises an expansion valve element (3) and an expansion valve seat (4). The expansion valve element (3) is held inside the insert (1) by a biasing member (5), wherein the insert (1) is structured and arranged to be inserted into a valve housing (8). The task of the invention is to provide an insert for a thermostatic expansion valve that allows a simple assembly of the valve and also provides an improved functionality. The task is solved in that the insert (1) further comprises a control valve (12), wherein the control valve (12) is located in the same flow path through the insert (1) as the expansion valve seat (4).

Abstract: The present invention provides compounds useful for treating or preventing a brain-related disease or disorder. The present invention further provides a method of treating or preventing a brain-related disease or disorder in a patient, comprising administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of modulating the activity of a monoamine transporter.

Abstract: The present invention provides compounds useful for treating or preventing a brain-related disease or disorder. The present invention further provides a method of treating or preventing a brain-related disease or disorder in a patient, comprising administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of modulating the activity of a monoamine transporter.

Abstract: The present invention provides compounds useful for treating or preventing a brain-related disease or disorder. The present invention further provides a method of treating or preventing a brain-related disease or disorder in a patient, comprising administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of modulating the activity of a monoamine transporter.

Abstract: The invention relates to a solenoid valve with a housing as well as an inlet and an outlet, wherein the solenoid valve further comprises a valve element and an orifice, wherein the orifice comprises an orifice inlet and an orifice outlet. In order to increase the maximum operating pressure differential of the solenoid valve the orifice is provided in a membrane and the orifice has a diffuser characteristic in a direction from the orifice inlet to the orifice outlet.

Abstract: A method to manufacture a valve using metal injection moulding is disclosed. The valve housing comprises a welding cap for welding the upper part of the valve to the valve housing. The welding cap is placed so the upper part can be welding to the housing without damaging the inner cavity of the housing. There is a gab between the welding cap and the inner liner so the heat from the welding to not damage the inner liner allowing the inner parts of the valve to move freely.

Abstract: A refrigerant exchange arrangement is claimed with a first oil-trapping chamber (10) and a second oil-trapping chamber (11). A refrigerant exchange arrangement of simple construction is to be realised. For this purpose, the second oil-trapping chamber (11) is disposed within the first oil trapping chamber.