Abstract: A device for delivering foamed eye medication to an eye includes a housing defining an interior space for receiving liquid eye medication and air. A nozzle has a passage in fluid communication with the interior space. A foaming chamber is positioned within the interior space and in fluid communication with the nozzle. The air and liquid eye medication are mixed in the foaming chamber and exit the nozzle as foamed medication in response to pressurizing the interior space.

Abstract: Systems and methods are provided for determining a likelihood that a drop released from a bottle will land in an eye of a user. Each of an eye of a user and a tip of a bottle and illuminated and imaged to provide at least one image. An orientation of the bottle is determined via an inertial measurement unit, and a likelihood that a drop released from the bottle will land in the eye of the user is determined from the determined orientation and the at least one image.

Abstract: An eye sprayer includes a spray nozzle having a nozzle axis. the spray nozzle is configured to produce eye spray. The eye sprayer also includes a concave mirror with an opening configured to allow for the delivery eye spray from the spray nozzle. The eye sprayer further includes a light emitter configured to produce a visible light beam directed from the mirror along the nozzle axis.

Abstract: An eye drop monitoring device for monitoring gravity-driven placement of an eye drop into an eye of a patient includes a light source configured to selectively direct light toward at least one of the eye and the eye drop. The light is backscattered by at least one of the eye and the eye drop. A light detector is configured to detect the backscattered light from at least one of the eye and the eye drop and responsively produce at least one backscatter signal. An accelerometer is configured to determine a spatial position of the device and responsively produce a device position signal. A processing unit is configured to receive the at least one backscatter signal and the device position signal and responsively produce a drop-on-target signal indicative of a likelihood that the eye drop fell into a predetermined position with respect to the eye.

Abstract: An intraocular pressure sensing element along with implant microelectronic circuitry to be configured to be implanted into an eye of a user. The microelectronic circuitry is conductively coupled to the intraocular pressure sensing element to produce measured pressure data. A microscopic light emitting diode, LED, that is also implanted into the eye, is driven with the measured pressure data thereby optically transmitting the measured pressure data for communication with outside of the eye. A photovoltaic element that is also implanted into the eye supplies energy to operate the implant microelectronic circuitry and the microscopic LED. Other aspects are also described and claimed.

Abstract: An intraocular pressure (IOP) measurement system. An optical pressure sensor is implantable in the cornea of an eye, wherein the sensor has a sealed cavity that changes shape as a function of IOP of the eye. An optical transmitter that is outside of the eye emits an incident optical beam. A receiver that is also outside of the eye produces an output signal in response to receiving reflections of the incident beam from the sensor. A processor is configured to estimate the IOP of the eye based on processing the output signal of the receiver. Other aspects are also described and claimed.

Abstract: According to one embodiment, an intraocular pressure measurement system includes a pressure sensor implantable in an eye and comprising an optical cavity with an optical cavity depth that varies based on an intraocular pressure of the eye. The system further includes an external device for emitting light and measuring intraocular pressure based on reflected light. In an embodiment, the external device includes a light source configured to emit a plurality of beams, and a spectrometer configured to receive light reflected from at least two beams and produce an output based on the light reflected from the at least two beams. The output varies based on the depth of the optical cavity. The external device further includes a processor configured to receive the output and, based on the output, estimate the intraocular pressure of the eye.

Abstract: A two-photon imaging system capable of imaging of an image region in real time is presented. The imaging system comprises a source of excitation light that provides the excitation light as a plurality of laser beamlets. The plurality of laser beamlets is collectively scanned by a single-axis scanner along a first direction in the focal plane of the image region and oriented such that neither the rows nor columns are aligned with the first direction. As a result, each laser beamlet scans a different sub-region of the image region and the plurality of sub-regions are simultaneously scanned. As a result, the entirety of the image region is scanned in the same amount of time required to scan one image sub-region.

Abstract: A multi-foci laser scanning microscope generates a set of time-multiplexed beams that are simultaneously scanned over multiple scan areas of the sample to be observed. A photodetector array associated with the beams detect fluorescence signals from the sample. A processor processes output signals from the photodetector array based on the time-multiplexing of the beams to provide a much wider field of view and reduced crosstalk between neighboring scan areas for more accurate imaging.

Abstract: A two-photon imaging system capable of imaging of an image region in real time is presented. The imaging system comprises a source of excitation light that provides the excitation light as a plurality of laser beamlets. The plurality of laser beamlets is collectively scanned by a single-axis scanner along a first direction in the focal plane of the image region and oriented such that neither the rows nor columns are aligned with the first direction. As a result, each laser beamlet scans a different sub-region of the image region and the plurality of sub-regions are simultaneously scanned. As a result, the entirety of the image region is scanned in the same amount of time required to scan one image sub-region.

Abstract: A multi-foci laser scanning microscope generates a set of time-multiplexed beams that are simultaneously scanned over multiple scan areas of the sample to be observed. A photodetector array associated with the beams detect fluorescence signals from the sample. A processor processes output signals from the photodetector array based on the time-multiplexing of the beams to provide a much wider field of view and reduced crosstalk between neighboring scan areas for more accurate imaging.