Patents by Inventor Oleksiy Itsenko

Oleksiy Itsenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for the use of [C] carbon monoxide in labeling synthesis by photo-initiated carbonylation
    Patent number: 8282888
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Grant
    Filed: April 14, 2009
    Date of Patent: October 9, 2012
    Assignee: GE Healthcare Limited
    Inventors: Tor Kihlberg, Oleksiy Itsenko, Tommy Ferm, Bengt Langstrom
  • Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled ketones by photo-induced free radical carbonylation
    Patent number: 8273861
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with carbanion precursors pretreated by a base are provided. The resultant carbon-isotope labeled ketones, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits and method for PET studies are also provided.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: September 25, 2012
    Assignee: GE Healthcare Limited
    Inventors: Bengt Langstrom, Oleksiy Itsenko, Tor Kihlberg
  • Method for the use of [C]carbon monoxide in labeling synthesis of C-labelled acids by photo-induced free radical carbonylation under mild conditions using sulfoxides
    Patent number: 8232424
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with sulfoxides and triethylamine are provided. The resultant carbon-isotope labeled acids, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits and method for PET studies are also provided.
    Type: Grant
    Filed: June 14, 2006
    Date of Patent: July 31, 2012
    Assignee: GE Healthcare Limited
    Inventors: Bengt Langstrom, Oleksiy Itsenko
  • Method for the use of [C] carbon monoxide in labeling synthesis of C-labelled amides using metal amides and photo-induced free radical carbonylation
    Patent number: 8129528
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using weakly nucleophilic amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: March 6, 2012
    Assignee: GE Healthcare Limited
    Inventors: Oleksiy Itsenko, Tor Kihlberg, Bengt Langstrom
  • METHOD FOR THE USE OF [11C] CARBON MONOXIDE IN LABELING SYNTHESIS OF 11C-LABELLED ESTERS AND ACIDS BY SENSITIZED PHOTO-INDUCED FREE RADICAL CARBONYLATION
    Publication number: 20100158804
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with alcohols or water treated by photosensitizers are provided. The resultant carbon-isotope labeled esters and acids, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits and method for PET studies are also provided.
    Type: Application
    Filed: March 2, 2010
    Publication date: June 24, 2010
    Applicant: GE HEALTHCARE LIMITED
    Inventors: BENGT LANGSTROM, OLEKSIY ITSENKO
  • METHOD FOR THE USE OF [11C] CARBON MONOXIDE IN LABELING SYNTHESIS OF 11C-LABELLED ESTERS BY PHOTO-INDUCED FREE RADICAL CARBONYLATION
    Publication number: 20100061931
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with alcohols pretreated by a base are provided. The resultant carbon-isotope labeled esters are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Application
    Filed: November 19, 2009
    Publication date: March 11, 2010
    Inventors: Bengt Langstrom, Oleksiy Itsenko, Tor Kihlberg
  • Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled acids by photo-induced free radical carbonylation
    Patent number: 7667011
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with water pretreated by a base are provided. The resultant carbon-isotope labeled acids are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: February 23, 2010
    Inventors: Bengt Langstrom, Oleksiy Itsenko
  • METHOD FOR THE USE OF [11C] CARBON MONOXIDE IN LABELING SYNTHESIS OF 11C-LABELLED AMIDES USING METAL AMIDES AND PHOT-INDUCED FREE RADICAL CARBONYLATION
    Publication number: 20090297445
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using weakly nucleophilic amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Application
    Filed: June 4, 2009
    Publication date: December 3, 2009
    Inventors: Oleksiy Itsenko, Tor Kihlberg, Bengt Langstrom
  • Method for the use of [C] carbon monoxide in labeling synthesis of C-labelled esters by photo-induced free radical carbonylation
    Patent number: 7626052
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with alcohols pretreated by a base are provided. The resultant carbon-isotope labeled esters are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: December 1, 2009
    Assignee: GE Healthcare Limited
    Inventors: Bengt Langstrom, Oleksiy Itsenko, Tor Kihlberg
  • METHOD FOR THE USE OF [11C] CARBON MONOXIDE IN LABELING SYNTHESIS OF 11C-LABELLED KETONES BY PHOTO-INDUCED FREE RADICAL CARBONYLATION
    Publication number: 20090208414
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with carbanion precursors pretreated by a base are provided. The resultant carbon-isotope labeled ketones, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits and method for PET studies are also provided.
    Type: Application
    Filed: August 29, 2006
    Publication date: August 20, 2009
    Inventors: Bengt Langstrom, Oleksiy Itsenko, Tor Kihlberg
  • Method and apparatus for the use of [11C] Carbon Monoxide in Labeling Synthesis by Photo-Initiated Carbonylation
    Publication number: 20090203909
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Application
    Filed: April 14, 2009
    Publication date: August 13, 2009
    Inventors: Tor Kihlberg, Oleksiy Itsenko, Tommy Ferm, Bengt Langstrom
  • Method for the use of [C] carbon monoxide in labeling synthesis of C-labelled amides using metal amides and photo-induced free radical carbonylation
    Patent number: 7553942
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using weakly nucleophilic amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: June 30, 2009
    Assignee: GE Healthcare Limited
    Inventors: Oleksiy Itsenko, Tor Kihlberg, Bengt Langstrom
  • Method and apparatus for the use of [C] carbon monoxide in labeling synthesis by photo-initiated carbonylation
    Patent number: 7521544
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Grant
    Filed: October 25, 2004
    Date of Patent: April 21, 2009
    Assignee: GE Healthcare Limited
    Inventors: Tor Kihlberg, Oleksiy Itsenko, Tommy Ferm, Bengt Langstrom
  • Method for the Use of [11C] Carbon Monoxide in Labeling Synthesis of 11C-Labelled Esters and Acids by Sensitized Photo-Induced Free Radical
    Publication number: 20080226555
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with alcohols or water treated by photosensitizers are provided. The resultant carbon-isotope labeled esters and acids, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits and method for PET studies are also provided.
    Type: Application
    Filed: June 5, 2006
    Publication date: September 18, 2008
    Inventors: Bengt Langstrom, Oleksiy Itsenko
  • Method for the Use of [11C]Carbon Monoxide in Labeling Synthesis of 11C-Labelled Acids by Photo-Induced Free Radical Carbonylation Under Mild Conditions Using Sulfoxides
    Publication number: 20080206147
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with sulfoxides and triethylamine are provided. The resultant carbon-isotope labeled acids, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits and method for PET studies are also provided.
    Type: Application
    Filed: June 14, 2006
    Publication date: August 28, 2008
    Inventors: Bengt Langstrom, Oleksiy Itsenko
  • Method and apparatus for the use of [11c] carbon monoxide in labeling synthesis by photo-intiated carbonylation
    Publication number: 20070043213
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Application
    Filed: October 25, 2004
    Publication date: February 22, 2007
    Inventors: Tor Kihlberg, Oleksiy Itsenko, Tommy Ferm, Bengt Langstrom
  • Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled compounds by thermally induced free radical carbonylation
    Publication number: 20060171882
    Abstract: Methods and reagents for thermally initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with nucleophiles are provided. The resultant carbon-isotope labeled compounds are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Application
    Filed: February 1, 2006
    Publication date: August 3, 2006
    Inventors: Bengt Langstrom, Oleksiy Itsenko, Tor Kihlberg
  • Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled esters by photo-induced free radical carbonylation
    Publication number: 20060165590
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with alcohols pretreated by a base are provided. The resultant carbon-isotope labeled esters are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Application
    Filed: December 14, 2005
    Publication date: July 27, 2006
    Inventors: Bengt Langstrom, Oleksiy Itsenko, Tor Kihlberg
  • Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled acids by photo-induced free radical carbonylation
    Publication number: 20060159608
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with water pretreated by a base are provided. The resultant carbon-isotope labeled acids are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Application
    Filed: December 5, 2005
    Publication date: July 20, 2006
    Inventors: Bengt Langstrom, Oleksiy Itsenko
  • Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled amides using metal amides and photo-induced free radical carbonylation
    Publication number: 20060133998
    Abstract: Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using weakly nucleophilic amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
    Type: Application
    Filed: November 7, 2005
    Publication date: June 22, 2006
    Inventors: Oleksiy Itsenko, Tor Kihlberg, Bengt Langstrom