Patents by Inventor Olga AB

Olga AB has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FOLATE RECEPTOR 1 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREOF
    Publication number: 20240132585
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Application
    Filed: September 8, 2023
    Publication date: April 25, 2024
    Applicant: ImmunoGen, Inc.
    Inventors: Olga AB, Daniel TAVARES, Lingyun RUI, Gillian PAYNE, Viktor S. GOLDMAKER
  • Method for increasing the efficacy of cancer therapy by administering an anti-FOLR1 immunoconjugate
    Patent number: 11932701
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: March 19, 2024
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Julianto Setiady, Sharron Ladd, Christina N. Carrigan, Lingyun Rui
  • Biparatopic FR-alpha antibodies and immunoconjugates
    Patent number: 11834498
    Abstract: The present disclosure provides biparatopic antibodies comprising polypeptides that bind to folate receptor alpha (FR?) compositions comprising such biparatopic antibodies. In a specific aspect, the biparatopic antibodies bind to FR? and modulate FR? activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering a biparatopic antibody that specifically binds to FR? and modulates FR? activity.
    Type: Grant
    Filed: June 10, 2022
    Date of Patent: December 5, 2023
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Neeraj Kohli, Thomas Chittenden, Julianto Setiady
  • DIAGNOSTIC ASSAYS AND KITS FOR DETECTION OF FOLATE RECEPTOR 1
    Publication number: 20230213524
    Abstract: The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Application
    Filed: June 2, 2022
    Publication date: July 6, 2023
    Inventors: Christina N. CARRIGAN, Olga AB, Daniel TAVARES, Beni B. WOLF, Nathan E. TESTA
  • BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20230085779
    Abstract: The present disclosure provides biparatopic antibodies comprising polypeptides that bind to folate receptor alpha (FR?) compositions comprising such biparatopic antibodies. In a specific aspect, the biparatopic antibodies bind to FR? and modulate FR? activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering a biparatopic antibody that specifically binds to FR? and modulates FR? activity.
    Type: Application
    Filed: June 10, 2022
    Publication date: March 23, 2023
    Inventors: Olga AB, Neeraj Kohli, Thomas Chittenden, Julianto Setiady
  • Anti-FOLR1 Immunoconjugate Dosing Regimens
    Publication number: 20220378694
    Abstract: Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.
    Type: Application
    Filed: April 14, 2022
    Publication date: December 1, 2022
    Applicant: ImmunoGen, Inc.
    Inventors: Kelli Running, Robert A. Mastico, James J. O'Leary, Olga AB, Beni Wolf
  • Biparatopic FR-? antibodies and immunoconjugates
    Patent number: 11396543
    Abstract: The present disclosure provides biparatopic antibodies comprising polypeptides that bind to folate receptor alpha (FR?) compositions comprising such biparatopic antibodies. In a specific aspect, the biparatopic antibodies bind to FR? and modulate FR? activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering a biparatopic antibody that specifically binds to FR? and modulates FR? activity.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: July 26, 2022
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Neeraj Kohli, Thomas Chittenden, Julianto Setiady
  • ANTIBODIES AND ASSAYS FOR DETECTION OF FOLATE RECEPTOR 1
    Publication number: 20220169745
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Application
    Filed: November 10, 2021
    Publication date: June 2, 2022
    Inventors: Olga AB, Daniel TAVARES, Julianto SETIADY, Sharron LADD, Christina N. CARRIGAN, Lingyun RUI
  • Method for identifying an ovarian cancer in a subject likely to respond to anti-folate receptor 1 (FOLR1) antibody
    Patent number: 11198736
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: December 14, 2021
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Juliantro Setiady, Sharron Ladd, Christina N. Carrigan, Lingyun Rui
  • Folate Receptor 1 Antibodies and Immunoconjugates and Uses Thereof
    Publication number: 20210032327
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Application
    Filed: July 21, 2020
    Publication date: February 4, 2021
    Applicant: ImmunoGen, Inc.
    Inventors: Olga AB, Daniel Tavares, Lingyun Rui, Gillian Payne, Viktor S. Goldmakher
  • BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20200362029
    Abstract: The present disclosure provides biparatopic antibodies comprising polypeptides that bind to folate receptor alpha (FR?) compositions comprising such biparatopic antibodies. In a specific aspect, the biparatopic antibodies bind to FR? and modulate FR? activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering a biparatopic antibody that specifically binds to FR? and modulates FR? activity.
    Type: Application
    Filed: April 28, 2020
    Publication date: November 19, 2020
    Inventors: Olga AB, Neeraj KOHLI, Thomas CHITTENDEN, Julianto SETIADY
  • Diagnostic Assays and Kits for Detection of Folate Receptor 1
    Publication number: 20200333347
    Abstract: The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Application
    Filed: February 28, 2020
    Publication date: October 22, 2020
    Inventors: Christina N. CARRIGAN, Olga AB, Daniel TAVARES, Beni B. WOLF, Nathan E. TESTA
  • ANTIBODIES AND ASSAYS FOR DETECTION OF FOLATE RECEPTOR 1
    Publication number: 20200325240
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Application
    Filed: December 9, 2019
    Publication date: October 15, 2020
    Inventors: Olga AB, Daniel TAVARES, Julianto SETIADY, Sharron LADD, Christina N. CARRIGAN, Lingyun RUI
  • Folate receptor 1 antibodies and immunoconjugates and uses thereof
    Patent number: 10752683
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: August 25, 2020
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Lingyun Rui, Gillian Payne, Viktor S. Goldmakher
  • Diagnostic assays and kits for detection of folate receptor 1
    Patent number: 10613093
    Abstract: The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: April 7, 2020
    Assignee: ImmunoGen, Inc.
    Inventors: Christina N. Carrigan, Olga Ab, Daniel Tavares, Beni B. Wolf
  • Anti-FOLR1 Immunoconjugate Dosing Regimens
    Publication number: 20200046634
    Abstract: Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.
    Type: Application
    Filed: April 19, 2019
    Publication date: February 13, 2020
    Applicant: ImmunoGen, Inc.
    Inventors: Kelli RUNNING, Robert A. MASTICO, James J. O'LEARY, Olga AB, Beni WOLF
  • Methods of using antibodies to detect folate receptor 1 (FOLR1)
    Patent number: 10544230
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: January 28, 2020
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Julianto Setiady, Sharron Ladd, Christina N. Carrigan, Lingyun Rui
  • Folate Receptor 1 Antibodies and Immunoconjugates and Uses Thereof
    Publication number: 20190345248
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Application
    Filed: April 15, 2019
    Publication date: November 14, 2019
    Applicant: ImmunoGen, Inc.
    Inventors: Olga AB, Daniel TAVARES, Lingyun RUI, Gillian PAYNE, Viktor S. GOLDMAKHER
  • Diagnostic Assays and Kits for Detection of Folate Receptor 1
    Publication number: 20190227073
    Abstract: The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Application
    Filed: November 28, 2018
    Publication date: July 25, 2019
    Inventors: Christina N. Carrigan, Olga Ab, Daniel Tavares, Beni B. Wolf
  • Folate receptor 1 antibodies and immunoconjugates and uses thereof
    Patent number: 10301385
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: May 28, 2019
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Lingyun Rui, Gillian Payne, Viktor S. Goldmakher