Patents by Inventor Oliver Gene McDonald

Oliver Gene McDonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Haplotyping method for multiple distal nucleotide polymorphisms
    Patent number: 7041447
    Abstract: The invention relates to methods for detecting genetic polymorphisms in an organism, particularly to the detection of genetic polymorphisms that are due to multiple distal nucleotide polymorphisms within a gene. Methods are provided for determining the haplotype structure of a gene, or other contiguous DNA segment, having two or more nucleotide polymorphisms that are separated by kilobases of DNA. The methods involve the use of PCR amplification and DNA ligation to bring the nucleotide polymorphisms on a particular allele of the gene into close proximity to facilitate the determination of haplotype structure.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: May 9, 2006
    Assignee: St. Jude Children's Hospital, Inc.
    Inventors: William Edward Evans, Oliver Gene McDonald
  • Haplotyping method for multiple distal nucleotide polymorphisms
    Publication number: 20020081598
    Abstract: The invention relates to methods for detecting genetic polymorphisms in an organism, particularly to the detection of genetic polymorphisms that are due to multiple distal nucleotide polymorphisms within a gene. Methods are provided for determining the haplotype structure of a gene, or other contiguous DNA segment, having two or more nucleotide polymorphisms that are separated by kilobases of DNA. The methods involve the use of PCR amplification and DNA ligation to bring the nucleotide polymorphisms on a particular allele of the gene into close proximity to facilitate the determination of haplotype structure.
    Type: Application
    Filed: April 9, 2001
    Publication date: June 27, 2002
    Inventors: William Edward Evans, Oliver Gene McDonald