Patents by Inventor Oliver Hardick
Oliver Hardick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11913918Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.Type: GrantFiled: May 5, 2022Date of Patent: February 27, 2024Assignee: PURIDIFY LTD.Inventors: Michael Williams, Iwan Roberts, Oliver Hardick, Matthew Townsend, Christopher Morris, Shameer Subratty
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Publication number: 20220268745Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.Type: ApplicationFiled: May 5, 2022Publication date: August 25, 2022Inventors: Michael Williams, Iwan Roberts, Oliver Hardick, Matthew Townsend, Christopher Morris, Shameer Subratty
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Patent number: 11353433Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.Type: GrantFiled: August 25, 2017Date of Patent: June 7, 2022Assignee: PURIDIFY LTD.Inventors: Michael Williams, Iwan Roberts, Oliver Hardick, Matthew Townsend, Christopher Morris, Shameer Subratty
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Publication number: 20210162370Abstract: The present invention provides a process for preparing a functionalised polymeric chromatography medium, which process comprises (I) providing two or more non-woven sheets stacked one on top of the other, each said sheet comprising one or more polymer nanofibres, (II) simultaneously heating and pressing the stack of sheets to fuse points of contact between the nanofibres of adjacent sheets, and (III) contacting the pressed and heated product with a reagent which functionalises the product of step (II) as a chromatography medium.Type: ApplicationFiled: October 23, 2020Publication date: June 3, 2021Inventors: Oliver Hardick, Daniel Gilbert Bracewell, Stewart Dods
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Patent number: 11008364Abstract: The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibres which in use form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same.Type: GrantFiled: June 23, 2020Date of Patent: May 18, 2021Assignee: Puridify Ltd.Inventors: Daniel Gilbert Bracewell, Robert Stevens, Oliver Hardick
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Publication number: 20200392179Abstract: The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibres which in use form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same.Type: ApplicationFiled: June 23, 2020Publication date: December 17, 2020Inventors: Daniel Gilbert Bracewell, Robert Stevens, Oliver Hardick
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Patent number: 10850259Abstract: The present invention provides a process for preparing a functionalised polymeric chromatography medium, which process comprises (I) providing two or more non-woven sheets stacked one on top of the other, each said sheet comprising one or more polymer nanofibres, (II) simultaneously heating and pressing the stack of sheets to fuse points of contact between the nanofibres of adjacent sheets, and (III) contacting the pressed and heated product with a reagent which functionalises the product of step (II) as a chromatography medium.Type: GrantFiled: April 5, 2016Date of Patent: December 1, 2020Assignee: Puridify Ltd.Inventors: Oliver Hardick, Daniel Gilbert Bracewell, Stewart Dods
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Patent number: 10696714Abstract: The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibres which in use form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same.Type: GrantFiled: May 24, 2019Date of Patent: June 30, 2020Assignee: PURIDIFY, LTD.Inventors: Daniel Gilbert Bracewell, Robert Stevens, Oliver Hardick
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Publication number: 20190276491Abstract: The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibres which in use form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same.Type: ApplicationFiled: May 24, 2019Publication date: September 12, 2019Inventors: Daniel Gilbert Bracewell, Robert Stevens, Oliver Hardick
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Publication number: 20190234914Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.Type: ApplicationFiled: August 25, 2017Publication date: August 1, 2019Applicant: Puridify Ltd.Inventors: Michael Williams, Iwan Roberts, Oliver Hardick, Matthew Townsend, Christopher Morris, Shameer Subratty
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Patent number: 10344051Abstract: The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibers which in use form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same.Type: GrantFiled: September 25, 2017Date of Patent: July 9, 2019Assignee: Puridify Ltd.Inventors: Daniel Gilbert Bracewell, Robert Stevens, Oliver Hardick
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Publication number: 20180094022Abstract: The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibres which in use form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same.Type: ApplicationFiled: September 25, 2017Publication date: April 5, 2018Inventors: Daniel Gilbert Bracewell, Robert Stevens, Oliver Hardick
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Patent number: 9802979Abstract: The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibers which form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same in chromatography, such as the isolation of recombinant proteins, monoclonal antibodies, viral vaccines and plasmid DNA. The invention further provides for the use of the chromatographic medium in a simulated moving bed system.Type: GrantFiled: November 7, 2012Date of Patent: October 31, 2017Assignee: Puridify Ltd.Inventors: Daniel Gilbert Bracewell, Robert Stevens, Oliver Hardick
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Publication number: 20160288089Abstract: The present invention provides a process for preparing a functionalised polymeric chromatography medium, which process comprises (I) providing two or more non-woven sheets stacked one on top of the other, each said sheet comprising one or more polymer nanofibres, (II) simultaneously heating and pressing the stack of sheets to fuse points of contact between the nanofibres of adjacent sheets, and (III) contacting the pressed and heated product with a reagent which functionalises the product of step (II) as a chromatography medium.Type: ApplicationFiled: April 5, 2016Publication date: October 6, 2016Inventors: Oliver Hardick, Daniel Gilbert Bracewell, Stewart Dods
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Publication number: 20140296464Abstract: The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibres which form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same in chromatography, such as the isolation of recombinant proteins, monoclonal antibodies, viral vaccines and plasmid DNA. The invention further provides for the use of the chromatographic medium in a simulated moving bed system.Type: ApplicationFiled: November 7, 2012Publication date: October 2, 2014Applicant: UCL BUSINESS PLCInventors: Daniel Gilbert Bracewell, Robert Stevens, Oliver Hardick