Patents by Inventor Oliver Politz

Oliver Politz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-amino-N-[7-methoxy-2, 3-dihydroimidazo-[1,2-c] quinazolin-5-yl] pyrimidine-5-carboxamides
    Patent number: 10844066
    Abstract: This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: November 24, 2020
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Thomas Schwarz, Ningshu Liu, Oliver Politz, Michael Gerisch, Dieter Lang
  • 2-AMINO-N- [7-METHOXY-2, 3-DIHYDROIMIDAZO-[1, 2-C] QUINAZOLIN-5-YL] PYRIMIDINE-5-CARBOXAMIDES
    Publication number: 20190092775
    Abstract: This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: March 1, 2017
    Publication date: March 28, 2019
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Thomas SCHWARZ, Ningshu LIU, Oliver POLITZ, Michael GERISCH, Dieter LANG
  • Imidazopyridazines as Akt kinase inhibitors
    Patent number: 9604989
    Abstract: The present invention relates to a method for the treatment of a cancer that is sensitive to Pi3K/Akt pathway inhibition by administering a therapeutically effective amount of a compound of formula (I)
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: March 28, 2017
    Assignees: BAYER INTELLECTUAL PROPERTY GMBH, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Lars Bärfacker, William Scott, Andrea Hägebarth, Stuart Ince, Hartmut Rehwinkel, Oliver Politz, Roland Neuhaus, Hans Briem, Ulf Bömer
  • Substituted pyrazolopyrimidines as Akt kinase inhibitors
    Patent number: 9370517
    Abstract: Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: June 21, 2016
    Assignees: Bayer Intellectual Property GmbH, Bayer Pharma Aktiengesselschaft
    Inventors: Lars Bärfacker, William Scott, Andrea Hägebarth, Hartmut Rehwinkel, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • Substituted imidazopyrazines as Akt kinase inhibitors
    Patent number: 9260435
    Abstract: Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: February 16, 2016
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Lars Bärfacker, William Scott, Andrea Hägebarth, Stuart Ince, Hartmut Rehwinkel, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS
    Publication number: 20150368250
    Abstract: Imidazopyridazines of formula (I) a process for their production and the use thereof.
    Type: Application
    Filed: July 6, 2015
    Publication date: December 24, 2015
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Lars BÄRFACKER, William SCOTT, Andrea HÄGEBARTH, Stuart INCE, Hartmut REHWINKEL, Oliver POLITZ, Roland NEUHAUS, Hans BRIEM, Ulf BÖMER
  • Imidazopyridazines as Akt kinase inhibitors
    Patent number: 9206185
    Abstract: The application relates to imidazopyridazines of formula (I) which are useful as Akt inhibitors suitable for the treatment of cancer, and processes for their production and the use thereof.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: December 8, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Lars Bärfacker, William Scott, Andrea Hägebarth, Stuart Ince, Hartmut Rehwinkel, Oliver Politz, Roland Neuhaus, Hans Briem, Ulf Bömer
  • SUBSTITUTED PYRAZOLOPYRIMIDINES AS AKT KINASE INHIBITORS
    Publication number: 20150306102
    Abstract: Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: January 8, 2013
    Publication date: October 29, 2015
    Applicants: BAYER INTELLECTUAL PROPERTY GMBH, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Lars BÄRFACKER, William SCOTT, Andrea HÄGEBARTH, Hartmut REHWINKEL, Oliver POLITZ, Roland NEUHAUS, Ulf BÖMER
  • Substituted imidazo[1,2-B]pyridazines
    Patent number: 8987273
    Abstract: The invention relates to imidazo[1,2-b]pyridazines of general formula (I) a process for their manufacture and their use for the treatment of benign and malignant neoplasia.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: March 24, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hartmut Rehwinkel, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • Substituted pyrimido[1,2-b]indazoles and their use as modulators of the Pi3K/Akt pathway
    Patent number: 8987286
    Abstract: Compounds of Formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. The compounds of formula (I) a: useful for the treatment of cancer.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: March 24, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hartmut Rehwinkel, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • Substituted imidazo[1,2-a]pyrimidines and —pyridines
    Patent number: 8975265
    Abstract: Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: March 10, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stuart Ince, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer, William Scott
  • SUBSTITUTED IMIDAZOPYRAZINES AS AKT KINASE INHIBITORS
    Publication number: 20150005309
    Abstract: Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: January 8, 2013
    Publication date: January 1, 2015
    Inventors: Lars Bärfacker, William Scott, Andrea Hägebarth, Stuart Ince, Hartmut Rehwinkel, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS
    Publication number: 20140113901
    Abstract: Imidazopyridazines of formula (I) a process for their production and the use thereof.
    Type: Application
    Filed: April 7, 2011
    Publication date: April 24, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Lars Bärfacker, William Sott, Andrea Hägebarth, Stuart Ince, Hartmut Rehwinkel, Oliver Politz, Roland Neuhaus, Hans Briem, Ulf Bömer
  • SUBSTITUTED PYRIMIDO[1,2-B]INDAZOLES AND THEIR USE AS MODULATORS OF THE PI3K/AKT PATHWAY
    Publication number: 20130310405
    Abstract: Compounds of Formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. The compounds of formula (I) a: useful for the treatment of cancer.
    Type: Application
    Filed: December 13, 2011
    Publication date: November 21, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Hartmut Rehwinkel, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES
    Publication number: 20130210825
    Abstract: The invention relates to imidazo[1,2-b]pyridazines of general formula (I) a process for their manufacuture and their use for the treatment of benign and malignant neoplasia.
    Type: Application
    Filed: July 27, 2011
    Publication date: August 15, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GmbH
    Inventors: Hartmut Rehwinkel, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • Substituted Imidazo[1,2-a]pyrimidines and -pyridines
    Publication number: 20130190332
    Abstract: Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: July 7, 2011
    Publication date: July 25, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Stuart Ince, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer, William Scott
  • BICYCLIC PYRIMIDINES
    Publication number: 20130184273
    Abstract: Compounds of formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: July 11, 2011
    Publication date: July 18, 2013
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Stuart Ince, Hartmut Rehwinkel, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer