Abstract: A filling machine for filling a receptacle with a plurality of items includes a first item drop path having an outlet end, a second item drop path having an outlet end, the second item drop path distinct from the first item drop path and a gating system for selectively accumulating and releasing items. The gating system includes: a single gate mechanism configured for selectively and independently controlling both (i) whether items can exit the outlet end of the first item drop path and (ii) whether items can exit the outlet end of the second item drop path.

Abstract: A filling machine for filling a receptacle with a plurality of items includes a first item drop path having an outlet end, a second item drop path having an outlet end, the second item drop path distinct from the first item drop path and a gating system for selectively accumulating and releasing items. The gating system includes: a single gate mechanism configured for selectively and independently controlling both (i) whether items can exit the outlet end of the first item drop path and (ii) whether items can exit the outlet end of the second item drop path.

Abstract: A novel method for human minor histocompatibility antigen (MiHA) discovery, novel MiHAs identified using this method, as well as uses of the novel MiHAs, are described. One of the features of the novel method is the inclusion of personalized translated transcriptome and/or exome in the database used for peptide identification by mass spectroscopy (MS). Candidate MiHAs are identified by comparing the personalized transcriptome and/or exome to a reference genome and/or to the transcriptome and/or exome of an HLA-matched subject.

Abstract: A threaded connection for drilling or working hydrocarbon wells includes first and second tubular components with an axis of revolution, each including respective male and female ends. At least one of the male or female ends finishes in a terminal surface including a first abutment surface that can come into interfering contact when the connection is made against a second abutment surface provided on a shoulder produced on an opposing tubular component male or female end. At least one of the first and second abutment surfaces is hollowed out by a groove, defining an exterior abutment zone and an interior abutment zone. In the connection made state, the exterior and interior abutment zones are not coplanar, such that contact pressure of the interior abutment zone exerted in a vicinity of the groove is greater than or equal to a minimum value for contact pressure exerted in the exterior abutment zone.

Abstract: A tubular component for a threaded connection includes at one of its ends a threaded zone. The end includes a terminal surface and the threaded zone includes, over at least a portion, threads including, when viewed in a longitudinal section passing through an axis of the tubular component, a thread crest, a thread root, a load flank, and a stabbing flank, such that a respective axial width of thread crests decreases in a direction of the terminal surface while a respective axial width of thread roots increases when considered in the same direction. At least one of a profile of the load flank and a profile of the stabbing flank of a thread portion includes, as a contral portion, a continuous curve provided with a point of inflection such that the profile with the point of inflection in convex at the thread crest and concave close to the thread root.

Abstract: A novel method for human minor histocompatibility antigen (MiHA) discovery, novel MiHAs identified using this method, as well as uses of the novel MiHAs, are described. One of the features of the novel method is the inclusion of personalized translated transcriptome and/or exome in the database used for peptide identification by mass spectroscopy (MS). Candidate MiHAs are identified by comparing the personalized transcriptome and/or exome to a reference genome and/or to the transcriptome and/or exome of an HLA-matched subject.

Abstract: A novel method for human minor histocompatibility antigen (MiHA) discovery, novel MiHAs identified using this method, as well as uses of the novel MiHAs, are described. One of the features of the novel method is the inclusion of personalized translated transcriptome and/or exome in the database used for peptide identification by mass spectroscopy (MS). Candidate MiHAs are identified by comparing the personalized transcriptome and/or exome to a reference genome and/or to the transcriptome and/or exome of an HLA-matched subject.

Abstract: A novel method for human minor histocompatibility antigen (MiHA) discovery, novel MiHAs identified using this method, as well as uses of the novel MiHAs, are described. One of the features of the novel method is the inclusion of personalized translated transcriptome and/or exome in the database used for peptide identification by mass spectroscopy (MS). Candidate MiHAs are identified by comparing the personalized transcriptome and/or exome to a reference genome and/or to the transcriptome and/or exome of an HLA-matched subject.

Abstract: A threaded connection includes first and second tubular components each with an axis of revolution. The first component including a male threaded end, the second component including a female threaded end, and both the male and female threaded ends finishing in a terminal surface. The threaded zones include, over a portion defined as in a self-locking make-up, threads, which before the self-locking make-up and when viewed in a longitudinal section passing through the axis of revolution of the first and second components, each include: a thread crest, a thread root, a load flank, and a stabbing flank. A width of the thread crests of each component reducing in a direction of the terminal surface of the component under consideration, while a width of the thread roots increases. A lead of the male stabbing flanks and/or load flanks is different from a lead of the female stabbing flanks and/or load flanks.

Abstract: An assembly for producing a threaded connection for drilling or working hydrocarbon wells, the connection including first and second tubular components with an axis of revolution, each including respective male and female ends, at least one of the male or female ends finishing in a terminal surface including a first abutment surface that can come into interfering contact when connection is made against a second abutment surface provided on a shoulder produced on the other end, at least one of the first and second abutment surfaces being hollowed out by a groove, thereby defining an exterior abutment zone and an interior abutment zone. In the connection made state, the exterior and interior abutment zones are not coplanar, such that contact pressure of the interior abutment zone exerted in vicinity of the groove is greater than or equal to a minimum value for contact pressure exerted in the exterior abutment zone.

Abstract: A set for manufacturing a threaded connection, including first and second tubular components with an axis of revolution, one of their ends including a threaded zone formed on the external or internal peripheral surface of the component depending on whether the threaded end is of male or female type, the ends finishing in a terminal surface.

Abstract: A threaded tubular connection is provided. The connection includes a male tubular element provided with a male threaded portion and a female tubular element provided with a female threaded portion. The male threaded portion and the female threaded portion each include self-locking threads having a crest, a load flank, a stabbing flank and a root, a load flank lead of the self-locking threads being larger than a stabbing flank lead of the self-locking threads such that in a tightened position of the threaded tubular connection, the load flanks and the stabbing flanks of the male self-locking threads are engaged in tight contact with the load flanks and the stabbing flanks of the female self-locking threads. A transfer zone is axially disposed between the threaded portions and a free end of at least one of the tubular elements, while being axially spaced from the threaded portions.

Abstract: A set for manufacturing a threaded connection, including first and second tubular components with an axis of revolution, one of their ends including a threaded zone formed on the external or internal peripheral surface of the component depending on whether the threaded end is of male or female type, the ends finishing in a terminal surface.

Abstract: A set for producing a threaded connection and a threaded connection. The set includes first and a second tubular components with an axis of revolution, one of their ends including a threaded zone formed on the external or internal peripheral surface of the component depending on whether the threaded end is of male or female type, the ends finishing in a terminal surface orientated radially with respect to the axis of revolution of the tubular components. The threaded zones include threads including, viewed in longitudinal section passing through the axis of revolution of the tubular components, a thread crest, a thread root, a load flank, and a stabbing flank, the width of the thread crests of each tubular component reducing in the direction of the terminal surface of the tubular component under consideration, while the width of the thread roots increases. The lead of the male stabbing flanks and/or load flanks is different from the lead of the female stabbing flanks and/or load flanks.

Abstract: The invention concerns a tubular component for a threaded connection, having at one of its ends (1; 2) a threaded zone (3; 4) formed on its external or internal peripheral surface depending on whether the threaded end is of the male or female type, said end (1; 2) finishing in a terminal surface (7; 8), said threaded zone (3; 4) having, over at least a portion, threads (32; 42) comprising, when viewed in longitudinal section passing through the axis of the tubular component, a thread crest (35), a thread root (36), a load flank (30, 40), a stabbing flank (32, 42), the width of the thread crests (35) reducing in the direction of the terminal surface (7, 8) while the width of the thread roots (36) increases, characterized in that the profile of the load flanks (30; 40) and/or the stabbing flanks (32; 42), viewed in longitudinal section passing through the axis (10) of the tubular component, has as a central portion a continuous curve (34) provided with a point of inflection (I), said profile being convex at the

Abstract: A threaded tubular connection is provided. The connection includes a male tubular element provided with a male threaded portion and a female tubular element provided with a female threaded portion. The male threaded portion and the female threaded portion each include self-locking threads having a crest, a load flank, a stabbing flank and a root, a load flank lead of the self-locking threads being larger than a stabbing flank lead of the self-locking threads such that in a tightened position of the threaded tubular connection, the load flanks and the stabbing flanks of the male self-locking threads are engaged in tight contact with the load flanks and the stabbing flanks of the female self-locking threads. A transfer zone is axially disposed between the threaded portions and a free end of at least one of the tubular elements, while being axially spaced from the threaded portions.