Abstract: A method and apparatus for introducing droplets of liquid sample into an analysis device using a gas stream, the droplets being produced by the application of acoustic energy to a quantity of liquid sample. Acoustic energy may be applied to a quantity of liquid sample located on a solid surface of a sample support so as to eject a droplet of sample from the quantity of sample; the droplet of sample may be entrained in a gas stream; and the droplet of sample may be transported into the analysis device using the gas stream.

Abstract: A method and apparatus for mixing droplets of liquid sample and droplets of a diluent and/or a standard produced by droplet-on-demand generators for use with an analysis device. Two different liquids may be introduced to an analysis device for simultaneous analysis. The method preferably comprises using a first droplet-on-demand generator to provide a first stream of droplets of a first liquid; using a second droplet-on-demand generator to provide a second stream of droplets of a second liquid; and combining the first and second streams of droplets before they enter the analysis device.

Abstract: A method and apparatus for introducing droplets of liquid sample into an analysis device using a gas stream, the droplets being produced by the application of acoustic energy to a quantity of liquid sample. Acoustic energy may be applied to a quantity of liquid sample located on a solid surface of a sample support so as to eject a droplet of sample from the quantity of sample; the droplet of sample may be entrained in a gas stream; and the droplet of sample may be transported into the analysis device using the gas stream.

Abstract: A method and apparatus for mixing droplets of liquid sample and droplets of a diluent and/or a standard produced by droplet-on-demand generators for use with an analysis device. Two different liquids may be introduced to an analysis device for simultaneous analysis.

Abstract: A multichannel optical amplifier having an adjustable gain set point is controlled to permit substantially constant gain tilt control during a gain set-point change so that the channel powers are maintained during system modification. To this end the amplifier comprises an erbium doped fibre (EDF) loop and associated pump amplifier for amplifying an optical signal comprising channels of different wavelengths, a variable optical attenuator (VOA) for controlling the gain of the amplifier by applying a loss profile that varies with wavelength so that the different channels are amplified in accordance with a required gain tilt, preferably a zero gain tilt, and a PI controller for applying a gain tilt adaptation profile to compensate for an inherent gain tilt to produce the required gain tilt.