Patents by Inventor Olli CARPEN

Olli CARPEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for selecting patients for treatment with an EGFR inhibitor
    Patent number: 8609354
    Abstract: The present invention relates to cancer diagnostics and therapies and to the detection of alterations in cancer cells that are diagnostic, prognostic or predictive. In particular, the present invention provides a method for detecting and analyzing whether a patient suffering from a cancer is responsive to the treatment with an EGFR inhibitor. In the method, a tissue section from a cancer sample is subjected to assays based on immunohistochemistry and enzymatic metallography.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: December 17, 2013
    Assignees: Hospital District of Southwest Finland
    Inventors: Olli Carpén, Minnamaija Lintunen, Raija Ristamäki, Jari Sundström, Annika Ålgars
  • METHOD FOR SELECTING PATIENTS FOR TREATMENT WITH AN EGFR INHIBITOR
    Publication number: 20110217296
    Abstract: The present invention relates to cancer diagnostics and therapies and to the detection of alterations in cancer cells that are diagnostic, prognostic or predictive. In particular, the present invention provides a method for detecting and analyzing whether a patient suffering from a cancer is responsive to the treatment with an EGFR inhibitor. In the method, a tissue section from a cancer sample is subjected to assays based on immunohistochemistry and enzymatic metallography.
    Type: Application
    Filed: March 3, 2011
    Publication date: September 8, 2011
    Applicant: HOSPITAL DISTRICT OF SOUTHWEST FINLAND
    Inventors: Olli CARPEN, Minnamaija LINTUNEN, Raija RISTAMAKI, Jari SUNDSTROM, Annika ALGARS
  • Myotilin, a novel actin-organizing protein
    Patent number: 6458929
    Abstract: The present invention concerns a novel cytoskeletal protein, myotilin, which contains Ig-like domains homologous to a giant sarcomeric structural protein titin. Myotilin is expressed in skeletal and cardiac muscles, it colocalizes with &agr;-actinin in the sarcomeric I-bands and directly interacts with &agr;-actinin. Expression of myotilin in mammalian non-muscle cells and in yeast causes reorganization of actin into thick F-actin bundles and inhibits growth of yeast cells.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: October 1, 2002
    Assignee: Licentia Ltd.
    Inventors: Olli Carpén, Mikaela Grönholm, Leena Heiska, Olli-Matti Mykkänen, Paula Salmikangas