Patents by Inventor Olli Teronen

Olli Teronen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of inhibiting membrane-type matrix metalloproteinase
    Publication number: 20020045603
    Abstract: The invention is a method of inhibiting the activity of membrane-type matrix metalloproteinase (MT-MMP) in biological systems. Accordingly, the invention permits the treatment of medical conditions in mammals that are characterized by MT-MMP activity, and especially those conditions characterized by excessive MT-MMP activity. The method employs a tetracycline compound, preferably a non-antimicrobial tetracycline, and more preferably 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3) or 6-&agr;-deoxy-5-hydroxy-4-de(dimethylamino)tetracycline (CMT-8) to inhibit the MT-MMP activity.
    Type: Application
    Filed: May 14, 2001
    Publication date: April 18, 2002
    Applicant: The Research Foundation of State University of New York
    Inventors: Lorne M. Golub, Hsi-Ming Lee, Timo Sorsa, Olli Teronen, Tuula Salo
  • Diagnostic method for detection of periodontitis or peri-implantitis
    Patent number: 6280687
    Abstract: The invention relates to methods and test kits for diagnosis of periodontal disease activity in mammals, especially in human. The methods of the invention provide for rapid chair-side diagnosis of periodontitis, peri-implantitis and HIV (+)-infection/AIDS-disease related periodontal diseases. Especially, the methods of the invention provide for rapid chair-side diagnosis of the loss of bone density associated with periodontal diseases.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: August 28, 2001
    Assignees: The Research Foundation of State University of NY, Medix Biochemica
    Inventors: Lorne M. Golub, Timo Sorsa, Olli Teronen, Sari Hannele Tikanoja
  • Method of inhibiting membrane-type matrix metalloproteinase
    Patent number: 6277061
    Abstract: The invention is a method of inhibiting the activity of membrane-type matrix metalloproteinase (MT-MMP) in biological systems. Accordingly, the invention permits the treatment of medical conditions in mammals that are characterized by MT-MMP activity, and especially those conditions characterized by excessive MT-MMP activity. The method employs a tetracycline compound, preferably a non-antimicrobial tetracycline, and more preferably 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3) or 6-&agr;-deoxy-5-hydroxy-4-de(dimethylamino)tetracycline (CMT-8) to inhibit the MT-MMP activity.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: August 21, 2001
    Assignee: The Research Foundation of State University of New York
    Inventors: Lorne M. Golub, Hsi-Ming Lee, Timo Sorsa, Olli Teronen, Tuula Salo
  • Diagnostic method for detection of periodontitis or peri-implantitis
    Patent number: 6143506
    Abstract: The invention relates to methods and test kits for diagnosis of periodontal disease activity in mammals, especially in human. The methods of the invention provide for rapid chair-side diagnosis of periodontitis, peri-implantitis and HIV (+)-infection/AIDS-disease related periodontal diseases. Especially, the methods of the invention provide for rapid chair-side diagnosis of the loss of bone density associated with periodontal diseases.
    Type: Grant
    Filed: August 13, 1998
    Date of Patent: November 7, 2000
    Assignee: The Research Foundation of State of NY
    Inventors: Lorne M. Golub, Timo Sorsa, Olli Teronen, Sari Hannele Tikanoja