Patents by Inventor Olov Holmovist

Olov Holmovist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of a blood platelet lysate for use in a cell culture medium for hybridoma cells
    Patent number: 5198357
    Abstract: A platelet lysate is produced from plasma derived from animal whole blood that contains an added citrate to prevent coagulation of the blood during storage. The lysate is prepared by centrifuging plasma to produce a platelet rich paste, adding calcium to the paste to lyse the platelets therein and coagulate fibrinogen to produce a clear liquid containing lysed platelets, sterile filtering the liquid and collecting a liquid filtrate containing the lysed platelets. The obtained lysate of platelets can be used to wholly or partly replace foetal calf serum in cell culture, such as in culture of hybridoma cells for preparing monoclonal antibodies.
    Type: Grant
    Filed: December 26, 1990
    Date of Patent: March 30, 1993
    Assignee: Ellco Food AB
    Inventors: Olov Holmovist, Bengt Westermark