Abstract: A crosslinked CCN/CMC microsphere comprising a stably incorporated radionuclide. The microsphere can be prepared by droplet microfluidics and used in a method for radiation treatment comprising the administration of microspheres with incorporated radionuclide.

Abstract: The present disclosure describes a plurality of microspheres that include carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). The microspheres are biocompatible, bioresorbable, and biodegradable. The microspheres may be used in personal care products, such as, for example, toothpaste, topical pain relief products, topical antibiotic products, skincare products such as anti-wrinkle products, eczema products, skin scrubs, acne cleansers, exfoliators, body washes, soaps, pre-shave creams, or the like.

Abstract: Radio frequency (RF) energy is transmitted through the application of a RF signal to an external RF energy interface, where the RF signal oscillates at a frequency in an energy transmission band. The transmitted RF energy is received at an implanted medical device, and energy derived from the received RF energy is stored in a direct current (DC) energy storage component of the device. A therapeutic output signal is generated from the stored energy and delivered by the implantable medical device to a patient through one or more electrodes. The therapeutic output signal is configurable to provide either one of RF stimulation therapy and RF ablation therapy, and comprises pulses of an RF signal oscillating at a frequency in a therapy band that is greater than the energy transmission band.

Abstract: Radio frequency (RF) energy is transmitted through the application of a RF signal to an external RF energy interface, where the RF signal oscillates at a frequency in an energy transmission band. The transmitted RF energy is received at an implanted medical device, and energy derived from the received RF energy is stored in a direct current (DC) energy storage component of the device. A therapeutic output signal is generated from the stored energy and delivered by the implantable medical device to a patient through one or more electrodes. The therapeutic output signal is configurable to provide either one of RF stimulation therapy and RF ablation therapy, and comprises pulses of an RF signal oscillating at a frequency in a therapy band that is greater than the energy transmission band.

Abstract: An active implantable medical device configured for chronic implant in a patient includes a housing. At least one of a radio frequency (RF) module configured to generate a therapeutic output signal in a form of a pulsed a RF signal, and deliver the signal to neural tissue of the patient, and a health information module configured to collect information directed to a mechanical integrity of an orthopedic implant device and an activity of the patient, is located within the housing. The housing is configured to be associated with an orthopedic implanted device through attachment to a piece of implant hardware, or engagement with a passageway through the orthopedic implanted device. Alternatively, an active implantable medical device is incorporated and integrated into a component of an orthopedic implanted device.

Abstract: Radio frequency (RF) energy is transmitted through the application of a RF signal to an external RF energy interface, where the RF signal oscillates at a frequency in an energy transmission band. The transmitted RF energy is received at an implanted medical device, and energy derived from the received RF energy is stored in a direct current (DC) energy storage component of the device. A therapeutic output signal is generated from the stored energy and delivered by the implantable medical device to a patient through one or more electrodes. The therapeutic output signal is configurable to provide either one of RF stimulation therapy and RF ablation therapy, and comprises pulses of an RF signal oscillating at a frequency in a therapy band that is greater than the energy transmission band.

Abstract: The present disclosure describes a plurality of microspheres that include carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). The microspheres are biocompatible, bioresorbable, and biodegradable. The microspheres may be used in personal care products, such as, for example, toothpaste, topical pain relief products, topical antibiotic products, skincare products such as anti-wrinkle products, eczema products, skin scrubs, acne cleansers, exfoliators, body washes, soaps, pre-shave creams, or the like.

Abstract: A crosslinked NATURAL POLYMER POLYMER/NATURAL POLYMER POLYMER microsphere comprising a stably incorporated radionuclide. The microsphere can be prepared by droplet microfluidics and used in a method for radiation treatment comprising the administration of microspheres with incorporated radionuclide.

Abstract: The automated posture correction system comprises a spinal brace and an electronic device. The spinal brace configured to be worn by the user comprises inflatable elements and at least one actuator. The inflatable elements, positioned along the length of the predetermined sections of the spinal area of the user, comprise sensors for detecting one or more parameters of the spinal area. The electronic device receives sensor data variables generated by the sensors based on the detected parameters via a communications network. The electronic device compares the parameters with a set of preset reference values stored in memory unit. The electronic device actuates the actuator to inflate or deflate the inflatable elements based on the sensor data variables differing from the set of preset reference values. The inflatable elements selectively apply force on the predetermined sections of the spinal area for dynamically improving the posture of the user.

Abstract: A system for providing a drug-eluting resorbable hydrogel for treating chronic pain, the system including carboxymethyl chitosan and oxidized carboxymethyl cellulose solutions, which together with one or more bioactive agents, can be mixed and delivered at the time of use in order to gel in situ within a joint space. Once delivered, the hydrogel can provide bioactive agents such as NSAIDs directly to the areas commonly associated with chronic pain, including to the spine, knee, shoulder, and elbow. The hydrogel is substantially non-inflammatory, and substantially biodegradable over time, to provide prolonged drug release.