Patents by Inventor Orhan Soykan
Orhan Soykan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150149096Abstract: A device, system and related methods for monitoring a mammal with heart failure, kidney disease or both, to make predictions about the likelihood of a life threatening ventricular arrhythmia. The device, system and related methods can have one or more sensors in electronic communication with a processor, the sensors determining one or more physiological parameters of a patient, and communicating the physiological parameter to the processor, and the processors using an algorithm to determine the probability of a ventricular arrhythmia based on the physiological parameters.Type: ApplicationFiled: November 26, 2014Publication date: May 28, 2015Applicant: Medtronic, Inc.Inventor: Orhan Soykan
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Publication number: 20150148697Abstract: A system and method for synchronizing patient medical parameters and dialysis parameters. The system and related method allow for the determination of the effect of dialysis on patient health. The invention also allows for the determination of whether observed patient health effects are due to specific dialysis parameters and for making necessary changes to the dialysis parameters in order to improve patient health.Type: ApplicationFiled: November 26, 2014Publication date: May 28, 2015Applicant: MEDTRONIC, INC.Inventors: John BURNES, VenKatesh MANDA, Tico BLUMENTHAL, Orhan Soykan
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Publication number: 20150134262Abstract: A method of genetic testing utilizing a system of servers, databases, computers, software applications, or any other computing module. The computing modules allow for creation of a genetic test script and the analysis of genetic information based on the genetic test script. The system can also account for the use of proprietary biomarkers.Type: ApplicationFiled: September 11, 2014Publication date: May 14, 2015Applicant: YouGene Corp.Inventors: Ryan Downs, Ferdinand Los, Orhan Soykan, Roger C. Hahn
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Publication number: 20150127378Abstract: Disclosed are systems and methods for facilitating licensing of intellectual property rights and transfer of payments between intellectual property rights holders and users or licensees while shielding patient privacy. Information contained in a patient records database is restricted such that one or more fields of information are not available to one or more users of a privacy facilitating system. The patient records database containing patient records including patient identification information and diagnostic information is accessed along with a proprietary records database containing records of proprietary biomarkers and intellectual property rights holders of the proprietary biomarkers. The patient records database and the proprietary records database are queried to determine the presence of a proprietary biomarker in a patient record.Type: ApplicationFiled: October 10, 2014Publication date: May 7, 2015Applicant: YouGene Corp.Inventors: Ryan Downs, Ferdinand Los, Orhan Soykan, Roger C. Hahn
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Publication number: 20150032023Abstract: In general, the invention is directed to methods and devices for determining an ion concentration in the extracellular fluid of a patient. As examples, the ion may be one or more of potassium, sodium, chloride, or calcium. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of ions in the extracellular fluid as a function of the response. The system may detect an ion imbalance based upon the determined concentration of ions.Type: ApplicationFiled: October 15, 2014Publication date: January 29, 2015Applicant: MEDTRONIC, INC.Inventors: Orhan Soykan, Timothy H. Robinson, James K. Carney, Tara L. Nahey, Cygni Chan
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Patent number: 8940522Abstract: Activation of an enzyme in a bodily fluid is detected based on the amount of cleavage of a substrate for the enzyme. The substrate is tagged with two fluorescent dyes—a donor and an acceptor. The tagged substrate is presented to the bodily fluid. A device emits energy at a first wavelength into the bodily fluid, and detects energy at second and third wavelengths emitted by the dyes in response to the energy at the first wavelength. Prior to enzymatic cleavage of the substrate, the acceptor emits energy at the third wavelength in response to energy at the second wavelength received through fluorescent resonant energy transfer (FRET) from the donor. After enzymatic cleavage of the substrate, the donor emits energy at the second wavelength. The device can determine the concentration of activated enzyme within the bodily fluid based on the relative intensities of energy at the second and third wavelengths.Type: GrantFiled: August 22, 2011Date of Patent: January 27, 2015Assignee: Medtronic, Inc.Inventors: Orhan Soykan, Maura G. Donovan, Amy E. Thompson
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Patent number: 8903492Abstract: In general, the invention is directed to methods and devices for determining an ion concentration in the extracellular fluid of a patient. As examples, the ion may be one or more of potassium, sodium, chloride, or calcium. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of ions in the extracellular fluid as a function of the response. The system may detect an ion imbalance based upon the determined concentration of ions.Type: GrantFiled: February 7, 2006Date of Patent: December 2, 2014Assignee: Medtronic, Inc.Inventors: Orhan Soykan, Timothy H. Robinson, James K. Carney, Tara L. Nahey, Cygni Chan
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Publication number: 20140148754Abstract: The invention relates to a method and device for dialysis and or bulk fluid removal by generating a fibrosis chamber within a body cavity and performing dialysis or bulk fluid removal. An implantable medical device is described having a fibrosis chamber and a pump. A dialysis chamber and an optional electrodialysis unit can further be provided. An additional controller uses sensory feedback to regulate the fluid levels by altering the extracellular fluid retention within the fibrosis chamber. This device can be used for the treatment of patients with chronic kidney disease who may also be suffering from cardiorenal syndrome and hypertension.Type: ApplicationFiled: February 1, 2014Publication date: May 29, 2014Applicant: MEDTRONIC, INC.Inventors: Orhan Soykan, Carl Schu, Kimberly A. Chaffin
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Publication number: 20140088442Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.Type: ApplicationFiled: March 15, 2013Publication date: March 27, 2014Applicant: Medtronic, Inc.Inventors: Orhan Soykan, VenKatesh R. Manda, Martin T. Gerber, Christopher M. Hobot, Linda L. Ruetz, Carl Schu
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Patent number: 8641659Abstract: The invention relates to a method and device for dialysis and or bulk fluid removal by generating a fibrosis chamber within a body cavity and performing dialysis or bulk fluid removal. An implantable medical device is described having a fibrosis chamber and a pump. A dialysis chamber and an optional electrodialysis unit can further be provided. An additional controller uses sensory feedback to regulate the fluid levels by altering the extracellular fluid retention within the fibrosis chamber. This device can be used for the treatment of patients with chronic kidney disease who may also be suffering from cardiorenal syndrome and hypertension.Type: GrantFiled: February 17, 2012Date of Patent: February 4, 2014Assignee: Medtronic, Inc.Inventors: Orhan Soykan, Carl Schu, Kimberly Chaffin
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Publication number: 20130274642Abstract: A dialysis device for operation in multiple modes and for maintaining a known gradient of potassium ion or other electrolyte between the blood of a patient and a dialysate fluid is described. The dialysis device is capable of being used for hemodialysis or peritoneal dialysis, and the dialysis device is capable of operation with a dialysate purification unit outside of a clinical setting or with a supply of water that can be supplied in a clinical setting. The dialysis device has a composition sensor containing a potassium-sensitive electrode for measuring a potassium ion concentration in one or more of the patient's blood and the dialysate fluid and an infusate pump operated to adjust a potassium ion concentration in the dialysate fluid based at least in part on data from the composition sensor.Type: ApplicationFiled: March 15, 2013Publication date: October 17, 2013Inventors: Orhan Soykan, Bryant J. Pudil, Thomas E. Meyer, Linda L. Ruetz, Carl Schu
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Patent number: 8335652Abstract: A self-improving identification method classifies specimens based on class identifiers. The system stores specimen profiles in a database that is updated with additional specimen profiles and with follow-up data that corrects classification of specimens that were initially incorrectly classified. Algorithms use the updated database to discover new class identifiers, modify thresholds of known class identifiers, and drop unnecessary class identifiers to improve classification of specimens.Type: GrantFiled: June 21, 2005Date of Patent: December 18, 2012Assignee: Yougene Corp.Inventors: Orhan Soykan, Daisy Phan Cross
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Publication number: 20120309641Abstract: Variations in certain genomic sequences useful as genetic markers of Sudden Cardiac Death (“SCD”), or Sudden Cardiac Arrest (“SCA”) risk, are described. Novel diagnostic kits and methods employing these genetic markers are used in assessing the risk of SCD, or SCA. Methods of distinguishing patients having an increased susceptibility to SCD, or SCA, through use of these markers, alone or in combination with other markers, are also provided. Further, methods for assessing the need for an Implantable Cardio Defibrillator (“ICD”) in a patient with computer programmable processors and genetic databases are described.Type: ApplicationFiled: October 19, 2011Publication date: December 6, 2012Applicant: MEDTRONIC, INC.Inventors: Orhan Soykan, Tara Nahey, Jeffrey Lande
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Publication number: 20120277546Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.Type: ApplicationFiled: April 19, 2012Publication date: November 1, 2012Applicant: MEDTRONIC, INC.Inventors: Orhan Soykan, VenKatesh R. Manda, Martin T. Gerber, Christopher M. Hobot
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Publication number: 20120277619Abstract: In some examples, the disclosure relates to a systems, devices, and techniques for monitoring the occurrence of food intake by a patient. In one example, the disclosure relates to a method including determining a phase of tissue impedance at one or more gastrointestinal tract locations of a patient via a medical device, and determining the occurrence of food intake by the patient based on the determined phase of the tissue impedance. In some examples, a medical device may control the delivery of therapy to a patient based on the determination of food intake based on the phase to the tissue impedance.Type: ApplicationFiled: January 27, 2012Publication date: November 1, 2012Applicant: Medtronic, Inc.Inventors: Warren L. Starkebaum, Orhan Soykan, Daniel Bloomberg
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Publication number: 20120220926Abstract: The invention relates to a method and device for dialysis and or bulk fluid removal by generating a fibrosis chamber within a body cavity and performing dialysis or bulk fluid removal. An implantable medical device is described having a fibrosis chamber and a pump. A dialysis chamber and an optional electrodialysis unit can further be provided. An additional controller uses sensory feedback to regulate the fluid levels by altering the extracellular fluid retention within the fibrosis chamber. This device can be used for the treatment of patients with chronic kidney disease who may also be suffering from cardiorenal syndrome and hypertension.Type: ApplicationFiled: February 17, 2012Publication date: August 30, 2012Applicant: MEDTRONIC, INC.Inventors: Orhan Soykan, Carl Schu, Kimberly A. Chaffin
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Publication number: 20120059778Abstract: A self-improving classification system classifies specimens based on class identifiers. The system stores specimen profiles in a database that is updated with additional specimen profiles and with follow-up data that corrects classification of specimens that were initially incorrectly classified. Algorithms use the updated database to discover new class identifiers, modify thresholds of known class identifiers, and drop unnecessary class identifiers to improve classification of specimens.Type: ApplicationFiled: August 22, 2011Publication date: March 8, 2012Applicant: MEDTRONIC, INC.Inventors: Orhan Soykan, Daisy Phan Cross
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Publication number: 20120046642Abstract: Activation of an enzyme in a bodily fluid is detected based on the amount of cleavage of a substrate for the enzyme. The substrate is tagged with two fluorescent dyes—a donor and an acceptor. The tagged substrate is presented to the bodily fluid. A device emits energy at a first wavelength into the bodily fluid, and detects energy at second and third wavelengths emitted by the dyes in response to the energy at the first wavelength. Prior to enzymatic cleavage of the substrate, the acceptor emits energy at the third wavelength in response to energy at the second wavelength received through fluorescent resonant energy transfer (FRET) from the donor. After enzymatic cleavage of the substrate, the donor emits energy at the second wavelength. The device can determine the concentration of activated enzyme within the bodily fluid based on the relative intensities of energy at the second and third wavelengths.Type: ApplicationFiled: August 22, 2011Publication date: February 23, 2012Applicant: Medtronic, Inc.Inventors: Orhan Soykan, Maura G. Donovan, Amy E. Thompson
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Patent number: 8057466Abstract: A method and device are described to form a sensor using a cardiomyocyte by advancing a catheter into the tissue of interest, cardiac in the preferred embodiment, and using the catheter to ablate a cone- or a dome-shaped region to form an electrically isolated section of tissue. An electrode is later fixed to the region encompassed by the dome-shaped area of tissue and used to detect the electrophysiological activity of this electrically independent cluster of cells. These cells combined with the electrode and a detection circuitry will form a cell-based sensor to monitor the effects of the anti-arrhythmic drugs in the circulation. The inventive device includes an ablation catheter and a sensing lead. Catheter is a hollow conductor which used to carry RF power from the external generator to the myocardium and to form a cone-shaped ablation zone to electrically isolate a part of myocardium from the rest.Type: GrantFiled: September 5, 2006Date of Patent: November 15, 2011Assignee: Medtronic, Inc.Inventor: Orhan Soykan
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Patent number: 8027791Abstract: A self-improving classification system classifies specimens based on class identifiers. The system stores specimen profiles in a database that is updated with additional specimen profiles and with follow-up data that corrects classification of specimens that were initially incorrectly classified. Algorithms use the updated database to discover new class identifiers, modify thresholds of known class identifiers, and drop unnecessary class identifiers to improve classification of specimens.Type: GrantFiled: June 21, 2005Date of Patent: September 27, 2011Assignee: Medtronic, Inc.Inventor: Orhan Soykan