Abstract: The present invention is directed to a method for determining the suitability of a subject to TNF? inhibitor therapy. Further provide is a method for treating a subject afflicted with a TNF? related disease.

Abstract: Optical connector assemblies and optical cable assemblies incorporating a supplemental input voltage are disclosed. In one embodiment, an optical connector assembly includes housing and an electrical connector at a face of the housing. The electrical connector includes an input voltage contact for receiving an input voltage. The optical connector assembly further includes voltage converter operable to convert the input voltage to an output voltage at a converter output, a voltage clamping device electrically coupled to the converter output, and a supplemental voltage conductor. The output voltage is greater than the input voltage. The supplemental voltage conductor is electrically coupled to an output of the voltage clamping device and provides a supplemental output voltage at an output of the voltage clamping device. The optical connector assembly further includes an active optical circuit that converts electrical data signals into optical signals.