Abstract: Systems for calculating extent of congestive heart failure (CHF) and/or identifying exacerbation of CHF. In one embodiment, a system includes smartglasses configured to be worn on a user's head, and an inward-facing camera and a sensor, both physically coupled to the smartglasses. The inward-facing camera is mounted more than 5 mm away from the head and captures images of an area comprising skin on the user's head, which is larger than 4 cm{circumflex over (?)}2. The sensor measures a signal indicative of a respiration rate of the user (respiration signal). The system also includes a computer that calculates the extent of CHF based on: a facial blood flow pattern recognizable in the images, and respiration rate recognizable in the respiration signal.

Abstract: Described herein are embodiments of systems and a method to identify orthostatic hypotension and postural-orthostatic tachycardia syndrome. One system includes a head-mounted device configured to measure photoplethysmographic signal (PPG signal) at a region on a user's head, and a head-mounted camera configured to capture images indicative of the user's posture. Additionally, the system includes a computer that calculates systolic and diastolic blood pressure values based on the PPG signal, and identifies orthostatic hypotension based on a drop of systolic blood pressure below a first threshold, and/or a drop of diastolic blood pressure below a second threshold, within a predetermined duration from a transition in the posture from supine to sitting posture, or from sitting to standing posture.

Abstract: System and Method to detect an abnormal medical event based on an asymmetrical change to blood flow. The system includes right-side and left-side head-mounted devices to measure signals indicative of photoplethysmographic signals (PPG signals) on the right and left sides of a user's head, and a computer that detects the abnormal medical event based on an asymmetrical change to blood flow recognizable in the PPG signals. Optionally, the asymmetrical change to the blood flow corresponds to a deviation of the PPG signals compared to a baseline that is based on previous measurements of PPG signals of the user, taken before the abnormal medical event.

Abstract: Disclosed herein are systems and methods for detecting a physiological response using different types of photoplethysmography sensors. Examples of physiological responses that may be detected include an allergic reaction, a stroke, a migraine, stress, certain emotional responses, manifestation of pain, and blood pressure. In one embodiment, a head-mounted contact photoplethysmography device measures a signal indicative of photoplethysmogram signal at a first region that includes exposed skin on a user's head (PPG signal). A camera, located more than 10 mm away from the user's head, captures images of a second region that includes exposed skin on the user's head. A computer detects the physiological response based on: (i) imaging photoplethysmogram signals (iPPG signals) recognizable in the images, and (ii) correlations between the PPG signal and the iPPG signals.

Abstract: Systems and methods for detecting an occurrence of a transient ischemic attack (TIA). In one embodiment, a device is utilized to measure first and second signals indicative of photoplethysmogram signals at first and second regions on the left and right sides of a user's head (PPGSL and PPGSR, respectively). A computer detects the occurrence of a TIA based on PPGSL and PPGSR that exhibit a pattern that involves the following: (i) an asymmetry between PPGSL and PPGSR, which is below a threshold, during a first period spanning more than a day; (ii) an asymmetry between PPGSL and PPGSR, which exceeds the threshold, during a second period following the first period and spanning between 5 and 180 minutes; and (iii) an asymmetry between PPGSL and PPGSR, which falls below the threshold, during a third period following the second period.

Abstract: Described herein are embodiments of a system and a method to calculate a user's physiological signal, such as blood pressure, cardiac output, or tissue perfusion. The system includes a head-mounted device configured to measure photoplethysmographic signal (PPG signal) at a region on the user's head, and a head-mounted camera configured to capture images indicative of the user's posture. Additionally, the system includes a computer configured to calculate the physiological signal based on the PPG signal and the user's posture. In some embodiments, the computer adjusts calculations of the physiological signal based on the user's posture, such that for the same PPG signal the computer outputs different values for the physiological signal for the following different postures: standing, sitting, and lying down.

Abstract: A system for detecting blood pressure based on imaging photoplethysmography (iPPG) includes a first inward-facing head-mounted camera to capture images of a first region of interest located on the face below the eyes and above the lips (IMROI1) of a user, and a second inward-facing head-mounted camera to capture images of a second region of interest comprising a portion of a temple and/or forehead (IMROI2) of the user. The system further includes a computer to calculate a blood pressure value for the user based on first and second photoplethysmographic signals recognizable in IMROI1 and IMROI2.

Abstract: A system for detecting blood pressure based on imaging photoplethysmography (iPPG) includes an inward-facing head-mounted camera to capture images of a first region of interest (IMROI1) that comprises a portion of exposed skin of the user's face, and an outward-facing head-mounted camera to capture images of a second region of interest (IMROI2) that comprises exposed skin on a hand of the user. The head-mounted cameras may be coupled to a frame of eyeglasses or smartglasses, and the system further includes a computer to calculate a blood pressure value for the user based on first and second photoplethysmographic signals recognizable in IMROI1 and IMROI2.

Abstract: A system for detecting blood pressure based on imaging photoplethysmography (iPPG) includes a first inward-facing head-mounted camera to capture images of a first region of interest located on the face below the eyes and above the lips (IMROI1) of a user, and a second inward-facing head-mounted camera to capture images of a second region of interest comprising a portion of a temple and/or forehead (IMROI2) of the user. The system further includes a computer to calculate a blood pressure value for the user based on first and second photoplethysmographic signals recognizable in IMROI1 and IMROI2.

Abstract: A system for detecting blood pressure based on imaging photoplethysmography (iPPG) includes an inward-facing head-mounted camera to capture images of a first region of interest (IMROI1) that comprises a portion of exposed skin of the user's face, and an outward-facing head-mounted camera to capture images of a second region of interest (IMROI2) that comprises exposed skin on a hand of the user. The head-mounted cameras may be coupled to a frame of eyeglasses or smartglasses, and the system further includes a computer to calculate a blood pressure value for the user based on first and second photoplethysmographic signals recognizable in IMROI1 and IMROI2.