Patents by Inventor Orit Kollet

Orit Kollet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stem cells having increased sensitivity to SDF-1 and methods of generating and using same
    Patent number: 8252588
    Abstract: The present invention relates to stem cells which exhibit increased sensitivity to a chemoattractant and, more particularly, to methods of generating and using them such as in clinical applications involving stem cell transplantation.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: August 28, 2012
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Orit Kollet, Tsvee Lapidot
  • Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
    Patent number: 8029780
    Abstract: The present invention relates to stem cells which exhibit increased sensitivity to a chemoattractant and, more particularly, to methods of generating and using them such as in clinical applications involving stem cell transplantation.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: October 4, 2011
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Orit Kollet, Tsvee Lapidot
  • Use of Protease or a Protease Inhibitor for the Manufacture of Medicaments
    Publication number: 20080305097
    Abstract: The invention relates to the use of a cathepsin K inhibitor (CTKI) or CTK, a mutein, isoform, fused protein, functional derivative, active fraction, circularly permutated derivative, a salt or inducer thereof in the manufacture of a medicament for treating a disease in which SDF-1 activity and/or concentration is involved with the development and/or course of the disease.
    Type: Application
    Filed: October 27, 2005
    Publication date: December 11, 2008
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Tsvee Lapidot, Orit Kollet
  • MIGRATION OF HEMATOPOIETIC STEM CELLS AND PROGENITOR CELLS TO THE LIVER
    Publication number: 20080193426
    Abstract: The invention relates to transplantation of hematopoietic stem cells (HSC) and/or progenitor cells (HPC) into the liver. More specifically the invention relates to the use of chemokines, preferably SDF-1, for enhancing homing of HSC/HPC to the liver.
    Type: Application
    Filed: November 30, 2007
    Publication date: August 14, 2008
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Orit KOLLET, Tsvee Lapidot
  • Nucleic acids encoding chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
    Patent number: 7374912
    Abstract: Chimeric proteins constructed from the fusion of the naturally occurring form of the soluble IL-6 receptor and IL-6 which are useful for treatment of cancer and liver disorders, enhancement of bone marrow transplantation, and treatment of other IL-6 related conditions are provided.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: May 20, 2008
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Michel Revel, Judith Chebath, Tsvee Lapidot, Orit Kollet
  • Chimeric Interleukin-6 Soluble Receptor/Ligand Protein, Analogs Thereof and Uses Thereof
    Publication number: 20070172455
    Abstract: Chimeric proteins constructed from the fusion of the naturally occurring form of the soluble IL-6 receptor and IL-6 which are useful for treatment of cancer and liver disorders, enhancement of bone marrow transplantation, and treatment of other IL-6 related conditions are provided.
    Type: Application
    Filed: March 20, 2007
    Publication date: July 26, 2007
    Applicant: Yeda Research and Development Co., Ltd.
    Inventors: Michel Revel, Judith Chebath, Tsvee Lapidot, Orit Kollet
  • Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
    Publication number: 20070172464
    Abstract: The present invention relates to stem cells which exhibit increased sensitivity to a chemoattractant and, more particularly, to methods of generating and using them such as in clinical applications involving stem cell transplantation.
    Type: Application
    Filed: April 7, 2004
    Publication date: July 26, 2007
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Orit Kollet, Tsvee Lapidot
  • Chimeric interleukin-6 soluble receptor/ligand proteins
    Patent number: 7198781
    Abstract: Chimeric proteins constructed from the fusion of the naturally occurring form of the soluble IL-6 receptor and IL-6 which are useful for treatment of cancer and liver disorders, enhancement of bone marrow transplantation, and treatment of other IL-6 related conditions are provided.
    Type: Grant
    Filed: July 9, 1998
    Date of Patent: April 3, 2007
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Michel Revel, Judith Chebath, Tsvee Lapidot, Orit Kollet
  • Stem cells having increased sensitivity to sdf-1 and methods of generating and using same
    Publication number: 20070003540
    Abstract: The present invention relates to stem cells which exhibit increased sensitivity to a chemoattractant and, more particularly, to methods of generating and using them such as in clinical applications involving stem cell transplantation.
    Type: Application
    Filed: April 7, 2004
    Publication date: January 4, 2007
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Orit Kollet, Tsvee Lapidot
  • Migration of hematopoietic stem cells and progenitor cells to the liver
    Publication number: 20060251616
    Abstract: The invention relates to transplantation of hematopoietic stem cells (HSC) and/or progenitor cells (HPC) into the liver. More specifically the invention relates to the use of chemokines, preferably SDF-1, for enhancing homing of HSC/HPC to the liver.
    Type: Application
    Filed: July 12, 2006
    Publication date: November 9, 2006
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Orit Kollet, Tsvee Lapidot
  • Migration of hematopoietic stem cells and progenitor cells to the liver
    Publication number: 20050152871
    Abstract: The invention relates to transplantation of hematopoietic stem cells (HSC) and/or progenitor cells (HPC) into the liver. More specifically the invention relates to the use of chemokines, preferably SDF-1, for enhancing homing of HSC/HPC to the liver.
    Type: Application
    Filed: December 5, 2002
    Publication date: July 14, 2005
    Inventor: Orit Kollet