Patents by Inventor Osamu Hiroshima

Osamu Hiroshima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Network data generator, network data generation method, and program
    Patent number: 11913804
    Abstract: Appropriate network data for an indoor map can be efficiently generated using input data including a structure of an indoor space. In a network data generation device (10) that generates, from the input data including at least the structure of the indoor space and information indicating a property based on the structure of the indoor space, network data, the network data including a link representing a movable space on a map and a node that is a starting point or an ending point of the link, a link/node generation unit (142) generates a set of links and a set of nodes based on the input data.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: February 27, 2024
    Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Mitsuru Mochizuki, Nobuaki Hiroshima, Osamu Matsuda, Hitoshi Seshimo
  • Biphenylmethane derivative and pharmacological use
    Patent number: 5506238
    Abstract: The biphenylmethane derivative having the formula (I) is useful to prevent and treat hypertension and cardiac failure. ##STR1## in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, --S--R7, --SO2--R7, --C.tbd.C--R7 or --(CH2)p--OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, --A1=A2--A3=A4-- is --CH=CH--CH=CH--, --N=CH--CH=CH--, --CH=N--CH=CH--, --CH=CH--N=CH--, --CH=CH--CH=N-- or --CH=N--CH=N--, R2 and R3 are each hydrogen, a halogen, a lower alkyl, a lower alkoxy, a carbamoyl or cyano, R4 is hydrogen or a lower alkyl, R5 is 1H-tetrazol-5-yl, carboxyl (--COOH) or a carboxylic ester and R6 is hydrogen, a halogen, hydroxyl or a lower alkoxy, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: May 1, 1992
    Date of Patent: April 9, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Kazutoshi Miyake, Masayuki Matsukura, Naoki Yoneda, Osamu Hiroshima, Nobuyuki Mori, Hiroki Ishihara, Takashi Musha, Toshiyuki Matsuoka, Sachiyuki Hamano, Norio Minami
  • Biphenylmethane derivative and pharmacological use
    Patent number: 5328911
    Abstract: The biphenylmethane derivative having the formula (I) is useful to prevent and treat hypertension and cardiac failure. ##STR1## in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, --S--R7, --SO2--R7, --C.tbd.C--R7 or --(CH2)p--OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, --A1.dbd.A2--A3.dbd.A4-- is --CH.dbd.CH--CH.dbd.CH--, --N.dbd.CH--CH.dbd.CH--, --CH.dbd.N--CH.dbd.CH--, --CH.dbd.CH--N.dbd.CH--, --CH.dbd.CH--CH.dbd.N-- or --CH.dbd.N--CH.dbd.N--, R2 and R3 are each hydrogen, a halogen, a lower alkyl, a lower alkoxy, a carbamoyl or cyano, R4 is hydrogen or a lower alkyl, R5 is 1H-tetrazol-5-yl, carboxyl (--COOH) or a carboxylic ester and R6 is hydrogen, a halogen, hydroxyl or a lower alkoxy, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: September 13, 1990
    Date of Patent: July 12, 1994
    Assignee: Eisai Co., Ltd.
    Inventors: Kazutoshi Miyake, Masayuki Matsukura, Naoki Yoneda, Osamu Hiroshima, Nobuyuki Mori, Hiroki Ishihara, Takashi Musha, Toshiyuki Matsuoka, Sachiyuki Hamano, Norio Minami
  • Biphenylmethane derivative and pharmacological use
    Patent number: 5298518
    Abstract: The biphenylmethane derivative having the formula (I) is useful to prevent and treat hypertension and cardiac failure. ##STR1## in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, --S--R7, --SO2--R7, --C.tbd.C--R7 or --(CH2)--OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, --A1.dbd.A2--A3.dbd.A4-- is CH.dbd.CH--CH.dbd.CH--, --N.dbd.CH--CH.dbd.CH--, --CH.dbd.N--CH.dbd.CH--, --CH.dbd.CH--N.dbd.CH--, --CH.dbd.CH--CH.dbd.N-- or --CH.dbd.N--CH.dbd.N--, R2 and R3 are each hydrogen, a halogen, a lower alkyl, a lower alkoxy, a carbamoyl or cyano, R4 is hydrogen or a lower alkyl, R5 is 1H-tetrazol-5-yl, carboxyl (--COOH) or a carboxylic ester and R6 is hydrogen, a halogen, hydroxyl or a lower alkoxy, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: March 6, 1992
    Date of Patent: March 29, 1994
    Assignee: Eisai Co., Ltd.
    Inventors: Kazutoshi Miyake, Masayuki Matsukura, Naoki Yoneda, Osamu Hiroshima, Nobuyuki Mori, Hiroki Ishihara, Takashi Musha, Toshiyuki Matsuoka, Sachiyuki Hamano, Norio Minami