Patents by Inventor Osamu Jodo

Osamu Jodo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4954438
    Abstract: This invention relates to a process for preparing an antibiotic D788-7 wherein, after culturing carborubicin-producing bacteria, the obtained culture liquid is extracted in acidic conditions while stirring to be absorbed to synthetic resin, followed by desorption from the resin and elution with acetone and the resulting acetone solution containing carborubicin is converted into an antibiotic D788-7 by photo radiation, for obtaining D788-7 in the purified form from the reaction solution. The production yield for D788-7 is extremely high and its use as an antitumor agent can be made possible.
    Type: Grant
    Filed: August 21, 1989
    Date of Patent: September 4, 1990
    Assignee: Sanraku Incorporated
    Inventors: Akihiro Yoshimoto, Osamu Jodo, Yoshio Watanabe, Rokuro Okamoto, Tomio Takeuchi
  • Patent number: 4918172
    Abstract: Disclosed are anthracycline antibiotics of a formula (I): ##STR1## in which R.sup.1 and R.sup.2 are hydroxyl groups, R.sup.3 is ethyl group, R.sup.4 is methoxycarbonyl group and X represents daunosamine-rhodenose or daunosamine-deoxyfucose; orR.sup.1 and R.sup.2 are hydroxyl groups, R.sup.3 is 1-hydroxyethyl group, R.sup.4 is hydrogen atom and X represents daunosamine-rhodenose or daunosamine-deoxyfucose; orR.sup.1, R.sup.2 and R.sup.4 are hydroxyl groups, R.sup.3 is ethyl group and X represents daunosamine-rhodenose, daunosamine-deoxyfucose, rhodosamine-rhodenose, N-monomethyldaunosamine-rhodenose or N-monomethyldaunosamine-deoxyfucose; orR.sup.1 is methoxy group, R.sup.2 is hydroxyl group, R.sup.3 is ethyl group, R.sup.4 is methoxycarbonyl group and X represents daunosamine-rhodenose or daunosamine-deoxyfucose; orR.sup.1 and R.sup.4 are hydroxy groups, R.sup.2 is hydrogen atom, R.sup.
    Type: Grant
    Filed: October 3, 1988
    Date of Patent: April 17, 1990
    Assignee: Sanraku Incorporated
    Inventors: Akihiro Yoshimoto, Osamu Jodo, Yoshio Watanabe, Rokuro Okamoto, Tomoyuki Ishikura, Hiroshi Naganawa, Tsutomu Sawa, Tomio Takeuchi
  • Patent number: 4897470
    Abstract: New anthracycline antibiotics of a formula (I) are provided, which are usable as an anticancer agent ##STR1## (where R represents a hydrogen atom or a hydroxyl group). The antibiotics (I) can be produced by incubation of a dye-nonproductive or hardly dye-productive mutant strain which has an ability of converting .alpha.-citromycinone or .beta.-isorhodomycinone into the antibiotics (I), in the presence of .alpha.-citromycinone or .beta.-isorhodomycinone in a pertinent nutrient medium.
    Type: Grant
    Filed: April 6, 1987
    Date of Patent: January 30, 1990
    Assignee: Sanraku Incorporated
    Inventors: Akihiro Yoshimoto, Osamu Jodo, Yoshio Watanabe, Tomoyuki Ishikura, Tsutomu Sawa, Tomio Takeuchi, Hamao Umezawa, deceased
  • Patent number: 4734493
    Abstract: The antibiotics designated obelmycins exhibit high proliferation inhibiting action against leukemia cells and are effective as anti-cancer agents.
    Type: Grant
    Filed: April 7, 1986
    Date of Patent: March 29, 1988
    Assignee: Sanraku, Incorporated
    Inventors: Akihiro Yoshimoto, Osamu Jodo, Yoshio Watanabe, Tomoyuki Ishikura, Tsutomu Sawa, Tomio Takeuchi, Hamao Umezawa