Abstract: A fertilized egg development stage determination method according to the invention includes: obtaining image data corresponding to an image of a fertilized egg captured by optical microscope; extracting a region corresponding to the fertilized egg in the image based on the image data and obtaining an index value indicating a degree of coincidence of the region with a circle; extracting a region corresponding to a zona pellucida of the fertilized egg in the image based on the image data and obtaining an index value indicating a thickness of the region; and determining a development stage of the fertilized egg based on the index value indicating the degree of coincidence, the index value indicating the thickness and determination criteria determined in advance for a combination of these index values.

Abstract: A D seat front beam has an inner end in a vehicle width direction fixed to a first column support point, and a point of fixation of the D seat front beam to the front lower pillar is provided further on a rear side in a vehicle front and rear direction than a first column support point. The D seat front beam extends toward an inner side in the vehicle width direction and toward the front side in the vehicle front and rear direction, from the point of fixation to the front lower pillar toward the first column support point.

Abstract: The instrument panel reinforcement includes a column attachment portion, a side end portion, and an inclined portion. The side end portion is fixed to a front lower pillar. The inclined portion is provided between the column attachment portion and the side end portion, extends toward an inner side in the vehicle width direction and toward a rear side in a vehicle front and rear direction from a bent portion at an inner end in the vehicle width direction of the side end portion, and is connected to the column attachment portion. A cowl to brace has a rear end fixed to the bent portion of the instrument panel reinforcement.

Abstract: A gusset is joined to an instrument panel reinforcement and a floor brace. The instrument panel reinforcement includes a D seat rear beam extending from a portion to be joined to the floor brace to a portion for supporting the steering column. The D seat rear beam includes a D seat upper beam having a hat-shaped cross section open toward a lower side. The gusset includes a reinforcement joint portion that is joined to the D seat upper beam to form a closed cross section.

Abstract: The instrument panel reinforcement includes a column attachment portion, a side end portion, and an inclined portion. The side end portion is fixed to a front lower pillar. The inclined portion is provided between the column attachment portion and the side end portion, extends toward an inner side in the vehicle width direction and toward a rear side in a vehicle front and rear direction from a bent portion at an inner end in the vehicle width direction of the side end portion, and is connected to the column attachment portion. A cowl to brace has a rear end fixed to the bent portion of the instrument panel reinforcement.

Abstract: A D seat front beam has an inner end in a vehicle width direction fixed to a first column support point, and a point of fixation of the D seat front beam to the front lower pillar is provided further on a rear side in a vehicle front and rear direction than a first column support point. The D seat front beam extends toward an inner side in the vehicle width direction and toward the front side in the vehicle front and rear direction, from the point of fixation to the front lower pillar toward the first column support point.

Abstract: A gusset is joined to an instrument panel reinforcement and a floor brace. The instrument panel reinforcement includes a D seat rear beam extending from a portion to be joined to the floor brace to a portion for supporting the steering column. The D seat rear beam includes a D seat upper beam having a hat-shaped cross section open toward a lower side. The gusset includes a reinforcement joint portion that is joined to the D seat upper beam to form a closed cross section.

Abstract: The present invention provides a separation container capable of preventing contamination with unnecessary components and efficiently separating a separation subject.

Abstract: A separation container that can prevent the contamination with unnecessary components is provided. A separation container 1 for separating a separation subject from a sample by causing the separation subject to gather on the bottom thereof by centrifugation includes a container main body 11 and a dividing portion. The container main body 11 is a tubular container elongated in the axial direction with an upper end thereof being open and a lower end thereof being the bottom. The dividing portion has a partition 12 formed along the axial direction of the container main body, and an inner space of the container main body 11 is divided into a sample supply chamber 14 and a separation subject discharge chamber 15 by the partition 12. The sample supply chamber 14 and the separation subject discharge chamber 15 communicate with each other via a through hole 13 formed in a lower portion of the partition 12.

Abstract: Heterocyclic compounds of the formula: wherein R1 is carboxy or protected carboxy, R2 is aryl which may have suitable substituent(s), R3 is aryl which may have suitable substituent(s), R4 is hydrogen, lower alkyl, hydroxy or aryl, A1 is lower alkylene, etc., etc. and n is 0 or 1, and pharmaceutically acceptable salts thereof which are useful as a medicament.

Abstract: Azole compounds of the formula: wherein R1 is lower alkyl substituted with carboxy, etc., R2 is hydrogen or lower alkyl, R3 is aryl, etc. R4 is aryl, etc. Q is  etc., and X is O, NH or S, and its salt, which are useful as medicament.

Abstract: Heterocyclic compounds of the formula: ##STR1## whereinR.sup.1 is carboxy or protected carboxy,R.sup.2 is aryl which may have suitable substituent(s),R.sup.3 is aryl which may have suitable substituent(s),A.sup.1 is lower alkylene,A.sup.2 is bond or lower alkylene and-Q- is ##STR2## etc., and pharmaceutically acceptable salts thereof which are useful as a medicament.

Abstract: This invention relates to new heterocyclic compounds, compositions, process of making and method of use thereof for inhibition of platelet aggregation, vasodilation, antihypertensive activity and prostaglandin I.sub.2 agonist.

Abstract: A compound or the formula: ##STR1## wherein R.sup.1 is carboxy or protected carboxy, R.sup.2 is hydrogen, hydroxy or protected hydroxy,R.sup.3 is hydrogen, hydroxy, protected hydroxy, etc.,R.sup.4 is hydrogen or halogen,A.sup.1 is lower alkylene,A.sup.2 is bond or lower alkylene,--R.sup.5 is ##STR2## (in which R.sup.6 is mono(or di or tri)aryl(lower)alkyl and Z is N or CH), etc., and ##STR3## etc., and a pharmaceutically acceptable salt thereof which are useful as medicaments.

Abstract: A compound of the formula ##STR1## wherein R.sup.1 is carboxy or protected carboxy,R.sup.2 is hydrogen, hydroxy or protected hydroxy,R.sup.3 is hydrogen, hydroxy, protected hydroxy, etc.,R.sup.4 is hydrogen or halogen,A.sup.1 is lower alkylene,A.sup.2 is bond or lower alkylene,--R.sup.5 is ##STR2## (in which R.sup.6 is mono(or di or tri)aryl(lower)alkyl and Z is N or CH), etc., and ##STR3## and a pharmaceutically acceptable salt thereof which are useful as medicaments.