Abstract: Binding members, especially antibody molecules that bind the IL-6:IL-6Ra complex formed by IL-6 and IL-6Ra, and do not bind either IL-6 or IL-6Ra alone. The binding members may have greater specificity for inhibiting pathological effects of IL-6 rather than beneficial effects of IL-6, as compared with binding members that bind IL-6 or IL-6Ra outside the IL-6:IL-6Ra complex.

Abstract: Binding members, especially antibody molecules that bind the IL-6:IL-6Ra complex formed by IL-6 and IL-6Ra, and do not bind either IL-6 or IL-6Ra alone. The binding members may have greater specificity for inhibiting pathological effects of IL-6 rather than beneficial effects of IL-6, as compared with binding members that bind IL-6 or IL-6Ra outside the IL-6:IL-6Ra complex.

Abstract: An active optical coupler between an optical bus line and subscribers. The optical coupler couples an emitting optical conductor and a receiving optical conductor and includes a diversion device that allows passage of a fraction of the incident light transmitted to the receiving conductor while diverting another fraction of this incident light energy to a photoreceiver which controls the injection of light energy into the optical coupler with a control in the form of a photoemitter for controlling the light energy transmitted to the receiving conductor with restoration of the level. A switch controls the operation of the photoemitter which in turn can be controlled either by the photoreceiver or by an input signal emitted by the subscriber. Digital data can be transmitted to subscribers by means of an optical bus line.

Abstract: An apparatus for automatically measuring the light transmission factor of liquid test samples in which a number of transparent vats is arranged around the circumference of a stationary table over which rotates a photoelectric measuring device which successively scans each vat to determine the light transmission factor of the samples. The various samples are automatically transferred by sucking them into the measuring vats from a bank of test tubes via a bank of probes with flexible hose connections to each vat; a central control valve drains the vats after testing. Electronic timing circuits provide the control commands for the operative sequences of the device, and logic circuitry, in combination with a data storage and retrieval system, provides comparative data between reference measurements and sample measurements for each vat.