Patents by Inventor Owen Callaghan
Owen Callaghan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10918515Abstract: A vaginal ring applicator having a polymeric barrel and at least one friction reducing agent, wherein the barrel is a flattened cylinder having two slightly curved and opposing sides connected by two arcs, wherein the barrel extends between an insertion end and a plunger end; and a plunger extending between distal and proximal ends, wherein the distal end of the plunger engages the plunger end of the barrel and wherein the plunger fits telescopically within the barrel.Type: GrantFiled: March 30, 2016Date of Patent: February 16, 2021Assignee: Merck Sharp & Dohme B.V.Inventors: Owen Callaghan, Cornelis P. M. Govers, Joris M. Swaak, Marco A. Voogsgerd, Mario A. A. de Zeeuw, Jesper Laursen, Klaas Sipkens
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Publication number: 20180243125Abstract: Described herein is a vaginal ring applicator comprising a barrel comprising a polymer and at least one friction reducing agent, wherein the barrel is a flattened cylinder having two slightly curved and opposing sides connected by two arcs, wherein the barrel extends between an insertion end and a plunger end; and a plunger extending between distal and proximal ends, wherein the distal end of the plunger engages the plunger end of the barrel and wherein the plunger fits telescopically within the barrel.Type: ApplicationFiled: March 30, 2016Publication date: August 30, 2018Inventors: Owen Callaghan, Cornelis P. M. Govers, Joris M. Swaak, Marco A. Voogsgerd, Mario A. A. de Zeeuw, Jesper Laursen, Klaas Sipkens
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Patent number: 8895745Abstract: The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.Type: GrantFiled: December 21, 2007Date of Patent: November 25, 2014Assignee: Astex Therapeutics LimitedInventors: Valerio Berdini, Gilbert Ebai Besong, Owen Callaghan, Maria Grazia Carr, Miles Stuart Congreve, Adrian Liam Gill, Charlotte Mary Griffiths-Jones, Andrew Madin, Christopher William Murray, Rajdeep Kaur Nijjar, Michael Alistair O'Brien, Andrew Pike, Gordon Saxty, Richard David Taylor, Emma Vickerstaffe
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Patent number: 8513276Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.Type: GrantFiled: December 21, 2007Date of Patent: August 20, 2013Assignee: Astex Therapeutics LimitedInventors: Valerio Berdini, Gilbert Ebai Besong, Owen Callaghan, Maria Grazia Carr, Miles Stuart Congreve, Adrian Liam Gill, Charlotte Mary Griffiths-Jones, Andrew Madin, Christopher William Murray, Rajdeep Kaur Nijjar, Michael Alistair O'Brien, Andrew Pike, Gordon Saxty, Richard David Taylor, Emma Vickerstaffe
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Patent number: 8131527Abstract: The present invention relates to FGFR pharmacophores, and in particular to compounds which are capable of binding to FGFR with greater affinity than their binding to VEGFR and methods of identifying such compounds using the pharmacophore. The present invention further relates to compositions, methods and uses of the compounds and the pharmacophores disclosed herein.Type: GrantFiled: December 21, 2007Date of Patent: March 6, 2012Assignee: Astex Therapeutics Ltd.Inventors: Gordon Saxty, Valerio Berdini, David Richard Newell, Owen Callaghan, Maria Grazia Carr, Miles Stuart Congreve, Adrian Liam Gill, Andrew Madin, Christopher William Murray
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Publication number: 20100120761Abstract: The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.Type: ApplicationFiled: December 21, 2007Publication date: May 13, 2010Applicant: Astex Therapeutics LimitedInventors: Valerio Berdini, Gilbert Ebai Besong, Owen Callaghan, Maria Grazia Carr, MIles Stuart Congreve, Adrian Liam Gill, Charlotte Mary Griffiths-Jones, Andrew Madin, Christopher William Murray, Rajdeep Kaur Nijjar, Michael Alistair O'Brien, Andrew Pike, Gordon Saxty, Richard David Taylor, Emma Vickerstaffe
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Publication number: 20100093718Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.Type: ApplicationFiled: December 21, 2007Publication date: April 15, 2010Inventors: Valerio Berdini, Gilbert Ebai Besong, Owen Callaghan, Maria Grazia Carr, Miles Stuart Congreve, Adrian Liam Gill, Charlotte Mary Griffiths-Jones, Andrew Madin, Christopher William Murray, Rajdeep Kaur Nijjar, Michael Alistair O'Brien, Andrew Pike, Gordon Saxty, Richard David Taylor, Emma Vickerstaffe
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Publication number: 20090221579Abstract: This invention relates to novel compounds having the structural formula Ia or formula Ib: Ia Ib and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of A? related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.Type: ApplicationFiled: October 14, 2005Publication date: September 3, 2009Inventors: Jeffrey Scott Albert, Don Andisik, James Arnold, Dean Brown, Owen Callaghan, James Campbell, Robin Arthur Ellis Carr, Gianni Chessari, Miles Stuart Congreve, Phil Edwards, James R. Empfield, Martyn Frederickson, Gerard M. Koether, Jennifer Krumrine, Russ Mauger, Christopher William Murray, Sahil Patel, Mark Sylvester, Scott Throner
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Publication number: 20090215777Abstract: The invention provides a compound for use as an inhibitor of Hsp90, the compound having the formula (I): or salts, tautomers, solvates or N-oxides thereof; wherein: A is N or a group CR3; R1 is a monocyclic or bicyclic carbocyclic or heterocyclic ring of 5 to 10 ring members of which up to two ring members may be heteroatoms selected from N, O and S and the remainder are carbon atoms, the carbocyclic or heterocyclic ring being optionally substituted by one or more substituent groups independently selected from R10; and R2, R3 and R10 are as defined in the claims.Type: ApplicationFiled: May 19, 2006Publication date: August 27, 2009Applicant: Astex Therapeutics Ltd.Inventors: Gianni Chessari, Miles Stuart Congreve, Owen Callaghan, Suzanna Ruth Cowan, Christopher William Murray, Alison Jo-Anne Woolford, Michael Alistair O'Brien, Andrew James Woodhead
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Publication number: 20090062282Abstract: This invention relates to novel compounds having the structural formula Ia or formula Ib below: (Ia, Ib), and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of A? related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.Type: ApplicationFiled: October 14, 2005Publication date: March 5, 2009Applicant: AstraZeneca ABInventors: Jeffrey Scott Albert, Don Andisik, James Arnold, Dean Brown, Owen Callaghan, James Campbell, Robin Arthur Ellis Carr, Gianni Chessari, Miles Stuart Congreve, Phil Edwards, James R. Empfield, Martyn Frederickson, Gerard M. Koether, Jennifer Krumrine, Russ Mauger, Christopher William Murray, Sahil Patel, Mark Sylvester, Scott Throner
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Publication number: 20080287399Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.Type: ApplicationFiled: December 12, 2005Publication date: November 20, 2008Applicant: AstraZeneca ABInventors: Jeffrey Scott Albert, Owen Callaghan, James Campbell, Robin Arthur Ellis Carr, Gianni Chessari, Suzanna Cowan, Miles Stuart Congreve, Phil Edwards, Martyn Frederickson, Christopher William Murray, Sahil Patel
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Patent number: D726313Type: GrantFiled: November 8, 2013Date of Patent: April 7, 2015Assignee: Merck Sharp & Dohme B.V.Inventors: Cornelius P. M. Govers, Owen Callaghan, Mario A. A. de Zeeuw, Joris M. Swaak, Marco A. Voogsgerd