Patents by Inventor Pablo G. Debenedetti

Pablo G. Debenedetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of protein microparticles by supercritical fluid precipitation
    Patent number: 6063910
    Abstract: The present invention comprises passing a solution of a soluble material, preferably a protein, in a solvent through a continuum of supercritical antisolvent fluid and precipitating the soluble material. This can be conducted by passing the solution through the continuum of supercrital fluid in the form of droplets, which can be sprayed through the supercritical fluid. The plurality of droplets can be passed cocurrently or countercurrently with respect to a stream of antisolvent fluid. Alternatively, the solution can be passed through the continuum of supercritical antisolvent fluid in the form of a thin film or a plurality of fine streams.
    Type: Grant
    Filed: November 14, 1991
    Date of Patent: May 16, 2000
    Assignee: The Trustees of Princeton University
    Inventors: Pablo G. Debenedetti, Gio-Bin Lim, Robert K. Prud'Homme