Patents by Inventor Padma Marwah
Padma Marwah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110028711Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: ApplicationFiled: October 15, 2010Publication date: February 3, 2011Inventors: Henry A. Lardy, Ashok Marwah, Padma Marwah
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Patent number: 7842680Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: GrantFiled: March 17, 2009Date of Patent: November 30, 2010Assignee: Harbor BioSciences, Inc.Inventors: Henry A. Lardy, Padma Marwah, Ashok Marwah
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Publication number: 20100240633Abstract: The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods and compositions suitable for therapeutic applications.Type: ApplicationFiled: June 3, 2010Publication date: September 23, 2010Applicant: Harbor BioSciences, Inc.Inventors: Henry A. Lardy, Padma Marwah, James M. Frincke
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Patent number: 7638509Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: GrantFiled: March 17, 2009Date of Patent: December 29, 2009Assignee: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry A. Lardy, Padma Marwah, Ashok Marwah
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Publication number: 20090181936Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: ApplicationFiled: March 17, 2009Publication date: July 16, 2009Applicant: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry A. Lardy, Ashok Marwah, Padma Marwah
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Publication number: 20090176752Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: ApplicationFiled: March 17, 2009Publication date: July 9, 2009Applicant: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry A. Lardy, Ashok Marwah, Padma Marwah
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Patent number: 7550450Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: GrantFiled: September 26, 2007Date of Patent: June 23, 2009Assignee: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry A. Lardy, Ashok Marwah, Padma Marwah
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Patent number: 7514420Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: GrantFiled: August 13, 2007Date of Patent: April 7, 2009Assignee: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry A. Lardy, Padma Marwah, Ashok Marwah
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Patent number: 7462610Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: GrantFiled: August 11, 2007Date of Patent: December 9, 2008Assignee: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry A. Lardy, Padma Marwah, Ashok Marwah
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Publication number: 20080176823Abstract: The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods and compositions suitable for therapeutic applications.Type: ApplicationFiled: August 7, 2007Publication date: July 24, 2008Applicant: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry A. Lardy, Padma Marwah, James M. Frincke
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Publication number: 20080070881Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: ApplicationFiled: September 26, 2007Publication date: March 20, 2008Applicant: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry Lardy, Ashok Marwah, Padma Marwah
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Publication number: 20080058301Abstract: The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods and compositions suitable for therapeutic applications.Type: ApplicationFiled: August 7, 2007Publication date: March 6, 2008Applicant: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry Lardy, Padma Marwah, James Frincke
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Publication number: 20080021006Abstract: The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods and compositions suitable for therapeutic applications.Type: ApplicationFiled: August 7, 2007Publication date: January 24, 2008Applicant: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry Lardy, Padma Marwah, James Frincke
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Publication number: 20080009472Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: ApplicationFiled: August 11, 2007Publication date: January 10, 2008Applicant: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry Lardy, Ashok Marwah, Padma Marwah
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Publication number: 20080004250Abstract: The instant invention provides potent antiandrogen compounds, such as 3?-acetoxyandrost-1,5-diene-17-ethylene ketal and 3?-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: ApplicationFiled: August 13, 2007Publication date: January 3, 2008Applicant: Hollis-Eden Pharmaceuticals, Inc.Inventors: Henry Lardy, Ashok Marwah, Padma Marwah
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Publication number: 20060079492Abstract: The invention relates to the use of compounds to treat a number of conditions, such as thrombocytopenia, neutropenia or the delayed effects of radiation therapy. Compounds that can be used in the invention include methyl-2,3,4-trihydroxy-1-O-(7,17-dioxoandrost-5-ene-3?-yl)-?-D-glucopyranosiduronate, 16?,3?-dihydroxy-5?-androstan-17-one or 3,7,16,17-tetrahydroxyandrost-5-ene, 3,7,16,17-tetrahydroxyandrost-4-ene, 3,7,16,17-tetrahydroxyandrost-1-ene or 3,7,16,17-tetrahydroxyandrostane that can be used in the treatment method.Type: ApplicationFiled: September 23, 2005Publication date: April 13, 2006Inventors: Clarence Ahlem, Christopher Reading, James Frincke, Dwight Stickney, Henry Lardy, Padma Marwah, Ashok Marwah, Patrick Prendergast
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Publication number: 20040242618Abstract: The instant invention provides potent antiandrogen compounds, such as 3&bgr;-acetoxyandrost-1,5-diene-17-ethylene ketal and 3&bgr;-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.Type: ApplicationFiled: March 30, 2004Publication date: December 2, 2004Inventors: Henry A. Lardy, Ashok Marwah, Padma Marwah
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Patent number: 6686486Abstract: A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of a periodic acid or metal periodate and an alkyl hydroperoxide under conditions of normal as well as elevated pressure of a suitable gas like air. The reaction can conveniently be conducted at temperatures between about 0-65° C. in a cosolvent system of water and organic solvent(s).Type: GrantFiled: August 14, 2000Date of Patent: February 3, 2004Inventors: Padma Marwah, Henry A. Lardy
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Patent number: 6607000Abstract: A frilly dental floss formed of thin wide ribbon with frilly edge(s) or centrally located slits or the combination thereof, made from a strong, naturally waxy, polymer material preferably from a biodegradable, thin-gauged high-density polyethylene (HDPE) material.Type: GrantFiled: December 27, 2000Date of Patent: August 19, 2003Inventors: Padma Marwah, Ashok Kumar Marwah
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Publication number: 20030083231Abstract: The invention relates to the use of compounds to treat a number of conditions, such as thrombocytopenia, neutropenia or the delayed effects of radiation therapy. Compounds that can be used in the invention include methyl-2,3,4-trihydroxy-1-O-(7,17-dioxoandrost-5-ene-3&bgr;-yl)-&bgr;-D-glucopyranosiduronate, 16&agr;,3&agr;-dihydroxy-5&agr;-androstan-17-one or 3,7,16,17-tetrahydroxyandrost-5-ene, 3,7,16,17-tetrahydroxyandrost-4-ene,3,7,16,17-tetrahydroxyandrost-1-ene or 3,7,16,17-tetrahydroxyandrostane that can be used in the treatment method.Type: ApplicationFiled: March 1, 2002Publication date: May 1, 2003Inventors: Clarence N. Ahlem, Christopher Reading, James Frincke, Dwight Stickney, Henry A. Lardy, Padma Marwah, Ashok Marwah, Patrick T. Prendergast