Patents by Inventor Paige Mahaney
Paige Mahaney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20070203207Abstract: 2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 3-position being a substituted phenyl group and at the 2-position being a methyl cycloalkyl ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.Type: ApplicationFiled: April 23, 2007Publication date: August 30, 2007Inventors: Fred Bizzarro, Wendy Corbett, Joseph Grippo, Nancy-Ellen Haynes, George Holland, Robert Kester, Paige Mahaney, Ramakanth Sarabu
-
Publication number: 20070135449Abstract: A process for the enantioselective synthesis of an (S)— or (R)-1-[2-dimethylamino)-1-(methoxyphenyl)ethyl]cyclohexanol and analogues or salt thereof are described.Type: ApplicationFiled: December 4, 2006Publication date: June 14, 2007Applicant: WyethInventors: Paige Mahaney, Madelene Antane, Jerry Sun
-
Publication number: 20070072897Abstract: The present invention is directed to phenylaminopropanol derivatives of formulae I, II, and III: or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, schizophrenia, and combinations thereof.Type: ApplicationFiled: September 27, 2006Publication date: March 29, 2007Applicant: WyethInventors: Paige Mahaney, Gavin Heffernan, Richard Coghlan, Stephen Cohn, Callain Kim, Douglas Jenkins, Michael Marella, Casey McComas, Joseph Sabatucci, Eugene Terefenko, Eugene Trybulski, An Vu, Fei Ye, Puwen Zhang
-
Publication number: 20060178429Abstract: 2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.Type: ApplicationFiled: April 10, 2006Publication date: August 10, 2006Inventors: Wendy Corbett, Joseph Grimsby, Nancy-Ellen Haynes, Robert Kester, Paige Mahaney, Jagdish Racha, Ramakanth Sarabu, Ka Wang
-
Publication number: 20060160815Abstract: This invention provides estrogen receptor modulators having the structure: wherein R1 to R7, R9 and R10 X, Y, and Z are as defined in the specification; or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: December 16, 2005Publication date: July 20, 2006Applicant: WyethInventors: Joseph Sabatucci, Fei Ye, Paige Mahaney
-
Publication number: 20060019961Abstract: The present invention relates to estrogen receptor ligands, and compounds and methods for treating diseases associated with excessive estrogen receptor activity.Type: ApplicationFiled: June 8, 2005Publication date: January 26, 2006Inventors: Paige Mahaney, Michael Webb, Fei Ye, Joseph Sabatucci
-
Publication number: 20050261503Abstract: 2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 3-position being a substituted phenyl group and at the 2-position being a methyl cycloalkyl ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.Type: ApplicationFiled: April 4, 2005Publication date: November 24, 2005Inventors: Fred Bizzaro, Wendy Corbett, Joseph Grippo, Nancy-Ellen Haynes, George Holland, Robert Kester, Paige Mahaney, Ramakanth Sarabu
-
Publication number: 20050234058Abstract: The present invention is directed to secondary amino- and cycloamino-cycloalkanol derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: October 12, 2004Publication date: October 20, 2005Applicant: WyethInventors: Paige Mahaney, Michael Webb, Lori Gavrin, Eugene Trybulski
-
Publication number: 20050222148Abstract: The present invention is directed to phenylaminopropanol derivatives of formula I: or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: March 28, 2005Publication date: October 6, 2005Applicant: WyethInventors: Callain Kim, Paige Mahaney, Eugene Trybulski, Puwen Zhang, Eugene Terefenko, Casey McComas, Michael Marella, Richard Coghlan, Gavin Heffernan, Stephen Cohn, An Vu, Joseph Sabatucci, Fei Ye
-
Publication number: 20050222142Abstract: The present invention is directed to phenylaminopropanol derivatives of formula I: or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: March 28, 2005Publication date: October 6, 2005Applicant: WyethInventors: An Vu, Paige Mahaney, Stephen Cohn
-
Publication number: 20050192283Abstract: The present invention is directed to fused-aryl and heteroaryl derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: October 12, 2004Publication date: September 1, 2005Applicant: WyethInventors: Eugene Trybulski, Paige Mahaney, Lori Gavrin, Joseph Sabatucci, Gary Stack
-
Publication number: 20050187251Abstract: The present invention is directed to substituted N-heterocycle derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: October 12, 2004Publication date: August 25, 2005Applicant: WyethInventors: Paige Mahaney, Lori Gavrin, Douglas Jenkins
-
Publication number: 20050171115Abstract: The present invention is directed to alkanoyl and cycloalkanoyl-amine derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: October 12, 2004Publication date: August 4, 2005Applicant: WyethInventors: Eugene Trybulski, Paige Mahaney, Lori Gavrin, William Moore, Joseph Sabatucci
-
Publication number: 20050148595Abstract: The present invention is directed to arylalkyl- and cycloalkylalkyl-piperazine derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: October 12, 2004Publication date: July 7, 2005Applicant: WyethInventor: Paige Mahaney
-
Publication number: 20050143394Abstract: The present invention is directed to phenylpiperazine cycloalkanol derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: October 12, 2004Publication date: June 30, 2005Applicant: WyethInventors: Paige Mahaney, Eugene Trybulski, Lori Gavrin, An Vu
-
Publication number: 20050143579Abstract: The present invention is directed to substituted aryl cycloalkanoyl derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.Type: ApplicationFiled: October 12, 2004Publication date: June 30, 2005Applicant: WyethInventors: Eugene Trybulski, Joseph Sabatucci, An Vu, Stephen Cohn, Arthur Santilli, Lori Gavrin, Fei Ye, Paige Mahaney