Abstract: The present disclosure relates to a process for preparing antibodies with a defined glycosylation pattern, in particular antibodies with a glycan terminating in an N-acetylglucosamine. The antibodies of the disclosure are suitable for use in a process to conjugate a payload thereto. The disclosure also extends to molecules obtained and obtainable from the process disclosed herein, novel molecules and intermediates, compositions comprising said molecules and uses of the molecules and compositions, particularly in treatment, for example in the treatment of cancer.

Abstract: The present disclosure relates to a process for preparing antibodies with a defined glycosylation pattern, in particular antibodies with a glycan terminating in an N-acetylglucosamine. The antibodies of the disclosure are suitable for use in a process to conjugate a payload thereto. The disclosure also extends to molecules obtained and obtainable from the process disclosed herein, novel molecules and intermediates, compositions comprising said molecules and uses of the molecules and compositions, particularly in treatment, for example in the treatment of cancer.

Abstract: A decal removal assembly includes a plate that is structured to have a steam space extending therein. The plate may be positioned proximate a surface such that the steam space surrounds a decal adhered to the surface. A handle is attached to the plate and the handle is in fluid communication with the steam space. A nozzle is attached to the handle and the nozzle has a distal end with respect to the handle. The nozzle is in fluid communication with the steam space and the distal end may be fluidly coupled to a steam source. Steam from the steam source is directed into the steam space thereby facilitating removal of the decal from the surface. A plurality of couplers is provided and each of the couplers is attached to the plate. Each of the couplers engages the surface such that the plate is retained on the surface and each of the couplers is positioned proximate one of four corners of the plate.

Abstract: A non-irritating antimicrobial multi-layer or multi-ply tissue product made by treating an inner layer or ply or an inner surface of an inner layer or ply with one or more antimicrobial agents and treating the one or more outer layers or plies or the outer surfaces of the layers or plies with one or more irritation-inhibiting agents, and methods of making and using the same. The antimicrobial agent will remain confined to the inner portion of the tissue product, thereby preventing irritation to the user, and the irritation-inhibiting composition treated layer(s) or ply(s) provides a pleasing, soothing, non-irritating tactile quality to the tissue product. The non-irritating antimicrobial multi-layer or multi-ply tissue product further comprises an absorption enhancing agent. In one embodiment, the irritation-inhibiting composition comprises an oil, in which case the tissue product will also entrap any absorbed contaminant, holding it in contact with the antimicrobial agent.

Abstract: A sheet-like product is disclosed having a patterned indicia for signifying the existence of an additive or ingredient that is contained within the product. The present inventors have discovered that a particular burst-like pattern provides various advantages and benefits in comparison to other patterns. In order to differentiate patterns of the present invention from other patterns, patterns made according to present invention were image analyzed during a dilation process.

Abstract: A non-irritating antimicrobial multi-layer or multi-ply tissue product made by treating an inner layer or ply or an inner surface of an inner layer or ply with one or more antimicrobial agents and treating the one or more outer layers or plies or the outer surfaces of the layers or plies with one or more irritation-inhibiting agents, and methods of making and using the same. The antimicrobial agent will remain confined to the inner portion of the tissue product, thereby preventing irritation to the user, and the irritation-inhibiting composition treated layer(s) or ply(s) provides a pleasing, soothing, non-irritating tactile quality to the tissue product. The non-irritating antimicrobial multi-layer or multi-ply tissue product further comprises an absorption enhancing agent. In one embodiment, the irritation-inhibiting composition comprises an oil, in which case the tissue product will also entrap any absorbed contaminant, holding it in contact with the antimicrobial agent.

Abstract: The present invention is a poufable product that is capable of being converted into a pouf product. The poufable product is comprised of at least one flat ply of flexible sheet material having at least one side edge and at least one cord. The cord engages at least one ply of the flexible sheet material such that the flexible sheet material is capable of bunching on or about the cord.

Abstract: A method for navigating within a software application of an electronic device, such as a computer, personal digital assistant or global positioning system, using a scrolling navigational ribbon. In one embodiment, information is obtained by scrolling the ribbon to the left or right by clicking on left or right arrows until the user-selectable descriptive title of the required information appears. In another embodiment, the ribbon is scrolled by clicking on a grab bar beneath the ribbon and moving it to the right or left. The user then clicks on the required title, and the information appears on the screen. The descriptive title is placed in a field above the ribbon, known as the breadcrumb field. When the required information is more than one layer down in the hierarchy of the information database, descriptive titles on the scrolling ribbon change with each selection to reflect the next layer of information.

Abstract: The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating human ovarian cancers. A variety of novel markers are provided, wherein changes in the levels of expression of one or more of the markers is correlated with the presence of ovarian cancer.