Abstract: A system, apparatus and method evaluates samples or analytes using a point-of-care device. A test selection is received from the user interface. A determination is made whether a test cartridge connected to the test cartridge interface matches the test selection. Properties of the sample or the analyte are detected using detector(s) or sensor(s) in the POC device. A test results data based on the properties is generated. A report based on an analysis of the test results data is generated and the report is provided to the user interface of the POC device. The POC device also includes memory, communication interface(s), test cartridge interface, and processor(s).