Abstract: A two component interpenetrating polymer network wound dressing material is formed of a biocompatible, hydrophilic first component such as gelatin or polyvinyl alcohol and a biocompatible elastomer such as HydroThane (trademark) by dissolving the components in a common solvent, initiating cross-linking of at least one of the components in the solution, and forming a film, fiber, bead or mesh from the solution.

Abstract: A medicated multi-layered polyurethane foam dressing and drug delivery device with cooling properties, used in body cavities and on damaged tissues, particularly bums. The dressing may have at least one therapeutic agent dispersed into the polyurethane layers; an optional outer layer of either a hydrogel formulated from a polyurethane or an adhesive elastomeric material; an optional drug-free fluid-retaining layer and/or a drug-reservoir layer, each comprised of hydrophilic polyurethane foam; a non-adherent, drug-loaded surface-contacting layer of a polyurethane hydrogel; and an optional cover sheet, for surface dressings. An interposed liquid transfer control may be used at a layer interface. The conformable dressing shapes include cylindrical, oval, flatsheets in pre-determined sizes; and may be secured with a secondary dressing. The contact surface may be channeled to enhance fluid distribution.